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Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

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Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#11

Post by henry2023 »

MartinMond wrote: post #9

I listened to a great podcast on this just a month ago - too bad that I thought all of this would obviously be priced in already… https://virological.podigee.io/51-21-cancer-vaccines-how-the...

Even if you were to optimally price in all available information you still have uncertainty of what will actually happen. i.e. A 1 dollar coin flip has an expected value of 50c before it’s thrown and it will collapse either to zero or to one after the uncertainty is resolved.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#13

Post by Someone1234 »

reenorap wrote: post #12

[flagged]

> For all the hate I have for the COVID vaccine

Can you clarify that? It saved 100K+ lives even by incredibly conservative estimates, and allowed life to returned to normal at least a year earlier than otherwise.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#17

Post by Jyaif »

consumer451 wrote: post #8

This appears to be a potentially huge win for health. The market has Moderna up 153% at time of writing, which is some sort of validation I suppose. Related stories: https://www.fiercebiotech.com/biotech/merck-and-modernas-per... https://www.reuters.com/legal/litigation/merck-moderna-say-m... https://www.wsj.com/health/pharma/moderna-merck-vaccine-succ...

oh nice. If it goes up another 100% I may not lose money on this stock anymore.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#18

Post by Insanity »

declan_roberts wrote: post #15
bhaak wrote: post #14

Earlier quoted context omitted.

What are the reasons for the hate of the COVID vaccine?

Probably one of the most polarizing issues of the last 5 years.

I don't recall it being as polarizing outside of the US, where there was a larger group of anti-vaxxers to begin with. But that might be my "outside US" bubble.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#19

Post by declan_roberts »

Someone1234 wrote: post #13
reenorap wrote: post #12

[flagged]

> For all the hate I have for the COVID vaccine Can you clarify that? It saved 100K+ lives even by incredibly conservative estimates, and allowed life to returned to normal at least a year earlier than otherwise.

I can't speak for other people but I was upset to enter a medical era where bureaucrats were forcing medical decisions on me. I was forced to get it or lose my job despite 1) working remotely, 2) having already had Covid and 3) being healthy and not at risk of Covid death but being the largest risk for myocarditis.

Re: Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma

#20

Post by consumer451 »

Jyaif wrote: post #17
consumer451 wrote: post #8

This appears to be a potentially huge win for health. The market has Moderna up 153% at time of writing, which is some sort of validation I suppose. Related stories: https://www.fiercebiotech.com/biotech/merck-and-modernas-per... https://www.reuters.com/legal/litigation/merck-moderna-say-m... https://www.wsj.com/health/pharma/moderna-merck-vaccine-succ...

oh nice. If it goes up another 100% I may not lose money on this stock anymore.

I mean, this appears to be validation of mRNA in general, right?
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