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Autism mutations drive neurodevelopmental pathology

science.org

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Re: Autism mutations drive neurodevelopmental pathology

#191

Post by wredcoll »

forestrywat wrote: post #151
wredcoll wrote: post #95

Earlier quoted context omitted.

> Have a disability" and "broken" are not synonyms They really are. Like, you can alter the environment all you want but someone who needs glasses to see has broken eyes. Is it super common and do we have a cure? Yes and yes, but it's still, you know, not working. Disabled. Busted. Broken. Whichever word you pick isn't going to change the reality.

"That person is disabled" and "that person is broken" fundamentally are different. You are supposed to fix broken things. We don't fix disabilities. We can support them, treat them, assist them. Yes, having a disability is hard. But the person is not broken.

> We don't fix disabilities

What? Why not?

Re: Autism mutations drive neurodevelopmental pathology

#192

Post by wredcoll »

1attice wrote: post #188
s1artibartfast wrote: post #186

Earlier quoted context omitted.

>No one deserves to be alone in the manner you describe Woosh.. they are describing your mindset. Writing off 98% of the population as potential friends or lovers.

So, you could form an intimate relationship with literally anyone on Earth? Good luck getting through just the first floor of your condo block. I haven't written anyone off, I just plain don't like most of them. Are you that different? Why do you assume my statement is a priori instead of an empirical observation? Is that how you think about your own preferences, or do you ever just kinda go "huh, I guess I really do…

> I haven't written anyone off, I just plain don't like most of them.

I'm not trying to convince you, but for anyone else reading this, especially if you're young, people are social creatures and being social will make your life better. It's frequently not easy, and often quite difficult, but so is doing 100 pushups or getting a phd or whatever. Being difficult is not the same as being bad for you.

There is a gigantic difference between "I talked to Jay and he told me he hated me and I was going to burn in hell so I decided I don't like him" and "I have decided that all normies/allistics/football fans/whatever are boring and I don't like them".

It's hard to describe the kind of mindset I'm talking about here in a YC textbox. I firmly believe that every person working at say, the checkout line in my local grocery store, know or have done genuinely interesting things and if you ask the right way, you can find those fascinating things.

That doesn't mean I actually talk to every person who rings up my groceries, or even most of them, frankly. I'm frequently tired and in an asocial mode. But there's a big difference between "I'm choosing not to interact with this person right now due to my own energy/preferences right now" and "this person is inherently bad".

> or do you ever just kinda go "huh, I guess I really don't like $thing?"

Not when "$thing" IS A GROUP OF PEOPLE.

Re: Autism mutations drive neurodevelopmental pathology

#193

Post by hoppp »

inigyou wrote: post #182
hoppp wrote: post #177

Earlier quoted context omitted.

Psychopath is not considered a neurotype

Why not? It obviously is one.

In some form yes, but a psychopath can be also autistic, dyslexic or neurotypical but psychopathy by itself is not considered a neurotype.

Re: Autism mutations drive neurodevelopmental pathology

#194

Post by forestrywat »

wredcoll wrote: post #191
forestrywat wrote: post #151

Earlier quoted context omitted.

"That person is disabled" and "that person is broken" fundamentally are different. You are supposed to fix broken things. We don't fix disabilities. We can support them, treat them, assist them. Yes, having a disability is hard. But the person is not broken.

> We don't fix disabilities What? Why not?

Some we can and do. But many are not things that can be.

Re: Autism mutations drive neurodevelopmental pathology

#197

Post by emptybits »

maddie0 wrote: post #40
emptybits wrote: post #13

Earlier quoted context omitted.

No need for your tag. The United States makes repeated claims linking childhood vaccines to autism. https://www.factcheck.org/2026/08/trump-and-rfk-jr-repeat-fa...

Come now! It is clear that the sarcasm indicator wasn't suggesting that the government didn't really announce that. The sarcasm was in the invocation of governmental authority, which is thereby implied to be ill-founded and not worth listening to.

Glad it was clear to you.

I felt it useful to provide a reliable source for such an outrageous national position. Lest some think it exaggeration or twisting of facts for humour or effect. It's not. Yikes. :-)

Re: Autism mutations drive neurodevelopmental pathology

#198

Post by StevenWaterman »

zogzha wrote: post #112
StevenWaterman wrote: post #98

Earlier quoted context omitted.

My understanding is that that's what makes it a disorder - that it's just a collection of symptoms that seem to appear together, rather than something with a known mechanism and cause

you’re thinking of “syndrome”

Ah! You're right, thanks for the correction. Cunningham's Law wins again.

Re: Autism mutations drive neurodevelopmental pathology

#199

Post by gignico »

maddie0 wrote: post #40
emptybits wrote: post #13

Earlier quoted context omitted.

No need for your tag. The United States makes repeated claims linking childhood vaccines to autism. https://www.factcheck.org/2026/08/trump-and-rfk-jr-repeat-fa...

Come now! It is clear that the sarcasm indicator wasn't suggesting that the government didn't really announce that. The sarcasm was in the invocation of governmental authority, which is thereby implied to be ill-founded and not worth listening to.

Indeed, thanks :)
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