People are upvoting this because it has the “Alpha______” prefix. Meanwhile, everyone in the field of genomics knows that AlphaGenome provides essentially zero improvements over the previous SOTA, Borzoi…
AlphaGenome Atlas: a high-resolution map of human DNA
121–130 of 132 posts
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#122Earlier quoted context omitted.
Now I'm curious. What is the better mapping and streetview tool at this point?
For maps there's quite a few, just anything that doesn't have the amount of ads beats it. For Streetview apple lookaround is a better experience if it's mapped well in your area. I believe Google has been trying to improve their Streetview in coverage as apple has become a concurrent, but it still has the same bugs people have been complaining about for years (like going backward when pressing forward type of bad). I…
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#123Re: AlphaGenome Atlas: a high-resolution map of human DNA
#124Earlier quoted context omitted.
23andMe and similar companies don't transcribe your entire genome because that would cost way more than they charge you. They just sample a few tiny sections of it.
fwiw sequencing your entire genome only costs $400 or so from providers like sequencing.com
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#125not my field so I can't judge how useful it is but assuming this data can be used for drug discovery and their ToS limiting to non-commercial use only. Does DeepMind plan on selling this data to pharmaceutical companies?
Probably. I know Google has partnerships with Pharma: https://www.merck.com/news/merck-and-google-cloud-partner-to...
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#126In another HN thread about this AlphaGenome Atlas, someone has posted a link to: https://www.science.org/content/blog-post/mutate-em-all-and-... which comments the results of this study: https://www.biorxiv.org/content/10.64898/2026.07.25.740675v1 That study has done in reality what the AlphaGenome Atlas does in fiction, but instead for a human they have done it for one of the simplest viruses. So they have fuzzed th…
Yep. Sequence-to-function models are still very limited. AlphaGenome Atlas, despite the flashy branding, is unlikely to provide significant benefit to researchers.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#127Earlier quoted context omitted.
fwiw sequencing your entire genome only costs $400 or so from providers like sequencing.com
Thank you for the recommendation! I've been on a lookout for an affordable full sequence and 400$ is very reasonable. Very excited to just have my DNA on my own computer - this feels like the good kind of sci-fi :)
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#128In another HN thread about this AlphaGenome Atlas, someone has posted a link to: https://www.science.org/content/blog-post/mutate-em-all-and-... which comments the results of this study: https://www.biorxiv.org/content/10.64898/2026.07.25.740675v1 That study has done in reality what the AlphaGenome Atlas does in fiction, but instead for a human they have done it for one of the simplest viruses. So they have fuzzed th…
I would not group AlphaGenome into the pile of failed predictions of other models. AlphaGenome deserves to get evaluated based off its own merits.
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#129Don't be put off by the box asking for your "affiliation". I wrote "None", clicked submit and it took me straight to the Atlas.
As someone who regularly investigates whole genomes I would love to use this as a tool on novel mutations. These folks are the edge cases no one else could figure out that I get a crack at. Beyond the DNA we have the symptoms and lab work and I can usually narrow it down to a handful of guesses, but it sure would be nice to use this to help rank where to invest efforts.
For now i'll treat it as just another fun Google project that might come out of beta one day (or not).
Re: AlphaGenome Atlas: a high-resolution map of human DNA
#130Earlier quoted context omitted.
Thank you for the recommendation! I've been on a lookout for an affordable full sequence and 400$ is very reasonable. Very excited to just have my DNA on my own computer - this feels like the good kind of sci-fi :)
What are their data privacy and security policies? That is an important consideration.
There is a "permanent delete my data" option, but there's no independent audit that permanent delete actually deletes anything. If you're in EU/California they kinda have to take delete seriously due to GDPR and CCPA, so I think you're safer here.
I've been thinking about this a lot, and I'm not sure how "protectable" your DNA actually is because of how easy it is to get if somebody wants to. Obviously having your DNA in US government is bad, but they likely have it already.
As I'm an EU citizen I will get the data and use the delete option with fingers crossed that US government doesn't want to destroy me for whatever reason. Seems like they have their hands full with other kinds of destruction anyway lol