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Heavy marijuana use increases schizophrenia in men, study finds

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Re: Heavy marijuana use increases schizophrenia in men, study finds

#131

Post by progmetaldev »

yieldcrv wrote: post #26
rdruxn wrote: post #17

Earlier quoted context omitted.

I would counter that by pointing out that if your aim is to achieve a certain degree of bioavailability of TCH, you'd have to smoke a larger quantity of a lower-potency product, thus exposing yourself to more of the combustion by-products than necessary.

I’m primarily an edibles consumer I wish marijuana use wasn’t assumed to be “smoking” by default most questionnaires and even dating apps are like do you smoke marijuana

I agree with you, but I think the bigger thing is that people do not understand that edibles affect people far differently than smoking does. Not just the effects, but the way the body metabolizes the substance. That information should really be more available, especially as cannabis legalization increases. Too many heavy smokers end up taking edibles and having a horrible time because they thought they needed a high amount of edibles to match their smoking habits.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#132

Post by muffles »

whats_a_quasar wrote: post #41

There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…

> Once someone has a psychotic episode, they are much likelier to have more.

An anecdotal observation of this in media is when comedian Owen Benjamin took a "Stars of Death" edible on the Joey Diaz podcast. It was argued that this was the point his big break with reality occurred (delusions and conspiracy seen everywhere). Another interesting observation is that THC seems to intensify the effect of amphetamines like Adderall. With the increase in ADHD and the presumable fix of amphetamine style drugs like Adderall common marijuana usage could intensify the amphetamine high massively which can exacerbate delusions and psychosis even further. Owen himself was known to use Adderall before shows to maintain focus. Quite an interesting area of research.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#133

Post by operatingthetan »

muffles wrote: post #132
whats_a_quasar wrote: post #41

There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…

> Once someone has a psychotic episode, they are much likelier to have more. An anecdotal observation of this in media is when comedian Owen Benjamin took a "Stars of Death" edible on the Joey Diaz podcast. It was argued that this was the point his big break with reality occurred (delusions and conspiracy seen everywhere). Another interesting observation is that THC seems to intensify the effect of amphetamines like…

Plus that combo gives guaranteed insomnia. The user wakes up from whatever sleep they did get, takes the speed again, and it's like nothing happened. This continued loss of sleep compounds over time and can contribute to psychosis.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#134

Post by iamnotsure »

hirvi74 wrote: post #114
iamnotsure wrote: post #61

Frequent mouse button clicks increase software hangs in desktop environments, study finds. (MJ is an ancient medicine, it can't and won't cause any disease; proper use is a remedy for many)

> it can't and won't cause any disease; I suppose Cannabinoid Hyperemesis Syndrome does not count? I love the plant probably more than most, but like most things -- it has it's good parts and it's parts.

I guess for anything exists an individual frequency that when exceeded causes some kind of discomfort, which could then be named x hyper_y syndrome.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#135

Post by EdwardDiego »

muffles wrote: post #132
whats_a_quasar wrote: post #41

There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…

> Once someone has a psychotic episode, they are much likelier to have more. An anecdotal observation of this in media is when comedian Owen Benjamin took a "Stars of Death" edible on the Joey Diaz podcast. It was argued that this was the point his big break with reality occurred (delusions and conspiracy seen everywhere). Another interesting observation is that THC seems to intensify the effect of amphetamines like…

I have ADHD treated with methylphenidate, and smoke weed recreationally, and that "interesting observation" doesn't align with my experiences at all.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#136

Post by callalex »

burnished wrote: post #90
bitcoin_anon wrote: post #83

Earlier quoted context omitted.

Kind of like how Everclear dominates the alcohol industry?

That analogy doesn't quite fit because as alcohol increases in purity it reaches a point where it starts to damage tissues it comes into contact with. A better example would be 4loko when it introduced caffeine, which is contrary to the point you were trying to make.

The equivalent to your example would be gummies with added caffeine content to counteract the sleepy effects, which was the same reason 4loko did it. The Everclear example still stands.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#137

Post by pnathan »

This confirms the widespread anecdotes online, where so and so's friend smoked way too much and had a mental break(more rarely, the sufferer speaks for themselves).

I'm glad to see research on this, but I hope it doesn't spawn another wave of reflexive & unthinking anti-drug legislation.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#138

Post by xupybd »

sjc02060 wrote: post #92
xupybd wrote: post #88

My father was a mental health social worker. He worked with youths, mainly teens. In his experience the vast majority of teens that ended up in his hospital had some drug fueled episode that led to their mental health crisis. He told me that he didn't think the drugs caused the mental illness but we're often the trigger. That is these kids already had a mental illness that had not started to present symptoms until it…

Is that to assume these kids would've got mentally ill anyway, just later down the line?

I suspect so. My Father was only observing what he saw. He wasn't researching the cause.

The key take away for me was that he was working with young people. I suspect these people may have ended up in mental health care but much later in life.

If this were true you'd expect less of the later in life diagnoses to be drug related. I have no data on that.

Re: Heavy marijuana use increases schizophrenia in men, study finds

#139

Post by balfirevic »

peterfirefly wrote: post #11
16bitvoid wrote: post #10

Earlier quoted context omitted.

I can't speak to its validity, but the way it was explained to me from a neuroscientist a few years ago is that the general hypothesis now is that some people have a genetic predisposition to schizophrenia and that predisposition sort of lies dormant until triggered. That would explain how both could be true: it could be genetic and triggered by environment/trauma.

There are enough cases of identical twins where one twin gets it and the other doesn't that we are certain it can't just be genetic. We are also certain that genes matter. We even know roughly which genes and that many of the variants that increase the risk are de novo mutations. We don't know much more than that, though.

> There are enough cases of identical twins where one twin gets it and the other doesn't that we are certain it can't just be genetic.

Strictly logically speaking, this is consistent with it being genetic + random chance (where the odds are determined only by your genes) - meaning no identifiable environmental factors. Not saying it is (nor would I know).

Re: Heavy marijuana use increases schizophrenia in men, study finds

#140

Post by [deleted] »

whats_a_quasar wrote: post #41

There's a really interesting line of research that suggests Schizophrenia is a spectrum, rather than a binary. Lots of people have personality traits that are similar to schizophrenics or have genetic risk factors for the condition. Some of those people develop the full disorder, and some don't. There's evidence that the reason for the split is that psychosis is itself damaging. Once someone has a psychotic episode,…

[deleted]
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