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AlphaGenome Atlas: a high-resolution map of human DNA

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Re: AlphaGenome Atlas: a high-resolution map of human DNA

#121

People are upvoting this because it has the “Alpha______” prefix. Meanwhile, everyone in the field of genomics knows that AlphaGenome provides essentially zero improvements over the previous SOTA, Borzoi…

They did benchmark the model and beat the SOTA on every metric though

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#122

Earlier quoted context omitted.

Now I'm curious. What is the better mapping and streetview tool at this point?

For maps there's quite a few, just anything that doesn't have the amount of ads beats it. For Streetview apple lookaround is a better experience if it's mapped well in your area. I believe Google has been trying to improve their Streetview in coverage as apple has become a concurrent, but it still has the same bugs people have been complaining about for years (like going backward when pressing forward type of bad). I…

As someone that just started working on Google Street View, do you links to any of those bugs? Curious to take a look and see what those problems are

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#123
post #20

Earlier quoted context omitted.

i made no such comment. reported for harassment.

You deleted the verbatim comment after it was pointed out. One was in thread and one was a stand alone comment. I was curious which was the throwaway so clicked into both profiles

[dead]

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#124
post #100

Earlier quoted context omitted.

23andMe and similar companies don't transcribe your entire genome because that would cost way more than they charge you. They just sample a few tiny sections of it.

fwiw sequencing your entire genome only costs $400 or so from providers like sequencing.com

Thank you for the recommendation! I've been on a lookout for an affordable full sequence and 400$ is very reasonable. Very excited to just have my DNA on my own computer - this feels like the good kind of sci-fi :)

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#125
post #8

not my field so I can't judge how useful it is but assuming this data can be used for drug discovery and their ToS limiting to non-commercial use only. Does DeepMind plan on selling this data to pharmaceutical companies?

Probably. I know Google has partnerships with Pharma: https://www.merck.com/news/merck-and-google-cloud-partner-to...

This is just typical enterprise "use AI" infrastructure, not hyper specialized drug research.

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#126

In another HN thread about this AlphaGenome Atlas, someone has posted a link to: https://www.science.org/content/blog-post/mutate-em-all-and-... which comments the results of this study: https://www.biorxiv.org/content/10.64898/2026.07.25.740675v1 That study has done in reality what the AlphaGenome Atlas does in fiction, but instead for a human they have done it for one of the simplest viruses. So they have fuzzed th…

Yep. Sequence-to-function models are still very limited. AlphaGenome Atlas, despite the flashy branding, is unlikely to provide significant benefit to researchers.

May be that's the reason for the alpha naming. We are waiting for a stable release (just kidding).

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#127
post #100

Earlier quoted context omitted.

fwiw sequencing your entire genome only costs $400 or so from providers like sequencing.com

Thank you for the recommendation! I've been on a lookout for an affordable full sequence and 400$ is very reasonable. Very excited to just have my DNA on my own computer - this feels like the good kind of sci-fi :)

What are their data privacy and security policies? That is an important consideration.

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#128

In another HN thread about this AlphaGenome Atlas, someone has posted a link to: https://www.science.org/content/blog-post/mutate-em-all-and-... which comments the results of this study: https://www.biorxiv.org/content/10.64898/2026.07.25.740675v1 That study has done in reality what the AlphaGenome Atlas does in fiction, but instead for a human they have done it for one of the simplest viruses. So they have fuzzed th…

> And various dedicated AI models all made poor predictions of the results of that experiment, which casts doubts about the value of the AlphaGenome predictive map

I would not group AlphaGenome into the pile of failed predictions of other models. AlphaGenome deserves to get evaluated based off its own merits.

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#129
post #106

Don't be put off by the box asking for your "affiliation". I wrote "None", clicked submit and it took me straight to the Atlas.

The agreement does pretty much state you can't use this for anything useful.

As someone who regularly investigates whole genomes I would love to use this as a tool on novel mutations. These folks are the edge cases no one else could figure out that I get a crack at. Beyond the DNA we have the symptoms and lab work and I can usually narrow it down to a handful of guesses, but it sure would be nice to use this to help rank where to invest efforts.

For now i'll treat it as just another fun Google project that might come out of beta one day (or not).

Re: AlphaGenome Atlas: a high-resolution map of human DNA

#130
post #127

Earlier quoted context omitted.

Thank you for the recommendation! I've been on a lookout for an affordable full sequence and 400$ is very reasonable. Very excited to just have my DNA on my own computer - this feels like the good kind of sci-fi :)

What are their data privacy and security policies? That is an important consideration.

I did fair amount of research, and it seems like they take it seriously with GDPR, HIPAA etc. and all the privacy legalities, but obviously Uncle Sam will have his way with it as it's a US based company (California). They will share your DNA if legally compelled.

There is a "permanent delete my data" option, but there's no independent audit that permanent delete actually deletes anything. If you're in EU/California they kinda have to take delete seriously due to GDPR and CCPA, so I think you're safer here.

I've been thinking about this a lot, and I'm not sure how "protectable" your DNA actually is because of how easy it is to get if somebody wants to. Obviously having your DNA in US government is bad, but they likely have it already.

As I'm an EU citizen I will get the data and use the delete option with fingers crossed that US government doesn't want to destroy me for whatever reason. Seems like they have their hands full with other kinds of destruction anyway lol

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