Absolutely magical drug ! It makes you thinner, younger and now smarter !
Semaglutide linked to lower predicted dementia risk
21–30 of 430 posts
Re: Semaglutide linked to lower predicted dementia risk
#22Earlier quoted context omitted.
Western disease and sugar heavy diets broadly speaking, which Semaglutide is a countermeasure against. Not yet a vaccine, but in due time (probably via gene therapy). Fructose also helps cancer metastases and spread. https://www.sciencealert.com/common-sugar-appears-to-loosen-...
> Western disease and sugar heavy diets broadly speaking No, just being sedentary. There's no such thing as acquired diabetes in physically active people.
Doubt you can eat just pure fructose for 30 years and ”move” and avoid diabetes.
Re: Semaglutide linked to lower predicted dementia risk
#23So has anyone managed to separate the effects of semaglutide from the effects of weight loss?
If this is caused by the weight loss, it is a little disappointing that public health didn't act quicker - lots of people have been overweight for a century now, so literally 10's of millions of people could have been saved from dementia had action been taken 100 years ago.
Re: Semaglutide linked to lower predicted dementia risk
#24If you're overweight or especially if you're T2D I highly encourage you to discuss GLP-1 with your doctor. If you're T2D then get research retatrutide which looks to be an actual cure for T2D by clearing liver fat. It should be released early next year but research-use is available and what everybody is taking. Companies like finnrick do public testing of research peptides and a good place to gather names.
Re: Semaglutide linked to lower predicted dementia risk
#25"Semaglutide attenuates a proteomics-based dementia risk signature " ie : clinically meaningless. The company behind this, Novo Nordisk is increasingly desperate, as tirzepatide destroys the semaglutide revenue stream and the consequent job losses decimate the company
Their operating profit was up 11% on a margin of 44% according to their recent quarterly release, and they beat EPS by 23%. They were in a little trouble in the stock market a few years ago as competitors came online, but they are doing pretty well right now.
They have launched new semaglutide oral products which are growing faster than previous products, and they have multiple drugs in the research pipeline in late phases.
Re: Semaglutide linked to lower predicted dementia risk
#26Earlier quoted context omitted.
For sure we still need to find out many related outcomes. Last year it become known that it increases (high relative risk, low absolute risk) non-arteritic anterior ischemic optic neuropathy (NAION), ie sudden, sometimes permanent vision loss. https://www.ema.europa.eu/en/news/prac-concludes-eye-conditi...
To save others the click: It increased the likelihood to 1 in 10,000 in adults with type 2 diabetes. Diabetics are already more prone NAION. This studies contribution was to show that diabetics on GLP-1's are MORE prone. It does not show that the general population is more prone when taking GLP-1's. I didn't check to see if other studies prove that.
It's also true that having a crowded optical disc is pretty much a required precursor condition to suffering NAION.
Which you can get checked for via a $50 optical scan.
No crowded disc, very little risk.
(Cup to Disc ratio of 0.2ish or less starts to present risk)
Re: Semaglutide linked to lower predicted dementia risk
#27If you're overweight or especially if you're T2D I highly encourage you to discuss GLP-1 with your doctor. If you're T2D then get research retatrutide which looks to be an actual cure for T2D by clearing liver fat. It should be released early next year but research-use is available and what everybody is taking. Companies like finnrick do public testing of research peptides and a good place to gather names.
Semaglutide cleared my liver fat and fixed my moderate NAFLD in a matter of months. Why is retatrutide necessary?
Re: Semaglutide linked to lower predicted dementia risk
#28Although it's encouraging, they do mention that the reduction in the BMI also have an effect (they take it into the consideration by lowering the β −0.092 to β −0.066 (P Just skimming through it, it's possible there are direct benefits, but it could also be other environmental factor. This study will most likely generate others that give us more insight in the future.
Re: Semaglutide linked to lower predicted dementia risk
#29Earlier quoted context omitted.
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Just pattern matching as an autistic human. Similar results were seen on a ketogenic diet (and to some extent, intermittent fasting). What do they have in common? Sugar intake reduction. Is it surprising sugar potentially fuels cancer, contributes to dementia, etc? It shouldn’t be. It’s indirect and a casual connection. There is no health benefit to a high sugar or Western diet, only downside. I think calling it pois…
Thats due to caloric restriction. A high fat diet isn't going to helpful as well. To think that people cut sugar but continue to eat far too much meat and fat... yikes.
Re: Semaglutide linked to lower predicted dementia risk
#30If you're overweight or especially if you're T2D I highly encourage you to discuss GLP-1 with your doctor. If you're T2D then get research retatrutide which looks to be an actual cure for T2D by clearing liver fat. It should be released early next year but research-use is available and what everybody is taking. Companies like finnrick do public testing of research peptides and a good place to gather names.
Semaglutide cleared my liver fat and fixed my moderate NAFLD in a matter of months. Why is retatrutide necessary?
Semaglutide clears liver fat? I had no idea. I’m curious to know more about your protocol