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AI in drug discovery – what it is, where we stand and the path forward

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Re: AI in drug discovery – what it is, where we stand and the path forward

#22

need one for brain plasicity. it would be nice to be able to easily learn a foreign language or musical instrument naturally.

There is one!

Ketamin should have huge impacts on neuro/brain plasticity when used properly (i.e. in therapy)

Re: AI in drug discovery – what it is, where we stand and the path forward

#23

Need one for hair loss ASAP.

there is a AI designed drug for hair loss that i know of.

its slow-release oral minoxidil formulation called MINX. AI helped with the formulation [1].

its in in similar category as VDPHL01. Hundreds of millions if not a billion dollars has been invested into Veradermics, and their main product is VDPHL01 (also an extended-release oral formulation).

[1] https://x.com/anagenxyz/status/2071601868841595082

Re: AI in drug discovery – what it is, where we stand and the path forward

#24
post #16

Earlier quoted context omitted.

About 2% of finasteride users experience these side effects, and they are reversible after discontinuation.

Apparently some users report persistent side effects even years after stopping the medication (post-finasteride syndrome).

yep that would be me

Re: AI in drug discovery – what it is, where we stand and the path forward

#25
post #16

Earlier quoted context omitted.

About 2% of finasteride users experience these side effects, and they are reversible after discontinuation.

Apparently some users report persistent side effects even years after stopping the medication (post-finasteride syndrome).

How many of them can be accounted for by the natural rate of sexual dysfunction?

I've been taking it without significant side effects for ~15 years, so I'm not worried, although at this point it's losing its main effect as well.

Re: AI in drug discovery – what it is, where we stand and the path forward

#26

need one for brain plasicity. it would be nice to be able to easily learn a foreign language or musical instrument naturally.

There is one! Ketamin should have huge impacts on neuro/brain plasticity when used properly (i.e. in therapy)

Psychedelics are several orders of magnitude stronger on the plasticity front.

In therapy as well.

Re: AI in drug discovery – what it is, where we stand and the path forward

#28

Need one for hair loss ASAP.

there is a AI designed drug for hair loss that i know of. its slow-release oral minoxidil formulation called MINX. AI helped with the formulation [1]. its in in similar category as VDPHL01. Hundreds of millions if not a billion dollars has been invested into Veradermics, and their main product is VDPHL01 (also an extended-release oral formulation). [1] https://x.com/anagenxyz/status/2071601868841595082

I’m on 0.5 to 1mg oral minoxidil daily for a few years now and it’s working great. Blood pressure benefits too.

Re: AI in drug discovery – what it is, where we stand and the path forward

#29

need one for brain plasicity. it would be nice to be able to easily learn a foreign language or musical instrument naturally.

Psilocybin has this effect. Source: I can't remember where I read it, so low confidence.
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