51–60 of 120 posts
As a kid I had nearly daily migraines - go into a very dark quiet room and be happy when I fell asleep, since I knew the migraine wouldn't be there when I woke up.
These days it's just headaches, 99% sure it's muscle tension in my neck. Kinda doubt GLP-1 could do anything for that, but I'd be pleasantly surprised....
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Nobody understands why it all helps, they just noticed it does work for something, quickly pushed it to the market first to get patents and get all the profits from it before generics + derivatives hit their pockets. Now, everyone is studying it because there's all new funding coming in for it and finding other versions of it that they can profit off it. Nobody knows what migraine really is, so this isn't a surprise…
> Keep in mind that a lot of the benefits go away once patients come off GLP-1 All medicines taken for chronic conditions as this way.
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I had just assumed that all these new things this is a cure for are just down stream affects of being overweight, and losing the weight also reduces the incidence of these other issues as well.
One reported benefit from Ozempic is that it improves self control. For instance, there are some studies that show it's easier to stop smoking on Ozempic[1]. I can't think of any way that would be modulated just by being less overweight. [1]: https://www.goodrx.com/classes/glp-1-agonists/semaglutide-fo...
Source: currently using GLP and seeing reduced positive feedback from alcohol (incidentally)...
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
It’s miracle drug, I’ve been on it for a few years now, it would have been sooner but usage data wasn’t available at the scale I needed before the ozempic craze. I have hEDS and part of that is ME/CFS and uncontrollable weight gain, so naturally I was looking for help with weight loss with the understanding that drugs that help with weight loss could be treating an underlying mechanisms that was causing the weight ga…
(Also have hEDS.)
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There is large-enough consensus on this drug for its main use cases (treating diabetes and obesity), but more importantly for this conversation: it's actually quite common for drugs to get new indications after their initial one --- at which point, there might be a new, broader consensus on what the drug is good for. Clinical trials are designed to treat a very specific subclass of individuals; pharmaceutical compani…
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It’s miracle drug, I’ve been on it for a few years now, it would have been sooner but usage data wasn’t available at the scale I needed before the ozempic craze. I have hEDS and part of that is ME/CFS and uncontrollable weight gain, so naturally I was looking for help with weight loss with the understanding that drugs that help with weight loss could be treating an underlying mechanisms that was causing the weight ga…
GLP-1s seem to induce/mimic gastroparesis, which also can occur with hEDS. Has that been an issue? Also, do you have MCAS? (Also have hEDS.)
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
No research out on, say, alcoholism yet, but I'd hazard a guess the results are the same.
This is not a cravings loss drug but largely a cravings management drug. Which is still pretty great but it saddles healthcare funding systems with an enormous burden for the next 20 years. Or you keep it private, which means you introduce an enormous gulf of health inequality.
I hate that our solution to obesity is not the way Iceland treated it's youth drinking problem: reduce access to the harmful thing, give people money and support to do the healthy thing. Stick with it instead of cancelling the program if it doesn't show results in 4 years.
Modern food (started in the 80s) has carefully been engineered to be as addictive as possible, health consequences be damned. Let's start fixing the problem there.
Obesity is associated with increased rate of migraine, so their symptoms could have gone away by virtue of losing weight. Let's see what it does for non obese.
Oh man, I'd love for a reduction in that. I sort-of deal with it. As a kid I had nearly daily migraines - go into a very dark quiet room and be happy when I fell asleep, since I knew the migraine wouldn't be there when I woke up. These days it's just headaches, 99% sure it's muscle tension in my neck. Kinda doubt GLP-1 could do anything for that, but I'd be pleasantly surprised....