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Weight loss jabs: What happens when you stop taking them

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21–30 of 125 posts

Re: Weight loss jabs: What happens when you stop taking them

#22

> "The environment that people live in needs to be one that promotes health, not weight gain. […] Obesity is not a GLP-1 deficiency," he says. This is my biggest issue with weight healthcare, the idea that if only the patient would eat correctly they wouldn’t be overweight. It’s not some moral failing a person often over eats, it very well could be some physiological issue that should be treated. It would be like tel…

That's what GLP-1 drugs are doing? Like...this is the premier argument as to why they work.

Re: Weight loss jabs: What happens when you stop taking them

#23
post #3

Earlier quoted context omitted.

What's striking here is that this is roughly the same outcome as essentially every other diet (with the intent of losing weight) out there. It's just more expensive. And possibly more hyped.

It's not hyped. It's the most effective way I've seen the people around me lose weight. Some of them have lost a tremendous amount of weight very quickly. But a know a couple of them that went off it and the weight came back pretty quickly. It really is just a suppression of hunger, nothing more than that.

It can be hyped because jabs bring immediate results. And it can be prescribed by almost every doctor so number of people who can report is big, and therefore visible results can be further disseminated (hyped).

But… treatment is working.

Question is at what cost.

If something is too good to be true, one has to ask what is behind it. But perhaps it is a similar situation to when antibiotics were invented.

Re: Weight loss jabs: What happens when you stop taking them

#24
post #19

Being overweight is a chronic disease. Just like alcoholism, or any kind of other addictions. I've struggled with alcohol abuse, and once you come to the realization that you're abusing it, the fix FOR ME was relatively simple: I stopped (under medical supervision) drinking, or to be more precise: I stopped starting to drink. I have no problems not drinking, I have a problem that when I start I cannot stop. I have th…

It's frustrating. "Just Eat Less" is roughly the way to lose weight, but the problem is not that fat people are so unbelievably stupid that they didn't know this. I am sure for some people it really is that simple. Not us. My weight has been a bit of a rollercoaster. I've never been terribly thin, but I've been "not technically obese" from time to time. I'm currently back on the downswing, but God, what a pain in the…

> the problem is not that fat people are so unbelievably stupid that they didn't know this

I don't suggest this applies to you, but even a small amount of searching around and reading stuff on the web will reveal a substantial subgroup of outright thermodynamics deniers.

Re: Weight loss jabs: What happens when you stop taking them

#25

> "The environment that people live in needs to be one that promotes health, not weight gain. […] Obesity is not a GLP-1 deficiency," he says. This is my biggest issue with weight healthcare, the idea that if only the patient would eat correctly they wouldn’t be overweight. It’s not some moral failing a person often over eats, it very well could be some physiological issue that should be treated. It would be like tel…

I don't have a horse in this race, but from my personal experience eating satiating whole foods with lower glycemic index, higher fiber and protein content makes it very difficult to gain excessive weight.

On the asthma front, from experiences with someone close to me -- getting in great physical shape (with caveats regarding training) DID indeed help greatly with broncho-constriction and higher scores on FEV. Basically symptoms and inhaler use went down tremendously over a few years and a physical transformation.

Re: Weight loss jabs: What happens when you stop taking them

#26
post #3

Earlier quoted context omitted.

What's striking here is that this is roughly the same outcome as essentially every other diet (with the intent of losing weight) out there. It's just more expensive. And possibly more hyped.

It's not hyped. It's the most effective way I've seen the people around me lose weight. Some of them have lost a tremendous amount of weight very quickly. But a know a couple of them that went off it and the weight came back pretty quickly. It really is just a suppression of hunger, nothing more than that.

> It really is just a suppression of hunger, nothing more than that.

It is actually a lot more than that. Many people on Ozempic report better impulse control (food or otherwise). Many stop or significantly reduce alcohol intake. It seems that gut hormones are linked to reward pathways in the brain.

Re: Weight loss jabs: What happens when you stop taking them

#27
post #2

TLDR: "...evidence so far suggests that, between one and three years after stopping the medication, people will see a "significant proportion of weight" go back on...Somewhere in the region of 60 to 80% of the weight that you lost will return..."

Surprise surprise, it's not like the drug did anything to improve the patient's discipline...

Re: Weight loss jabs: What happens when you stop taking them

#28
I did lose 30-40kg about 2 years ago on Ozempic.

I don't count calories. I went off Ozempic (now Mounjaro) and I gain weight at about 0.5-1kg a month.

As I am resistance (gym) training, significant % of that ends up being muscle mass rather than fat.

So I end up taking Mounjaro for about 1-2 months every 3-4 months, approximately 33% of the time being "on".

Funnily, I end up with bulk/cut periods without doing them explicitly. This ends up working well for growing muscles.

Notice all people in the story are women. I guess pairing GLP-likes with bodybuilding works quite well for men. As times goes on, I end up needing mounjaro less due to my increased muscle mass.

Re: Weight loss jabs: What happens when you stop taking them

#29

Interesting link: a company called Fractyl Health is studying a surgical procedure they call "Revita," that they hope can keep weight off for patients after they discontinue GLP-1s.[0] The premise, IIUC, is that obesity is driven partly by mucosal overgrowth on the duodenum. This thicker-than-expected layer of mucus is less porous, which leads your digestive system to underestimate the number of calories you've consu…

> Revita basically re-surfaces the duodenum.

Does this reduce mucous production going forward? Otherwise, it seems like it would be a temporary effect.

Re: Weight loss jabs: What happens when you stop taking them

#30

Being overweight is a chronic disease. Just like alcoholism, or any kind of other addictions. I've struggled with alcohol abuse, and once you come to the realization that you're abusing it, the fix FOR ME was relatively simple: I stopped (under medical supervision) drinking, or to be more precise: I stopped starting to drink. I have no problems not drinking, I have a problem that when I start I cannot stop. I have th…

since I also share the ability to cold turkey on most anything, what you can completly stop eating is processed food, or anything that requires an advanced chemical engineering degree to decipher, ditch most of the carbs, ALL of the sugar. Meat, veggies,fruit,grains,nuts,the most complex packaged foods I buy are yogurt, and bread from an outfit that contracts farmers to grow wheat, pickles, stuff from wierd and wonderfull ethnic groceries where they openly miss there country and insist on having you try the good stuff!, wild food, tucked away farm markets, but most of all, I put my body in charge, which requires listening, but once you realy clean up, perhaps you will find as I have, that certain off the record indulgences have very significant negative phisiological repercusions, on a one to one basis. but this practice is not for dilly dalyiers, so
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