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How to sequence your own DNA at home

bradleywoolf.com

101–110 of 161 posts

Re: How to sequence your own DNA at home

#101

I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.

If a service doesn't give you the raw data for some reason you should be able to get it with a GDPR subject access request.

Re: How to sequence your own DNA at home

#102

Can CRISPR also be done at home this cheaply? Seems like maybe of the 3 dystopias: AI, Global Warming, Bio-warfare. That this is demonstrating that the home grown virus is closer than we think.

yes https://www.the-odin.com/blog/how-to-do-crispr-at-home-begin...

Re: How to sequence your own DNA at home

#103

> This is intended to be read by AI- please just copy and paste the URL of this and have ChatGPT walk you through it. If you have AR glasses, even better, since the AI can walk you through the whole protocol. What kind of magic is going on here, am I missing something?

I feel it's actually kind of smart. Most people won't be reading the blog post themselves, they'd ask GPT to understand the text and fetch the summary or whatever is relevant to them. The author has directly made the resource such that it is optimised for the output after that mostly-everyone-would-do-this step.

> Most people won't be reading the blog post themselves, they'd ask GPT to understand the text and fetch the summary or whatever is relevant to them.

What a sad reality we live in. Or to quote C3PO from Star Wars 2... "Machines building machines. How perverse.".

Re: How to sequence your own DNA at home

#104

I've bee thinking about starting a company where I fish roots out of your sewer and identify the plant (by sequence if necessary) that you have to kill so your sewer doesn't collapse as soon as it otherwise would. $100 to stave off that $10000 sewer replacement for a few years would be worth it to a lot of people

That’s a really clever idea, I would definitely pay for that in the right circumstances. Now that I think about it - could you just pour some sort of biodegradable broad-spectrum herbicide down the drain to get the same effect for cheaper?

> could you just pour some sort of biodegradable broad-spectrum herbicide down the drain to get the same effect for cheaper?

It will not degrade anywhere near fast enough to not cause serious issues in the biological treatment stage of the wastewater plant.

Re: How to sequence your own DNA at home

#105
It might make even more sense once we get to the point of a wider use of encoding the data into dna. For now we have these few commercial players in the field that cad do it (eg look up dna microfactory for storage archiving), IIRC genomika was saying they can do an MB for a 100-200eur.

Re: How to sequence your own DNA at home

#106
post #87

Earlier quoted context omitted.

Sequencing dot com. TellmeGen DNA Complete. Unless you live in Germany (in Germany it seems to be illegal to send saliva to other countries).

Can you get raw data from Tellmegen? Can't seem to find any info on this on their website.

Yes, it is in profile/settings.

Re: How to sequence your own DNA at home

#107

I've bee thinking about starting a company where I fish roots out of your sewer and identify the plant (by sequence if necessary) that you have to kill so your sewer doesn't collapse as soon as it otherwise would. $100 to stave off that $10000 sewer replacement for a few years would be worth it to a lot of people

https://www.envirodna.com/

https://www.naturemetrics.com/species-detection

https://www.ednacollab.org/industry/

https://wilderlab.co/

These companies focus on environmental DNA - some are more on the level of local government monitoring, some are for private customers.

Re: How to sequence your own DNA at home

#108
post #76

Earlier quoted context omitted.

Sequencing dot com. TellmeGen DNA Complete. Unless you live in Germany (in Germany it seems to be illegal to send saliva to other countries).

TellMeGen has a lifelong update, I guess they store your data to do that.

What does "lifelong update" mean in this context? are they not doing whole genome sequencing to begin with?

Re: How to sequence your own DNA at home

#109

I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.

I want long-read raw data. Also Europe (Germany) and simple consumer. Is there any third-party service that offers this? How much will it cost me?

Why must it be long-read? The info I want is from nearly identical duplicated genes. I have FASTQ and BAM files from Dante Labs, but wasn't able to get the info I want out of them.

Re: How to sequence your own DNA at home

#110
post #76

Earlier quoted context omitted.

TellMeGen has a lifelong update, I guess they store your data to do that.

What does "lifelong update" mean in this context? are they not doing whole genome sequencing to begin with?

Seems like if new studies find a link between genes and diseases they would update the result of your gene based health risks.
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