Earlier quoted context omitted.
You are reaping the benefits of having an active fitness regime in your 30s . The average 50 year old who starts exercising today will never get to your fitness level .
I don’t think I’m convinced of that. Most fitness measures saturate as you approach a limit. For example, you can build muscle mass rapidly in the first couple of years but it slows dramatically as you approach your genetic limit. It only takes a few years of consistent training to get to that asymptotic level. So on that measure, you can basically “catch up” to your hypothetical “always trained” self. While you migh…
Ageing accelerates around age 50 ― some organs faster than others
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Re: Ageing accelerates around age 50 ― some organs faster than others
#112There was another recent study that made the front page of HN (would have to search to find it) that found two "peaks" of aging, at 44 and 60. As someone in my late 40s, I certainly identified with that. I was in fairly good shape and feel like, despite some grays and some crows feet, my body was relatively the same from my early 20s to my early 40s. 44 really did hit me like a ton of bricks though - working out got…
I'm 30. I feel 70. No clue why. I take vitamin supplements, I exercise, I try to sleep, I had basic blood test. Nothing.
Well stop using body cavities as a reactor would be a good first step. :p
More seriously could be signs of depression. I felt way worse when I was depressed. Also could be something like chronic fatigue syndrome too.
P.S. get your vitamin-d levels checked. It’s a super common deficiency.
Re: Ageing accelerates around age 50 ― some organs faster than others
#113Re: Ageing accelerates around age 50 ― some organs faster than others
#114Earlier quoted context omitted.
I’ve been athletic most of my life. At 42 I feel much older than at 32. Chronic injuries add up! Be careful out there everybody
Have you happened upon Keith Barr’s work on tendon repair? Up to a few years ago tendon injuries were thought to be mostly unfixable (you could strengthen what was left of an injured tendon at best) but Barr’s work is proving otherwise. And using a very low risk isometric exercise protocol. It won’t make you feel 32 again but it might help you get rid of a lot of lingering aches and pains.
That's Keith Baar; I looked it up.
Keith Barr focused on musical technology at MXR, Alesis and eventually Spin Semiconductor. His legacy is MXR pedal effects like the Phase-90, the MidiVerb digital reverb series and the Spin FV-1 digital reverb chip.
Re: Ageing accelerates around age 50 ― some organs faster than others
#115Earlier quoted context omitted.
I think this argument only makes sense on the surface level. If it was the case that humans hit some hard limit to growth (perhaps running out of 'room' to grow, or losing the ability to process new energy, etc), then I think it could make sense to do this sort of 'graceful decommissioning' behavior, which we'd come to know as aging. But is there a hard limit we hit, aside from the aging process itself? None is obvio…
It's commonly thought that if your cells kept dividing the way that they do when you're young and they accumulated genetic damages you'd get cancer more often.
That isn't a satisfying answer because humans can obviously generate germline cells that don't suffer from this issue.
So the question becomes why can't somatic cells repair themselves to be as healthy as germline cells?
Re: Ageing accelerates around age 50 ― some organs faster than others
#116I've only opened these comments in the hope somebody here will debunk these findings or at least point out they are dubious... :(
Agree - I’m 58 and still do the same workout I did in my 30s and 40s including 3 sets of 15 to 20 pull-ups depending on the day. I also still skate (hockey) 2 -3 times a week with a bunch of retired pros (echl, nhl, etc) and typically put up a bunch of points every skate (possibly slightly more assists now but I attribute that more toward enjoying that more these days and not needing to be so flashy)
Are you still taking rapamycin and if so what are your observations from taking it for the past few years?
Re: Ageing accelerates around age 50 ― some organs faster than others
#117Earlier quoted context omitted.
I'm 30. I feel 70. No clue why. I take vitamin supplements, I exercise, I try to sleep, I had basic blood test. Nothing.
How's your diet? Do you get plenty of vegetables? Cruciferous especially. Do you avoid fried foods? Alcohol? Caffeine? Sugar? Consuming enough high quality protein? How's your sleep? Do you avoid eating within a couple hours of bedtime? Are you waking up to pee in the night?
I used to eat a salad every day until recently when I decided I can't be bothered to visit work canteen anymore. They gave shit food but I'd always take an extra big salad of raw vegetables. Recently my diet got worse. I used to love cooking, but now I can't be bothered, so it's instant ramen, milk with buckwheat, or potatoes + egg + bacon + fried vegetables. Not sure what "high-quality protein" is.
I had a period when I'd drink a litre of vodka every weekend, but now it's like "one beer to chill after work". Weed is my vice though, I'm stoned every weekend. I try to cut though because the amounts I used to consume now make me tired, so I'm aiming for smaller doses.
I try to eliminate caffeine, but I keep learning about new sources of it. It's literally today that I learned just how much caffeine cola has.
Sugar is my vice definitely. I cycle every day, so I burn it. When I don't cycle I hit the gym.
Sleep... it happens often that I schedule time to sleep, I put away my phone, but then I just don't fall asleep, I just lie there awkwardly in bed. Or I wake up and then can't go back to sleep. I feel like the quality of my sleep isn't there really, which is why I decided to cut caffeine in the first place. But then I sometimes have a streak where I can sleep and function well. One thing is that I tend to get sleepy in the afternoon. If I go to bed and manage to get one full cycle of sleep, I won't feel completely miserable. I don't have big meals before bedtime but often I keep snacking on something.
Whether I wake up to pee depends on how much liquid I drink before. I'd say 50/50.
Re: Ageing accelerates around age 50 ― some organs faster than others
#118Earlier quoted context omitted.
I'm 30. I feel 70. No clue why. I take vitamin supplements, I exercise, I try to sleep, I had basic blood test. Nothing.
Well stop using body cavities as a reactor would be a good first step. :p More seriously could be signs of depression. I felt way worse when I was depressed. Also could be something like chronic fatigue syndrome too. P.S. get your vitamin-d levels checked. It’s a super common deficiency.
When I think of the joy that I experienced from my body cavity and what "nothing" I feel now... gah. It's like a light gone.
I think I've always been low-key depressed but there was always this ray of hope. But now it's dawning upon me "this is it, that's life, take it or leave it" and that's just terrifying and demotivating. I feel like I have to accept that things I wanted so bad just won't happen. And with each passing day my exhaustion keeps getting worse so I feel like the number of things that bring me joy keeps getting smaller.
Re: Ageing accelerates around age 50 ― some organs faster than others
#119Earlier quoted context omitted.
Perhaps not a phase-out program, but a progressive shut-down program, as a trade off between peak performance and total lifespan, where the characteristic patterns of ageing is what allowed humans to live much longer than other animals around the same size. Similar to the idea in this comic: https://www.badspacecomics.com/post/the-suit By this logic, as a hedge against sudden death around ~50, the human body start cr…
I think this argument only makes sense on the surface level. If it was the case that humans hit some hard limit to growth (perhaps running out of 'room' to grow, or losing the ability to process new energy, etc), then I think it could make sense to do this sort of 'graceful decommissioning' behavior, which we'd come to know as aging. But is there a hard limit we hit, aside from the aging process itself? None is obvio…
telomeres
Re: Ageing accelerates around age 50 ― some organs faster than others
#120Earlier quoted context omitted.
Agree - I’m 58 and still do the same workout I did in my 30s and 40s including 3 sets of 15 to 20 pull-ups depending on the day. I also still skate (hockey) 2 -3 times a week with a bunch of retired pros (echl, nhl, etc) and typically put up a bunch of points every skate (possibly slightly more assists now but I attribute that more toward enjoying that more these days and not needing to be so flashy)
>"3 sets of 15 to 20 pull-ups depending on the day" It is always 20 for me. 4 sets. I am 64. I used to do 30 when I was a teen but I was much lighter then. also lots of swimming, cycling, hiking canoeing etc. etc
That’s awesome. I’m 60 and find pull ups are getting harder. I’d be delighted to get 20 in a set.