31–40 of 120 posts
Earlier quoted context omitted.
There is large-enough consensus on this drug for its main use cases (treating diabetes and obesity), but more importantly for this conversation: it's actually quite common for drugs to get new indications after their initial one --- at which point, there might be a new, broader consensus on what the drug is good for. Clinical trials are designed to treat a very specific subclass of individuals; pharmaceutical compani…
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Earlier quoted context omitted.
There is large-enough consensus on this drug for its main use cases (treating diabetes and obesity), but more importantly for this conversation: it's actually quite common for drugs to get new indications after their initial one --- at which point, there might be a new, broader consensus on what the drug is good for. Clinical trials are designed to treat a very specific subclass of individuals; pharmaceutical compani…
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Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
I had just assumed that all these new things this is a cure for are just down stream affects of being overweight, and losing the weight also reduces the incidence of these other issues as well.
[1]: https://www.goodrx.com/classes/glp-1-agonists/semaglutide-fo...
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
I had just assumed that all these new things this is a cure for are just down stream affects of being overweight, and losing the weight also reduces the incidence of these other issues as well.
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
All I know is I had some miserable side effects that started after a couple years that just progressively got worse while on them... when I found out it was the Trulicity/Ozempic I stopped, and the effects coming off were nearly as miserable... took almost a year to recover coming off and still dealing with the fallout.
Is there any good consensus on what the deal is with this drug yet? I don't know how to think about GLP-1. In the headlines it seems like every month it's a miracle cure for something new, yet we don't really understand it? But it seems like just generally...everyone, including me, would benefit from being on it...? The whole thing makes me uneasy but I'm not exactly sure why outside of it seems weird to have one dru…
It seems weird because we hate finding “bugs” in our bodies, but it happens all the time. Another example: low dose metformin is largely considered beneficial for most people, at least in a small way. But very few people who aren’t diabetic take it, as the drawback of possible side effects outweighs the potential benefit for someone who doesn’t have symptoms in the first place. Same thing here. Would it benefit you?…
Earlier quoted context omitted.
It seems weird because we hate finding “bugs” in our bodies, but it happens all the time. Another example: low dose metformin is largely considered beneficial for most people, at least in a small way. But very few people who aren’t diabetic take it, as the drawback of possible side effects outweighs the potential benefit for someone who doesn’t have symptoms in the first place. Same thing here. Would it benefit you?…
Metformin's side effects are pretty minor, I find. So don't let that possibility stop you if you think you could benefit.
If you’re obese, have metabolic syndrome, have T2D, or any other number of issues that we’ve seen GLP-1s (or metformin) help with - then the medications can be a godsend.
Earlier quoted context omitted.
I had just assumed that all these new things this is a cure for are just down stream affects of being overweight, and losing the weight also reduces the incidence of these other issues as well.
One reported benefit from Ozempic is that it improves self control. For instance, there are some studies that show it's easier to stop smoking on Ozempic[1]. I can't think of any way that would be modulated just by being less overweight. [1]: https://www.goodrx.com/classes/glp-1-agonists/semaglutide-fo...
Makes sense