Although it can really depend on who she gets. My wife came over to see me after I moved to the US after just losing our daughter. She had a 10-year multi-entry visa, had come and gone several times before. They held her for a couple of hours, went through all her stuff (which is to be expected), but then demanded to know why she was sad about losing a child, why she had written about her child if she had died, and on and on. My wife decided she'll never fly through the US again.
Once I got an agent, first thing out of his mouth was "you're going to miss your flight". When I said he didn't know when it was (I had a 3 hour layover), he said it didn't matter, he'd make sure. Other times, they barely even glance up and wave me through.