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AI in drug discovery – what it is, where we stand and the path forward

science.org

41–50 of 105 posts

Re: AI in drug discovery – what it is, where we stand and the path forward

#41
post #33

need one for brain plasicity. it would be nice to be able to easily learn a foreign language or musical instrument naturally.

Easily? Have you ever actually learned a second language or an instrument as a child?

Vs as an adult. Yes it's hard as a kid, but as an adult it's even harder.

Re: AI in drug discovery – what it is, where we stand and the path forward

#42

nerd-fanboi proposal: Articles by national treasures (like Derek Lowe, Raymond Chen) should be highlighted with specific identifiers on HN - like a distinctive title font or an ascii diamond ◊.

No thanks. Social media needs less hero worship. Just RSS whoever you like.

Make the feature a per user list of flagged sources.

Re: AI in drug discovery – what it is, where we stand and the path forward

#43

nerd-fanboi proposal: Articles by national treasures (like Derek Lowe, Raymond Chen) should be highlighted with specific identifiers on HN - like a distinctive title font or an ascii diamond ◊.

No thanks. Social media needs less hero worship. Just RSS whoever you like.

I would have agreed in past, but the new random "blog" at whatever.etc being written by LLMs is making me skip clicking most links here now.

Re: AI in drug discovery – what it is, where we stand and the path forward

#44
post #30

Derek Lowe discusion of the paper https://www.science.org/content/blog-post/so-how-ai-drug-dis... I think that was originally linked but got changed to the £30 to Elsevier version for some reason.

Derek Lowe as a science communicator, and others like him, is sorely needed to understand the real meaning and significance of the study and others. I say that as someone with a PhD in chemistry who's been to plenty of presentations on drug discovery topics. It's difficult to calibrate statements made by other scientists unless you're well embedded within a field: Is this someone whose opinions matter? Are they the s…

Not that I'm a Derek Lowe fanboy or anything but the entirety of your comment is like "that guy needs to check himself" without, like, any specific context, any specific argument he's wrong on this specific question or like anything. It's like "deciphering questions around credibility" is hard ... all the way down. Where's yours? What are you saying?

Re: AI in drug discovery – what it is, where we stand and the path forward

#45

Earlier quoted context omitted.

Derek Lowe as a science communicator, and others like him, is sorely needed to understand the real meaning and significance of the study and others. I say that as someone with a PhD in chemistry who's been to plenty of presentations on drug discovery topics. It's difficult to calibrate statements made by other scientists unless you're well embedded within a field: Is this someone whose opinions matter? Are they the s…

Not that I'm a Derek Lowe fanboy or anything but the entirety of your comment is like "that guy needs to check himself" without, like, any specific context, any specific argument he's wrong on this specific question or like anything. It's like "deciphering questions around credibility" is hard ... all the way down. Where's yours? What are you saying?

Isn't the comment in fact praising Derek Lowe as a science communicator? In the second paragraph OP is just posing the questions that one might have when reading about a field not your own, that highlight the importance of reliable science communicators.

Re: AI in drug discovery – what it is, where we stand and the path forward

#48
I think the real win here is for idiots like me:

A) no education

B) no resources

C) not smart enough to be a self-taught bio-hacker

Everyone hears "AI is going to cure disease" and pictures some cure-all pill from a bio lab which is what I feel this paper is hinting at is missingb but that's the top of the funnel; I'm at the bottom where patients live and that is where AI is already quietly working. Its just not being benchmarked.

I built https://crohns.ai. I set out to make an AI-native clinical-trial manager with a feedback loop (DDP) and ended up somewhere completely different: instead of chasing a new "drug" which is totally out of my grasp; financially, intellectually etc... I used it to codify a care protocol that helped me avoid a flare after I got laid off, lost my insurance, and lost access to Skyrizi.

Re: AI in drug discovery – what it is, where we stand and the path forward

#49
post #45

Earlier quoted context omitted.

Not that I'm a Derek Lowe fanboy or anything but the entirety of your comment is like "that guy needs to check himself" without, like, any specific context, any specific argument he's wrong on this specific question or like anything. It's like "deciphering questions around credibility" is hard ... all the way down. Where's yours? What are you saying?

Isn't the comment in fact praising Derek Lowe as a science communicator? In the second paragraph OP is just posing the questions that one might have when reading about a field not your own, that highlight the importance of reliable science communicators.

It's a very confusing comment since Derek Lowe is a chemist working in pharma but is being referred to only as a science communicator which I suspect most people would consider to be an implicit insult.
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