Wasn't his partner Crick high on LSD when he discovered the double-helix structure of DNA?
The closest thing is Franklin's Photograph 51 which took about 100 hours to compile and then took another year to do all the calculations to confirm the position of each atom.
Watson and Crick (without the consent of Franklin) saw this Photograph, did some quick analysis, and came up with a couple of models that could match Franklin's photograph. Watson and Crick were already at work trying to crack the model of DNA, but once they got access to Franklin's work, it became the entire basis of their modeling. After about 2 months of this they finally found the double helix structure that matched Franklin's findings.
I doubt Crick was on LSD for an entire 2 months. Perhaps he was tripping when he first viewed the photograph?