Earlier quoted context omitted.
As a non expert, I can't pronounce myself on the subject, I found this recent study: https://www.mdanderson.org/newsroom/research-newsroom/proton... But on the subject of discoveries and practical uses, the IBA cyclotrons are also used for other purposes than proton therapy: cleaning exotic fruits from dangerous substances and personalized medicine.
This may be one of the good cases, then. I'm not an expert in cancer but I am a biologist and physician. The head and neck cancer (here) and various pediatric indications get the most attention but it has felt that proton therapy has been seeking an indication for almost 40 years now. https://www.thelancet.com/journals/lancet/article/PIIS0140-6... The study was designed to show non-inferiority, which doesn't preclude…
From my visits, they mostly focus on children that have some very nasty cancers, the IBA hospitals are all designed with children in mind (to avoid stressing them), and from my memory, a unique hospital is often enough to treat a whole country for the kind of cancer they target.
Now, if it is on par with classical radiotherapy BUT it gives less subsequent problems, it might be worth the cost as subsequent problems can be as expensive or even more than the original treatment. It becomes an actuarial issue to know where is the tradeoff.