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Ultrasound Cancer Treatment: Sound Waves Fight Tumors

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Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#21

Post by candiddevmike »

CGMthrowaway wrote: post #10

What are the chances that breaking up a tumor this way seeds cancer elsewhere in the body? 2024 meta analysis of seeding I didn't see ultrasound in there: https://pubmed.ncbi.nlm.nih.gov/39605885/ Here is a study on AEs specifically from this type of ultrasound: https://journals.plos.org/plosone/article?id=10.1371/journal... Quote: "Cavitation detaches cancer cells/emboli from the primary site and thereby releases th…

> The mechanical destruction of tumors likely leaves behind recognizable traces of cancer proteins that help the immune system learn to identify and destroy similar cells elsewhere in the body, explains Wood

Seems a little too speculatively worded, IMO.

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#22

Post by pedalpete »

CGMthrowaway wrote: post #10

What are the chances that breaking up a tumor this way seeds cancer elsewhere in the body? 2024 meta analysis of seeding I didn't see ultrasound in there: https://pubmed.ncbi.nlm.nih.gov/39605885/ Here is a study on AEs specifically from this type of ultrasound: https://journals.plos.org/plosone/article?id=10.1371/journal... Quote: "Cavitation detaches cancer cells/emboli from the primary site and thereby releases th…

It seems they are initially focused on pancreatic cancer, which has a very low survival rate ~14% [1].

In theory, this may mean that metastisizing this tumour could destroy it in the pancreas, but allow the cells to spread to more treatable locations?

1 - https://www.canceraustralia.gov.au/cancer-types/pancreatic-c...

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#23

Post by agumonkey »

CGMthrowaway wrote: post #15
agumonkey wrote: post #12

Earlier quoted context omitted.

It would not be the first therapy that may promote spread while curing the primary site. Hopefully there are measures to assess the cost / benefits.

For sure. Goes without saying in any cancer treatment that cost/benefit is a prime consideration. Still, that will not stop me from asking the question. You can't do that analysis without the answers after all.

Stopping you wasn't my intent. I'm just a visitor sharing some stuff.

If any medical professional could give answers that would be neat.

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#24

Post by adamredwoods »

CGMthrowaway wrote: post #10

What are the chances that breaking up a tumor this way seeds cancer elsewhere in the body? 2024 meta analysis of seeding I didn't see ultrasound in there: https://pubmed.ncbi.nlm.nih.gov/39605885/ Here is a study on AEs specifically from this type of ultrasound: https://journals.plos.org/plosone/article?id=10.1371/journal... Quote: "Cavitation detaches cancer cells/emboli from the primary site and thereby releases th…

Chemo post-histrophy would remove any lingering cancer cells effectively. Cancer cells need lots of fuel or they stop replicating, and this is what traditional chemo is great at stopping.

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#25

Post by TaupeRanger »

CGMthrowaway wrote: post #10

What are the chances that breaking up a tumor this way seeds cancer elsewhere in the body? 2024 meta analysis of seeding I didn't see ultrasound in there: https://pubmed.ncbi.nlm.nih.gov/39605885/ Here is a study on AEs specifically from this type of ultrasound: https://journals.plos.org/plosone/article?id=10.1371/journal... Quote: "Cavitation detaches cancer cells/emboli from the primary site and thereby releases th…

We simply won’t know until they do the inevitable phase2/3 RCTs. They will need to show that this method helps people survive longer or with better quality of life than the current standard of care.

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#26

Post by jjtheblunt »

darkerside wrote: post #2

Dumb question, but isn't there a risk of spreading cancer causing proteins throughout the body with this approach?

the article talks about this, the (too vaguely explained) tldr is that pulverization allows neoantigens to be exposed to the immune system rather than hidden within a tumor. i saw elsewhere (weeks ago) an article that this worked excellently, but this article seems to not reference it.

this is one such article:

https://viterbischool.usc.edu/news/2025/11/tricking-tumors-i...

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#27

Post by moralestapia »

jtbaker wrote: post #14
moralestapia wrote: post #9

Earlier quoted context omitted.

Hey, I'm curious, did you have symptoms or did you just find it by chance?

no symptoms. first identified the lesion a few years back and it hadn't changed over a few subsequent appointments. exam this year, it had grown a small amount 5mmx5mm to 6mmx8mm - still considered small, but the change was enough for the Drs to recommend treatment. I have been treated by Dr. Dan Gombos[1] at MD Anderson and received excellent care. [1] https://faculty.mdanderson.org/profiles/dan_gombos.html

Interesting, thanks.

Best wishes!

Re: Ultrasound Cancer Treatment: Sound Waves Fight Tumors

#30

Post by flir »

candiddevmike wrote: post #21
CGMthrowaway wrote: post #10

What are the chances that breaking up a tumor this way seeds cancer elsewhere in the body? 2024 meta analysis of seeding I didn't see ultrasound in there: https://pubmed.ncbi.nlm.nih.gov/39605885/ Here is a study on AEs specifically from this type of ultrasound: https://journals.plos.org/plosone/article?id=10.1371/journal... Quote: "Cavitation detaches cancer cells/emboli from the primary site and thereby releases th…

> The mechanical destruction of tumors likely leaves behind recognizable traces of cancer proteins that help the immune system learn to identify and destroy similar cells elsewhere in the body, explains Wood Seems a little too speculatively worded, IMO.

If it was true, couldn't you get the same effect by taking a biopsy, fragmenting the cells, and injecting them back in? Like a vaccination, in fact. Somebody must have studied that approach already.
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