>The farmers apparently take the drug themselves, at pretty high dosages, saying that it allows them to work without getting tiree. That's insane. Tramadol is among the worst painkillers to use recreationally, which is why it's often the next line of analgesic therapy after NSAIDs and before hydrocodone. It is a comparatively weak mu-opioid agonist, so the dose a person would have to take to get a prototypical opioid…
I just want to note that acetaminophen (paracetamol) is not an NSAID. As a haemophilia patient who can't take NSAIDs but can take acetaminophen, this is an important distinction for me.
Drugs company hates him! now seriously, where do one find such abundance of opiates to feed cows of?!
I'm not sure if you're joking, but opiates are grown from opium poppy plants, so that would be a good place to start if you actually wanted an abundance to feed to animals. Tramadol, however, is an opioid , which is a term that encompasses both opiates and synthetic opiate-like drugs -- of which Tramadol falls in the latter.
that's the point. synthetic opiates are not cheap. and those farmers are feeding herd with it.
Yeah yeah it's not 100% but it's still reasonably strong evidence. If you find something in a plant that's eaten by many things then it's probably not very toxic.
Maybe that's some evidence, but it's certainly not reasonably strong (in fact, it's very weak evidence). First, some of those "many things" would need to have a metabolism that's close to ours. Secondly, even if those unaffected organisms are similar to us, we would need to consume that molecule at similar concentrations. Most toxins have adverse effect only beyond a certain dosage. Something can be harmless (like cy…
'toxic' is a much weaker assertion than 'does batshit crazy things to life'
It's not as addictive as other opiates. It is physically addictive though, yes. Opiate withdrawals don't kill you, although you'll want to die; Tramadol has a weird secondary set of effects that act like an SSRI/anti-depressant, so you get both the opiate withdrawal symptoms as well as SSRI discontinuation syndrome symptoms which is a very unpleasant combination. It's a decent painkiller, but like any opiate based pa…
I think I read about seizures from cold turkey which required a 35 week long tapering schedule to avoid. Checking for a source I don't find this mentioned in official side-effects, only less formal guidance for addicts. Strange.
Seizures can also be caused in "overdose", which is unfortunately very very close to "recreational" doses. It's a very very weird drug in terms of secondary side-effects, the "SSRI" side can cause dangerous issues as well (serotonin toxicity when coupled with other serotonin affecting drugs).
It doesn't sound like they're trying to get high, per se, just work harder without feeling it. A "recreational" dose would probably interfere with getting work done.
Not necessarily. Opioids, like other euphoriants, are somewhat "stimulating" (mentally) in small doses. I know they aren't just "trying to get high". The problem is that in order to get any psychotropic effects from Tramadol, the dose is so high that a lot of other really nasty effects will come with it. A 5mg dose of hydrocodone would accomplish the effect they are after with very little negative physical effects. I…
You can't be serious. Are you advocating hydrocodone here which has one of the highest potential for debilitating addiction, so much so actually that it is banned in many countries and no longer available for medical use?
It doesn't sound like they're trying to get high, per se, just work harder without feeling it. A "recreational" dose would probably interfere with getting work done.
Not necessarily. Opioids, like other euphoriants, are somewhat "stimulating" (mentally) in small doses. I know they aren't just "trying to get high". The problem is that in order to get any psychotropic effects from Tramadol, the dose is so high that a lot of other really nasty effects will come with it. A 5mg dose of hydrocodone would accomplish the effect they are after with very little negative physical effects. I…
This is not entirely true. Tramadol are often given in doses of 3x50 mg a day for pain relief. To a user with no tolerance, the most common lowest dose, i.e. 1x50 mg is certainly more than enough to give a euphoric feeling, ability to concentrate, stress relief and a whole range of other effects. Effects obviously can't be compared to "real" opiates, where the effect is much stronger and have more of a sedative effect. It should also be noted the effects vary quite a bit depending on the individual, i.e. some people don't have much of a reaction to Tramadol.
Laboratory tests are expensive and time consuming and in this case completely unnecessary. Why would anyone do such an experiment?
Good point - as I said, I am not a scientist, so that's what I wanted to know and your answer helps me understand. In my mind, it seems like declaring that a plant is growing gold, without testing the ground (or doing a lab test), and later finding out that its roots are picking up the gold from a seam near the surface.
As an aside, carrots are a plant that takes up gold if given the oportunity.
Good point - as I said, I am not a scientist, so that's what I wanted to know and your answer helps me understand. In my mind, it seems like declaring that a plant is growing gold, without testing the ground (or doing a lab test), and later finding out that its roots are picking up the gold from a seam near the surface.
As an aside, carrots are a plant that takes up gold if given the oportunity.
Is there anywhere that one could read more about this?