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Inflammation might be the root of preventable disease

harvardmagazine.com

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Re: Inflammation might be the root of preventable disease

#121

Post by zwkrt »

orangecat wrote: post #75
rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

What is your reaction when social conservatives say that there's no need for contraception or STD vaccines, because you can just not have sex unless you're prepared to accept the responsibilities of pregnancy and raising a child?

These two statements don't seem to have many analogies, why is this relevant?

Re: Inflammation might be the root of preventable disease

#122

Post by muvek »

BandOfBots wrote: post #111
rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

The most effective natural treatment for inflammation is 20 minutes a day in sauna

Source needed?

Re: Inflammation might be the root of preventable disease

#123

Post by andai »

User23 wrote: post #89
goldenkey wrote: post #55

Earlier quoted context omitted.

I think what they are referring to is molecules like Cytokines [1] which are found in responses to [infection, immune responses, inflammation, trauma, sepsis, cancer, and reproduction] (from Wikipedia) Inflammation and immune response seem entirely connected. [1] https://en.wikipedia.org/wiki/Cytokine

Don't forget exercise in that list.

Also digestion, depending on what you ate.

Re: Inflammation might be the root of preventable disease

#124

Post by braink »

rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

Bottom line: pharma sells pills to make money; they don't make money off of healthy people who don't take their pills. So long as we link the health industry to making profit, we are prioritizing profits over health.

Re: Inflammation might be the root of preventable disease

#125

Post by mikedilger »

That study they cite: 3 of 4 dose levels didn't meet the statistical significant threshold, and in the one that did there was no difference in all cause mortality.

Look, I wish it was as simple as a single easily treatable vector like inflammation. But it's not. Life is not simple.

Re: Inflammation might be the root of preventable disease

#126

Post by taneq »

zwkrt wrote: post #119
mleonhard wrote: post #116

Is this a PR piece paid for by Novartis, the makers of Canakinumab? Wikipedia says the drug costs $8k/week and the initial study showed no survival benefit. Then "further analysis" showed a big benefit. Something seems off. https://en.wikipedia.org/wiki/Canakinumab

Inflammation can also be heavily reduced for "free" with a lifestyle change though, so I'm not exactly buying it.

Yeah but who's going to do that?

Re: Inflammation might be the root of preventable disease

#128

Post by cellularmitosis »

muvek wrote: post #122
BandOfBots wrote: post #111

Earlier quoted context omitted.

The most effective natural treatment for inflammation is 20 minutes a day in sauna

Source needed?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941775/

> "It has been suggested that heat stress induces adaptive hormesis mechanisms similar to exercise, and there are reports of cellular effects induced by whole-body hyperthermia in conjunction with oncology-related interventions"

I wonder if the key is simply raising the temperature of the blood. My understanding is that processes like Regenokine extract your blood, elevate its temperature (which causes it to produce natural anti-inflammatory compounds?) and then inject it back into your body. Perhaps sauna (and exercise?) are doing the same, but to a lesser degree. https://en.wikipedia.org/wiki/Autologous_conditioned_serum

Re: Inflammation might be the root of preventable disease

#129

Post by _up »

LinuxBender wrote: post #6

In my case, inflammation is a side effect of insulin resistance, like my fellow 83 million Americans with metabolic syndrome. If I can reverse the cause long enough, the liver should stop dumping fat into the adipose tissue and triglycerides may drop.

I had the same problem and then started Keto/IF and also switched to better Oils (less Omega6)for cooking and also eat a can of cod liver (packaged less than 6 months before) which has lots of Omega3 and Vitamin A every two weeks. I have the feeling that everyone is different and there isn't one solution that works for everyone. But sugar, processed foods, and too much Omega6 are a big factor in a lot of illnesses.

Re: Inflammation might be the root of preventable disease

#130

Post by _up »

LinuxBender wrote: post #9
rq1 wrote: post #8

Earlier quoted context omitted.

Go for keto + IF. It helped a lot of people.

I did. In fact that was a great start, but once you reach a certain point (in having metabolic syndrome), the Keto+IF reaches diminishing returns. It did bring me down 18 inches on the waist. The gut and hypertension will remain. In fact, my hypertension actually went up. To go further requires either Metformin or Berberine. I opted for Berberine, but time will tell.

Did you take in enough Electrolytes? Like Salt, Potassium and Magnesium? Because you lose a lot of Water and Minerals when doing this diet.
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