Live data from Hacker News

Anti-ageing compound set for human trials after turning clock back for mice

theguardian.com

111–120 of 243 posts

Re: Anti-ageing compound set for human trials after turning clock back for mice

#111
NAD is an interesting chemical anyway for its electrical properties. I had an idle thought once upon a time that you might be able to make some kind of liquid binary computer with it, given how readily you can “toggle” it between NAD+ and NADH. I don’t know nearly enough about it, though.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#112

Earlier quoted context omitted.

The flip side to that argument is that right now life is short, and so I try and fit as many wonderful experiences into it as I can. If life were long I could put everything off until tomorrow. And that doesn't sound good to me.

Are you really saying that you'd prefer to DIE in order to incent yourself to do exciting things sooner? Erm. Well, I guess that's one set of preferences.

There's a classic A Softer World comic that's been turned into a t-shirt that says "I would rather die screaming than live forever." There are downsides to the kind of extreme prudence that planning to be around for centuries would imply.

Also, there's a fantastic novel from Bruce Sterling called Holy Fire that is devoted to exploring the tension between living to continue living and living in the moment.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#113
post #85

Earlier quoted context omitted.

It's funny, I have a friend who is a full-time professional philosopher (teaches at a university) and you would not believe the amount of earnest essay writing there was in the philosophy community about Miley Cyrus's performance at the VMAs (something I've not actually seen myself). All sorts of theories about Freud and Hegel and this and that. Look Philos, I said to him, she got up on stage and did a little dance a…

More accurately, professional philosophers don't have any particular standing to discuss "serious philosophical issues." At any point in the discussion on whether people have a right to die, or whether it was ok to use tissue from aborted fetuses for stem cell research or whether we need universal health care, has anyone ever asked, "Well, what do the philosophers think?" (I have nothing against philosophers, btw. I…

You should live in france.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#114
post #37

Researchers injected a chemical called nicotinamide adenine dinucleotide, or NAD, which reduces in the body as we age. The addition of this compound led to the radical reversal in the ageing of the mice. While this is pretty cool, it seems that the most immediate effect would be a higher availability of adenosine triphosphate (ATP), meaning more energy "currency" for the body's machinery to work with [1] [2] (someone…

Ageing is a genetic disease. It has to be cured. We evolved to adapt to specific environment. Now that we are changing this environment we must change ourselves as well. Everyone should be given an option to die but it should be just one of a few options.

Indeed! Options like Death by My Little Pony:

http://www.fimfiction.net/story/62074/Friendship-is-Optimal

http://www.fimfiction.net/story/69770/friendship-is-optimal-...

Re: Anti-ageing compound set for human trials after turning clock back for mice

#115
post #28
post #17

Earlier quoted context omitted.

Rather selfish? We'll have enough problems in the coming decades with geriatric baby boomers, you now want to give people the option to live forever?

I have a hunch this is a technology that will take very long to 'trickle down' the forbes list.

I don't. An effective anti-aging treatment would likely pay for itself in Medicare savings alone.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#116
post #52
post #37

Researchers injected a chemical called nicotinamide adenine dinucleotide, or NAD, which reduces in the body as we age. The addition of this compound led to the radical reversal in the ageing of the mice. While this is pretty cool, it seems that the most immediate effect would be a higher availability of adenosine triphosphate (ATP), meaning more energy "currency" for the body's machinery to work with [1] [2] (someone…

This post fills me with questions. Foremost: What makes anti-aging technology unnatural compared to other medical treatments? To take one example, the smallpox vaccine was initially considered unnatural, and an affront to God[1]. [1] http://abob.libs.uga.edu/bobk/whitem10.html

"To take one example, the smallpox vaccine was initially considered unnatural, and an affront to God[1]."

In hell, conservatives will have the ability to turn off the flames.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#117
post #37

Researchers injected a chemical called nicotinamide adenine dinucleotide, or NAD, which reduces in the body as we age. The addition of this compound led to the radical reversal in the ageing of the mice. While this is pretty cool, it seems that the most immediate effect would be a higher availability of adenosine triphosphate (ATP), meaning more energy "currency" for the body's machinery to work with [1] [2] (someone…

Anti-aging has nothing more to do with immortality than does, say, curing a particular disease. Aging is only one of many causes of death; if we solve that one, there's still heart disease, stroke, getting hit by a bus...

Aubrey de Grey has said (as far as I know) that heart disease is a symptom of aging.

Re: Anti-ageing compound set for human trials after turning clock back for mice

#118
post #85

Earlier quoted context omitted.

“Personally, I’ve been hearing all my life about the Serious Philosophical Issues posed by life extension, and my attitude has always been that I’m willing to grapple with those issues for as many centuries as it takes.” -Patrick Hayden

It's funny, I have a friend who is a full-time professional philosopher (teaches at a university) and you would not believe the amount of earnest essay writing there was in the philosophy community about Miley Cyrus's performance at the VMAs (something I've not actually seen myself). All sorts of theories about Freud and Hegel and this and that. Look Philos, I said to him, she got up on stage and did a little dance a…

[deleted]

Re: Anti-ageing compound set for human trials after turning clock back for mice

#119
post #37

Researchers injected a chemical called nicotinamide adenine dinucleotide, or NAD, which reduces in the body as we age. The addition of this compound led to the radical reversal in the ageing of the mice. While this is pretty cool, it seems that the most immediate effect would be a higher availability of adenosine triphosphate (ATP), meaning more energy "currency" for the body's machinery to work with [1] [2] (someone…

> it seems that the most immediate effect would be a higher availability of adenosine triphosphate (ATP)

This study goes way over my head, but if the goal is to boost ATP isn't creatine monohydrate supplementation a cheap and effective way to do so currently?

Re: Anti-ageing compound set for human trials after turning clock back for mice

#120

Earlier quoted context omitted.

Ageing is a genetic disease. It has to be cured. We evolved to adapt to specific environment. Now that we are changing this environment we must change ourselves as well. Everyone should be given an option to die but it should be just one of a few options.

Indeed! Options like Death by My Little Pony: http://www.fimfiction.net/story/62074/Friendship-is-Optimal http://www.fimfiction.net/story/69770/friendship-is-optimal-...

[deleted]
Post reply on HN