There is a correlation between P2P meth and increased occurrences of meth psychosis that should be studied. It's a pretty consistent phenomenon
The main thing about P2P meth is that there's so much of it (2021)
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Re: The main thing about P2P meth is that there's so much of it (2021)
#242The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…
> All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The article addresses this: > Second, the evidence we have is against the idea of contaminants in P2P meth. Almost all meth was produced using P2P since 2012, before most reports of schizophrenia. And P2P meth synthesis has changed se…
Yeah, I just don’t think that’s very strong. The immediate precursor may not be the issue but the residues of routes to get to that precursor and what that precursor is contaminated with etc. that’s my point.
Re: The main thing about P2P meth is that there's so much of it (2021)
#243Earlier quoted context omitted.
I really appreciate your take. I think it is correct and reads as accurate. Clearly a batch problem. Also, I'm glad that the read from someone who's been in the trenches and on the ground about this issue is alignment with mine. Thanks for sharing on this thread
what? their take directly contradicts what you said and supports the original article.
Noo, swim is saying the articles are not strong, but the street speaks in alignment with me
I get why you’d take it the other way tho
Re: The main thing about P2P meth is that there's so much of it (2021)
#244The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…
Regular amphetamine (speed) is relatively okay as long as you’re not one of the people who’s wired to absolutely love it and develop a problem with it. Meth on the other hand really is quite nasty, it’s directly neurotoxic to dopamine neurons in a way that regular speed isn’t
Interesting. Any studies that slam dunk it?
Re: The main thing about P2P meth is that there's so much of it (2021)
#245The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…
Government does sorta regulate it. Desoxyn is (rarely) prescribed for ADHD when other meds aren't effective enough. The difference between most amphetamines and Desoxyn is that extra methyl group. That methyl group helps it cross the blood-brain barrier a little faster but the chemical that reaches the brain is the same in both cases.
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Re: The main thing about P2P meth is that there's so much of it (2021)
#246The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…
Do you have any memories that you cannot let go of? That play back in your head incessantly every single day without fail? That obsess nearly every waking moment? For addicts, that memory is the dopamine release of being high, and it definitely can happen after a single use. It doesn’t impress everyone in the same way, but for those who are vulnerable to it, it becomes nearly the only thought they can have until they…
Hmm, i get why you’d reach that conclusion with your experience, but i dispute that given the same experience only that conclusion is valid.
The “super addict edge case” is a problem but the good of the many outweighs the good of the few. Don’t discard, but manage. I believe access to drugs should be psych/(genetic if reliable)/“allergy type”/behavior tested. I won’t give you salvia if you will flip out per tests, but if you’re okay, you’re green.
The advantage of state controlled access is that you can actually achieve that, in theory. Promoting the thing you’re against rn might actually help reduce the harm you want to remove.
Re: The main thing about P2P meth is that there's so much of it (2021)
#247The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…
It's a pretty bad drug, I can see only disadvantages over plain amphetamine. If amphetamine isn't strong enough, you already have a serious problem. I'm not saying that criminalization is the right way, just that I don't see a responsible recreational/performance use for methamphetamine. It's too strong and too toxic. The regulation should permit only use for addiction management imho. Also, the long history is not e…
Not saying the risk profiles are the same, but some of the perception of different danger might be psychosocial normative informed by the differing criminalization. Plausible at least no? Important to keep that in mind.
Re: The main thing about P2P meth is that there's so much of it (2021)
#248And I thought for a second they were talking about peer to peer meth but no that's what the DEA shut down by tightly controlling pseudoephedrine, where before meth using meth makers were making meth and distributing it. It certainly seems like prohibition is just making things worse and making it more lucrative for the least ethical of black market producers. Similar situation with fentanyl when compared to previous…
Ha, funny. I thought it must be “p2p mesh” network architecture at first, then checked the comments and was like “oh p2p distributed meth?” Like you, hahaha
Re: The main thing about P2P meth is that there's so much of it (2021)
#249The ephedrine (or pseudoephedrine) synthesis is a one step using phosphorus/iodine reduction directly to methamphetamine. It’s simple and clean in that only an acid base extraction is required, and only one set of NP solvents. All these others syntheses with multiple steps up the chances of weird toxic solvents or contaminants creeping in. I think it’s a contaminant issue that’s exacerbated by the drug use. The gover…
Yes, i majored in chemistry.
Re: The main thing about P2P meth is that there's so much of it (2021)
#250Earlier quoted context omitted.
Sorry what? What does ego death have to do with healing a back injury?
Nothing and everything: https://www.frontiersin.org/journals/immunology/articles/10.... (This is a serious article by a serious researcher. There exists good work on Frontiers in… .) The 5-HT2A receptor is profoundly immunomodulatory. (Acid is arguably a more potent immunomodulator – an antiinflammatory one – than it is psychoactive.) Local inflammation is a thing in injury, "global" inflammation as well – there is s…
huh. glad I asked.