Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!
psilocybin is easy to find (even legally, in certain jurisdictions) or cultivate yourself.
MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
91–100 of 108 posts
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#92Earlier quoted context omitted.
While I agree that I'd love to have a guarantee on purity, the way to do that is just to make LSD legal, rather than have some private equity backed pharma company tie up the supply. LSD should be a case like insulin or the polio vaccine, as it offers an immense amount of potential for the planet. Sure, if they want to make money by offering retreats in clinical settings for people too afraid to spend an afternoon wi…
Except just legalization is no guarantee of safety or purity. Look at the Vitamin Industry as an example. The general public thinks that manufacturers of those bottles in the vitamin aisle are required to follow the same standards set by the FDA as those in OTC pain relief in the next aisle over.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#93It is tragically funny to consider linking quietness of mind with LSD. It is everything but quiet
The "neuroplasticity" which leads to a relative quietness presumably comes after the psychedelic experience. Interestingly, the paper only lists the following adverse effects: visual perceptual changes, nausea, and headache. Given that the patients in the double-blind study were those who suffer from moderate to severe Generalized Anxiety Disorder, I could imagine some significant anxiety in the 200 µg active group!…
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#94The psilocybin data tells a similar story. One or two sessions outperforming months of conventional meds. The fact that both LSD and psilocybin work on neuroplasticity probably isn't a coincidence. Hope regulators don't drag their feet on this for another decade.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#95The psilocybin data tells a similar story. One or two sessions outperforming months of conventional meds. The fact that both LSD and psilocybin work on neuroplasticity probably isn't a coincidence. Hope regulators don't drag their feet on this for another decade.
As someone that has done mushrooms a dozen or so times, I would never ever take them when I’m anxious or depressed. That’s a sure fire way to have a horrible trip. Maybe these are referring to pretty small doses.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#96> It's usually treated with medications like Zoloft and Paxil that boost and stabilize the neurotransmitter serotonin, leading to reduced anxiety and enhanced emotional well-being How do figure the boost and stabilize part for a patient? Do they take samples of neurotransmitters in the spinal fluid before and after and looking for neurotransmitter concentrations?
There's a divide in the marketing language vs the research language on this topic. Marketing says some handwavy statement like "Zoloft stabilizes serotonin levels", but the research on the topic basically says that we assume that's how it works based on what we know about the brain & the drug, but we don't actually have proof of the mechanism.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#97Earlier quoted context omitted.
There's a divide in the marketing language vs the research language on this topic. Marketing says some handwavy statement like "Zoloft stabilizes serotonin levels", but the research on the topic basically says that we assume that's how it works based on what we know about the brain & the drug, but we don't actually have proof of the mechanism.
I always think for some reason that by now with all advancements in technology they'd eventually get to a point where they start measuring these things so going to doctor like that people might hear "your level were out of balance, here are the numbers" and then they get treatment and now, look, another lab result shows we fixed your levels. But it doesn't seems we are quite there yet.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#98Earlier quoted context omitted.
I always think for some reason that by now with all advancements in technology they'd eventually get to a point where they start measuring these things so going to doctor like that people might hear "your level were out of balance, here are the numbers" and then they get treatment and now, look, another lab result shows we fixed your levels. But it doesn't seems we are quite there yet.
You can't exactly pull some brain matter out to send to the lab, which makes research very difficult.
I was mostly thinking maybe sample the blood or spinal fluid, or use imaging tracing markers to see how the imbalance manifests and then it can be corrected.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#99Earlier quoted context omitted.
Yeah, of course that's all legit concerns and demands. However, I dislike the notion this "dangerous street drug" was graciously made to somethings "useful" and safe by the pharma industry. It's the same its always been. Especially around the time of its prohibition. I am calling out a pattern. It's a bit similar to pharma going into the jungle, taking some natural compound (possibly known to an indigenous tribe), mo…
Sandoz was the first to manufacture LSD under the product name Delysid.
Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)
#100Earlier quoted context omitted.
mhm where i live you can go to a hydro grow store and buy the spores that you definitely SHOULD NOT inject into the aio grow bag conveniently placed nearby lol
Some will sell an already conolized growbox. Much harder to fail than the spores.