Earlier quoted context omitted.
I know a lot more about chemistry and physics than I know about biology, so biological risk is still at least a "maybe" reason to be worried about model safety for me. I don't worry about other weapons of mass destruction developed with LLM assistance. Nuclear weapons are already controlled much more with political pressure and the physical difficulty of e.g. enriching uranium than they are controlled by secret-keepi…
> For all I know (I don't know a lot about biology), it's possible to develop a virus that spreads as easily as measles, but has the lethality and long induction period of HIV. If that's true, and if LLMs would make it easy to develop such a virus, I see how no-guardrails LLMs could be truly disastrous. This is the specific example in the latest doomerist wave I have so much trouble with: by what mechanism is an LLM…
Opus 4.8 was the first model that could plausibly roleplay a BJJ roll without making a physically implausible move within five conversational turns. Fable 5 was the first model that beat me at the task, where I was the first party to write down an implausible move.