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Drug reverses autism-like brain changes in adult mice within hours

uclahealth.org

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Re: Drug reverses autism-like brain changes in adult mice within hours

#41
post #31

Earlier quoted context omitted.

That may be what was meant, but that's not how it was written.

It was written fine. ASD is a disorder which was the first item on that list. You could make the same type of argument about disabilities (e.g. deafness) and someone pointed out that people make the same arguments in the deaf community too.

Words mean things.

Re: Drug reverses autism-like brain changes in adult mice within hours

#42
post #41

Earlier quoted context omitted.

It was written fine. ASD is a disorder which was the first item on that list. You could make the same type of argument about disabilities (e.g. deafness) and someone pointed out that people make the same arguments in the deaf community too.

Words mean things.

And my words in no way implied that those were equal, or that autism was necessarily an illness or a disability. People often make those arguments and I'm not one of them. You're attacking a straw man.

Re: Drug reverses autism-like brain changes in adult mice within hours

#43

Earlier quoted context omitted.

I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses? You could make the exact same arguments for blindness. Every day is challenging, difficulties are mostly a consequence of how we've structured society, it's other people who should accommodate those who have different needs, etc. This narrative seems to originate from, and is perpetuated…

> How is this different from other disorders, disabilities, illnesses? Not diagnosed autistic myself, but I buy into the argument that a lot of “(mental) disorders” make one allergic to the amount of subtle and less subtle daily dose of interrelational violence. Plenty of drugs exist to numb organisms. I don’t know if you’ve ever been on antidepressants or antipsychotics, but one who has might relate that that kind o…

[dead]

Re: Drug reverses autism-like brain changes in adult mice within hours

#44
post #28

Earlier quoted context omitted.

Would we have evidence even if it was true?

What do you mean? Population control?

Has anyone done an experiment administering rapamycin to humans to see if it slows aging? Would that experiment pass an ethics committee?

Re: Drug reverses autism-like brain changes in adult mice within hours

#45

Being autistic myself, I feel conflicted about trying to "cure autism" Every day is challenging because I have to manage my energy, mask in social situations and at work, etc On the other hand, I like who I am and I'm also very good at what I do because my brain is structured the way it is. I can imagine a society that is structured in a way, where I don't need the accommodations I'm currently dependent on If the neg…

I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses? You could make the exact same arguments for blindness. Every day is challenging, difficulties are mostly a consequence of how we've structured society, it's other people who should accommodate those who have different needs, etc. This narrative seems to originate from, and is perpetuated…

Spot on.

The same arguments pop up when new therapies are unveiled for various sightedness disorders, hearing impairment, etc.

How _dare_ you impugn upon my identity that has been reinforced through my upbringing constantly? Etc.

Re: Drug reverses autism-like brain changes in adult mice within hours

#46
post #41

Earlier quoted context omitted.

Words mean things.

And my words in no way implied that those were equal, or that autism was necessarily an illness or a disability. People often make those arguments and I'm not one of them. You're attacking a straw man.

sigh.

> I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses?

We have a comparative question involving a list of things, here.

Let's unroll the list and make separate comparative questions instead:

  autism. How is this different from other disorders?
This works. Autism is a disorder. It can be compared to other disorders.

  autism. How is this different from other disabilities?
This doesn't work. The comparison rests upon the implication that autism must be a disability, but that's just not absolute. It certainly can be disabling, but it often is not disabling.

  autism. How is this different from other illnesses?
This doesn't work. Autism is not an illness.

Re: Drug reverses autism-like brain changes in adult mice within hours

#47
post #26

Earlier quoted context omitted.

I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses? You could make the exact same arguments for blindness. Every day is challenging, difficulties are mostly a consequence of how we've structured society, it's other people who should accommodate those who have different needs, etc. This narrative seems to originate from, and is perpetuated…

It isn't unique. Deaf people fight against research to cure hearing loss and fight against people having it cured, as they say it's betraying the deaf community.

Fortunately most of their criticism falls on deaf ears.

Re: Drug reverses autism-like brain changes in adult mice within hours

#48
post #46

Earlier quoted context omitted.

And my words in no way implied that those were equal, or that autism was necessarily an illness or a disability. People often make those arguments and I'm not one of them. You're attacking a straw man.

sigh. > I see this sentiment often, but only when it comes to autism. How is this different from other disorders, disabilities, illnesses? We have a comparative question involving a list of things, here. Let's unroll the list and make separate comparative questions instead: autism. How is this different from other disorders? This works. Autism is a disorder. It can be compared to other disorders. autism. How is this…

I suggest going for the most charitable interpretation of OPs writing. This is isn’t it.

Re: Drug reverses autism-like brain changes in adult mice within hours

#49
post #44

Earlier quoted context omitted.

What do you mean? Population control?

Has anyone done an experiment administering rapamycin to humans to see if it slows aging? Would that experiment pass an ethics committee?

We don't even have reliable biomarkers for aging in general so what would the endpoints for such an experiment be?

Re: Drug reverses autism-like brain changes in adult mice within hours

#50

Earlier quoted context omitted.

> How is this different from other disorders, disabilities, illnesses? Part of the confusion here is that autism isn't straightforwardly a disability. A plurality of people with autism are ASD-1, which is the kind requiring the least support needs while, purely empirically speaking, conferring lots of well-documented benefits. The sort of elephant in the room in these conversations is that there are lots of replicabl…

I agree up until this point: > The idea of attempting to engineer the removal of a class of people from society-- people with unique strengths which are necessary for the functioning of that society-- has consequences that are significantly less well-understood than proponents of this idea make it out to be. I'll be the first to pick up my pitchforks at anyone who suggests non-consensual treatments. My point is that…

You don't need a big bad government or other outside entity to have non-consensual treatments. Just make it available to parents, who can make decisions for their children regardless of their wishes or any nuances of the situation. They won't allow kids to grow up and choose for themselves.

Does being autistic decrease your chances of finding a partner? That feels like something that should be substantiated, because although it feels logical that a deficiency in communication would lead to this, in reality I just see autistic people seeking each other explicitly or even subconsciously by being inclined toward their own traits.

I think a stronger argument is that there are more severe instances of autism that are disabling while providing few benefits of 'mild' or 'normal' autism.

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