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The main thing about P2P meth is that there's so much of it (2021)

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Re: The main thing about P2P meth is that there's so much of it (2021)

#261

Post by AnthonBerg »

jazzyjackson wrote: post #250
AnthonBerg wrote: post #224

Earlier quoted context omitted.

Nothing and everything: https://www.frontiersin.org/journals/immunology/articles/10.... (This is a serious article by a serious researcher. There exists good work on Frontiers in… .) The 5-HT2A receptor is profoundly immunomodulatory. (Acid is arguably a more potent immunomodulator – an antiinflammatory one – than it is psychoactive.) Local inflammation is a thing in injury, "global" inflammation as well – there is s…

huh. glad I asked.

I was quite surprised to find that paper! Thank you for… the audience?, for your consideration? It's quietly somewhat maddening that this is on the books and there's so little mention of it.

Like, psychedelics? I'm not a hippie. I'm not into psychedelics. I'm into neuroinflammation, haha

Re: The main thing about P2P meth is that there's so much of it (2021)

#262

Post by lobf »

jjfoooo4 wrote: post #235
AnthonyMouse wrote: post #219

Earlier quoted context omitted.

> Famously, the US spent about 15-20 years attempting this with opioids. They were widely available to people via a pseudo-medical process, or via secondhand dealing. Opioids were/are manufactured by regulated, publicly traded companies with inspectors who controlled purity and production. There is a pretty decent argument that this was still a result of pseudo-prohibition, which goes like this: Opioids were easy to…

Surely both manufacturer and convenience store have incentive to push the addictive product in this scenario. In any case, drug dealers really don’t need to do any pushing, the drugs sell themselves. Have you ever taken an opioid? The idea that unfettered access would result in less addiction and death is a pretty remarkable POV

>The idea that unfettered access would result in less addiction and death is a pretty remarkable POV

It's not that crazy, but it has to be coupled with accessible recovery programs. The classic tale (one that people in my life have gone through) is the prescribed opiates -> street heroin when the scrip runs out / when they change the oxy recipe so that it doesn't dissolve in water anymore so you can't shoot it.

This is obviously much more dangerous than getting oxy from your doctor, so the logic of "keep people from seeking heroin on the street" actually does make sense to me from a public health perspective.

Re: The main thing about P2P meth is that there's so much of it (2021)

#263

Post by solumunus »

stymaar wrote: post #157
hash872 wrote: post #34

Earlier quoted context omitted.

>The government should just regulate it, control purity and production and let people access small amounts for recreation/performance Famously, the US spent about 15-20 years attempting this with opioids. They were widely available to people via a pseudo-medical process, or via secondhand dealing. Opioids were/are manufactured by regulated, publicly traded companies with inspectors who controlled purity and productio…

WTF. This is complete nonsense. Opioids have never been made legal for recreational purpose. They were sold as painkillers by pharma corporations lying about their addictive effects and promoted through marketing campaign targeting doctors to prescribe them. I has nothing to do with the topic of recreational drugs.

Do you think opioids have been illegal for eternity?

Re: The main thing about P2P meth is that there's so much of it (2021)

#264

Post by nonameiguess »

fc417fc802 wrote: post #164
ptrl600 wrote: post #142

Earlier quoted context omitted.

Losing 5 pounds a month, 20 down and 10 to go.

Do I understand correctly that you're using it as an appetite suppressant? How effective has it been for you? Particularly considering that you're already drinking coffee and I would have expected caffeine to have the stronger effect there. Also out of curiosity why not go with one of the new peptides?

Ephedrine is a far stronger appetite suppressant than caffeine. It only has a six-hour half life, though. The classic bodybuilder ECA stack was typically taken every four hours, but I suppose it's quite a bit harder to get to 4% bodyfat than it is just to not be overweight.

Re: The main thing about P2P meth is that there's so much of it (2021)

#265

Post by cucumber3732842 »

hash872 wrote: post #34
keepamovin wrote: post #10

The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…

>The government should just regulate it, control purity and production and let people access small amounts for recreation/performance Famously, the US spent about 15-20 years attempting this with opioids. They were widely available to people via a pseudo-medical process, or via secondhand dealing. Opioids were/are manufactured by regulated, publicly traded companies with inspectors who controlled purity and productio…

In low doses most hard drugs that are uppers are pretty decent performance enhancing drugs. It's dumb that society can't get energy drinks and stuff with "low enough you can't realistically abuse them because you'll spend too much time going to piss" amounts of cocaine, amphetamines, etc.

Re: The main thing about P2P meth is that there's so much of it (2021)

#266

Post by cyberpunk »

CuriouslyC wrote: post #188
cyberpunk wrote: post #139

Earlier quoted context omitted.

The world would unambiguously be better off without alcohol.

Tell me you have/had an alcoholic parent without telling me.

Nope, parents didn’t drink either; but you do you.

Perhaps you’d be able to cope with life better if you weren’t so dependant on self medicating with harmful intoxicants and threatened by any statements against them.

Re: The main thing about P2P meth is that there's so much of it (2021)

#267

Post by cindyllm »

cucumber3732842 wrote: post #265
hash872 wrote: post #34

Earlier quoted context omitted.

>The government should just regulate it, control purity and production and let people access small amounts for recreation/performance Famously, the US spent about 15-20 years attempting this with opioids. They were widely available to people via a pseudo-medical process, or via secondhand dealing. Opioids were/are manufactured by regulated, publicly traded companies with inspectors who controlled purity and productio…

In low doses most hard drugs that are uppers are pretty decent performance enhancing drugs. It's dumb that society can't get energy drinks and stuff with "low enough you can't realistically abuse them because you'll spend too much time going to piss" amounts of cocaine, amphetamines, etc.

[dead]

Re: The main thing about P2P meth is that there's so much of it (2021)

#268

Post by whimsicalism »

keepamovin wrote: post #243
whimsicalism wrote: post #194

Earlier quoted context omitted.

what? their take directly contradicts what you said and supports the original article.

Noo, swim is saying the articles are not strong, but the street speaks in alignment with me I get why you’d take it the other way tho

i encourage you to read it again. the “atlantic article” refers to the original article that both this post and nswango are critiquing

Re: The main thing about P2P meth is that there's so much of it (2021)

#269

Post by phatskat »

sleight42 wrote: post #215
hash872 wrote: post #34

Earlier quoted context omitted.

>The government should just regulate it, control purity and production and let people access small amounts for recreation/performance Famously, the US spent about 15-20 years attempting this with opioids. They were widely available to people via a pseudo-medical process, or via secondhand dealing. Opioids were/are manufactured by regulated, publicly traded companies with inspectors who controlled purity and productio…

I wonder what sort of environment and conditions contribute to large populations seeking to use opioids in the first place? Theory: this is a socioeconomic problem rather than a public health problem. Our systems care too little for people. The easiest solution then is for people to self-medicate. It's easier to deny people a harmful salve that they feel they need than to provide them the social supports that they de…

100%

Drugs are an alluring and easy avenue for people who have a difficult time fitting into their social expectations and dealing with pressures. Obviously this isn’t where it starts, but treatment is so difficult and the punitive effects are so harsh that it creates a system that’s incredibly difficult to get out of…so why would you?

This isn’t always the case, of course, but my own anecdote:

My best friend in high school got hooked on heroin - not sure exactly what started him on it or why, but I could tell that he knew he didn’t want to be in that place, and that he as genuinely trying to get clean but the resources were limited and often harsh.

He did get clean for a while and applied for a job at Walmart - this kid was stupid smart, we’d do EE and programming projects all the time and I always felt like he was miles ahead of my understanding of technology - but this was what he had available because of his history.

The Walmart drug test popped for the drugs he was using _to get clean_ and they denied his application. Went home, relapsed, got found dead by his mother. It’s awful.

Re: The main thing about P2P meth is that there's so much of it (2021)

#270

Post by wutwutwat »

hash872 wrote: post #34
keepamovin wrote: post #10

The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…

>The government should just regulate it, control purity and production and let people access small amounts for recreation/performance Famously, the US spent about 15-20 years attempting this with opioids. They were widely available to people via a pseudo-medical process, or via secondhand dealing. Opioids were/are manufactured by regulated, publicly traded companies with inspectors who controlled purity and productio…

Look at alcohol. How many lives are negatively affected because of alcohol being freely available? By numbers alone when something is legal there are people who will participate who would otherwise never go near it if it were illegal. We're seeing this with weed right now imo.

Because it's legal, people will try it. And because we live in a country where it is celebrated, encouraged, and every holiday seems to be an excuse for folks to get hammered, A LOT of people will try it. How many would never touch it if it were illegal? How many wouldn't drink and drive and kill themselves? How many innocent people in the other car, completely sober, would still be here? Because remember, booze, or drugs in general, impact more than just the user. Their families, friends, and other random people can be impacted. How many kids grow up with a drunk parent, unable to properly express or process emotions, might not have to grow up unable to maintain healthy friendships because they don't know what they look like, or won't be taken advantage of because they have a caretaker/fixer mentality because that's what they had to do as a kid.

We know making booze illegal doesn't work, and that's not what I'm suggesting here. I'm not even suggesting anything. I'm just saying, the blast radius of booze impacts a lot of people beyond the alcoholic, and statistically, a portion of those lives negatively impacted are the direct result of alcohol being legal. I can speak from firsthand experience the impact of an alcoholic single parent growing up, which would be the reason I look at this topic the way I do. Would I have been given a more healthy and "normal" childhood had booze been illegal? Idk. But some kid out there would have, which might be all that matters.

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