101–110 of 136 posts
This is, I am assuming from the context, not opporating under the assumption PTSD often is rooted in brain damage from exposure to shockwaves.
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PTSD doesn't have anything to do with brain damage. PTSD is a trauma response. Are you thinking of TBI? TBI is a cumulative impact of small and large head trauma.
Nope - I mean PTSD. there is a growing body of evidence that PTSD may be caused (In many of most or the diagnosed cases) by concussions causing brain damage. This manifests from either enemy munitions, or the shock wave from your own artillery, explosives, or large-caliber weapons. The WWI name of "shell shock" describing the same phenomenon was probably more accurate than "PTSD".
I always wonder why ECT doesn't get more press. It very very often works on depression (and bipolar disorder, catatonia; anything affective-related really), although the effects may wane over time when the treatment is discontinued. Memory loss is one of the side effects, and it could actually be beneficial here.
It's strange how much attention novel psychedelic treatments get compared with older, less glamorous interventions that already help a lot of people
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This is nuts. Bringing ECT into the discussion of a novel psychedelic medicine. Totally different ballparks. Well-established results vs. very little formal research. Have you had ECT, or do you know anyone who has? It's a last resort for horrible depression and not much else. It has huge risks, and while it does often make these people's lives manageable, it shouldn't be in the same discussion as a medication that's…
I do wonder how many more people would be open to ECT if instead of using the electrical pulse we would give people some drug that causes a brief seizure. Right after the anesthesia, of course, just like now - but there's no electricity involved. I don't even know if such a safe drug exists.
Also https://en.wikipedia.org/wiki/Insulin_shock_therapy which used hypoglycaemic shocks rather than seizures.
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Saliva divinorum is inherently dysphoric due to its agonism of the kappa opiod receptor. For a different cheap legal drug that affects serotonin and the NMDA receptors like ibogaine does, there's always off label use of dextromethorphan (cough medicine)!
DXM is also the active ingredient in the antidepressant Auvelity (combined with bupropion) Lot of interesting studies and anecdotes on its efficacy as an antidepressant
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You are completely wrong. Its kinda scary how confident you are in your misunderstanding.
Is this pair of sentences indented to be satirical?
Roe Jogan, senior pharma correspondent at the BBC
I always wonder why ECT doesn't get more press. It very very often works on depression (and bipolar disorder, catatonia; anything affective-related really), although the effects may wane over time when the treatment is discontinued. Memory loss is one of the side effects, and it could actually be beneficial here.
Anecdotal, but I had a friend who had ECT for their depressive symptoms. They ended their life a few years afterwards. So no, ”very often works on depression” is not a characterization I would use.
I'm (genuinely) sorry about your friend, and I don't deny that it's worth sharing these anecdotes. But a single anecdote comes nowhere near refuting the claim that ECT very often works on depression.
The current state of scientific knowledge seems to be that it does very often "work", at least as a fast-acting short-term treatment for very severe depression.