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MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

sciencedaily.com

51–60 of 108 posts

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#51

Earlier quoted context omitted.

Near as I can tell, they are essentially synonyms, but in practice "derivate" is "a product obtained chemically from a raw material", while "derivative" tends to be used in the mathematical or financial senses.

Kinda like orient and orientate. Maybe there's a word for this class of variations. Or variants?

If there isn't already, "variantate" seems appropriate to mean "inappropriately adding the suffix -ate".

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#52
post #14
post #7

It is tragically funny to consider linking quietness of mind with LSD. It is everything but quiet

The "neuroplasticity" which leads to a relative quietness presumably comes after the psychedelic experience. Interestingly, the paper only lists the following adverse effects: visual perceptual changes, nausea, and headache. Given that the patients in the double-blind study were those who suffer from moderate to severe Generalized Anxiety Disorder, I could imagine some significant anxiety in the 200 µg active group!…

You're describing what's called a critical period.

These are well established and lots of research is going on as to why psychedelics seem to put us into a critical period.

Lsd, psylocybin and mdma all seem to do it. Peyote does too.

While in the critical period, usually a week to 3 months, it is very important to surround oneself with what they want to focus on.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#53

I’d be afraid of a treatment like this where you’re sort of different after one treatment. From experience taking ssris, I took one one that worked so well that I had to stop taking it because it removed stress to the extent that I wouldn’t get to class on time or get my homework done before deadlines. Eventually I found a medicine that worked for me. But, if there’s a “before” vs “after” one shot treatment, you have…

I think curing GAD will mean changing your personality. There's always going to be a before/after you, that's the whole point. The important part is being able to reliably know what the "after you" will be so you can be sure that you want that change to happen.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#54

Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!

Nitpick: you will probably never be able to try it legally.

There are lots of ways you could try LSD tho.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#55

Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!

psilocybin is easy to find (even legally, in certain jurisdictions) or cultivate yourself.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#56

Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!

psilocybin is easy to find (even legally, in certain jurisdictions) or cultivate yourself.

mhm where i live you can go to a hydro grow store and buy the spores that you definitely SHOULD NOT inject into the aio grow bag conveniently placed nearby lol

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#57

I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans. It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them. These experiments need a control where they just take the drug and they don't have medical staff around.

Isn't that basically the same as them using a placebo? If just care has the same effect, then surely heavily monitoring them while providing a placebo drug should work.

The problem is you can very obviously tell that you have a placebo because nothing is happening. Some studies mitigate that issue by giving a microdose but then maybe only the microsose is necessary? It seems like a hard problem

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#58
post #56

Earlier quoted context omitted.

psilocybin is easy to find (even legally, in certain jurisdictions) or cultivate yourself.

mhm where i live you can go to a hydro grow store and buy the spores that you definitely SHOULD NOT inject into the aio grow bag conveniently placed nearby lol

Some will sell an already conolized growbox. Much harder to fail than the spores.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#60

I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans. It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them. These experiments need a control where they just take the drug and they don't have medical staff around.

Isn't that basically the same as them using a placebo? If just care has the same effect, then surely heavily monitoring them while providing a placebo drug should work.

But that doesn't test if the LSD helps in a non-clinical setting, only that the monitoring and attention helps
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