Live data from Hacker News

GLP-1s are being linked to fewer serious infections, including TB

gizmodo.com

61–70 of 89 posts

Re: GLP-1s are being linked to fewer serious infections, including TB

#63

Earlier quoted context omitted.

Or having a lower % of body fat (within healthy limits) is the factor improving a better immune response?

It may be that those without repeated toxic caloric exposure allows the immune system to focus on other aspects.

> toxic caloric exposure

Is that a thing?

Re: GLP-1s are being linked to fewer serious infections, including TB

#66

Maybe being overweight is bad for the immune system

huge if true

That's a known fact. That's why the first thing doctors say to overweight people is to lose weight for pretty much any disease. Some get hurt and blame the doctors, which doesn't help them.

Re: GLP-1s are being linked to fewer serious infections, including TB

#67

I was at a hepatology meeting focussed on fatty liver a couple of years ago, where a well regarded head of hepatology at a major national quarternary referral centre, joked that we should be putting this in the water supply...

> we should be putting this in the water supply...

Talked to a physician last year who said the entire planet should be on GLP-1s.

Re: GLP-1s are being linked to fewer serious infections, including TB

#68
post #4

How expensive are GLP-1s again?

AU$140 (~US$100) per 4mg, which is approx one month, here.

AU$25 (~US$18), or AU$7.70 (~US$5.50) with a concession card if you qualify for subsidy.

If you're in Australia it's worth a chat with your GP rather than less regulated channels.

Re: GLP-1s are being linked to fewer serious infections, including TB

#69
post #34
post #22

Earlier quoted context omitted.

The benefit is probably from the removal of fat, not a direct antibacterial/antiviral effect. Fat plays a complex immunoregulatory role in human physiology: it down-regulates some pathways, while up-regulating others (notoriously, the production of IL6 is carried out, in part, by adipocytes). The overall effect of fat on the immune system, however, is negative: it tends to increase the chances of rheumatological diso…

How much of “fat” also includes biofilmed infection stifling your electrical system and indeed signaling your immune system to not work as well? (You can look this up regarding biofilms, I just did today.)

Then you must have some links available

Re: GLP-1s are being linked to fewer serious infections, including TB

#70
post #24

Earlier quoted context omitted.

I’m sure you can just look up the studies, but note that GLP1s are widely prescribed to people without weight issues —— weight loss itself was originally an off-target effect. I have friends who run marathons who are on semaglutide.

Because they need to medically or it helps athletically ?

Because they need it medically.
Post reply on HN