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Bill Atkinson's psychedelic user interface

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Re: Bill Atkinson's psychedelic user interface

#111

Post by gavinray »

gehwartzen wrote: post #48
gavinray wrote: post #27

Earlier quoted context omitted.

I've done it a few times. Unlike DMT, you don't have to vaporize it. It's active intranasally and well as buccally/sublingually. Effects-wise, it feels roughly identical to DMT but with a longer duration.

To me it feels like a completely different drug compared to nnDMT. 5-meo-DMT also feels very different depending on the roa from my experience (vaped vs IM)

Ah, a fellow "I've IM'ed tryptamines" person.

I made this mistake exactly once, with 4-AcO-DMT.

That was the last time I ever did such a thing.

Re: Bill Atkinson's psychedelic user interface

#112

Post by colecut »

t-3 wrote: post #43
demiters wrote: post #3

Not a big fan of the ongoing productisation of transcendental, possibly brain-scrambling experiences. Keeping them somewhat less accessible tends to filter out people who don't do their homework to understand the substance and who consider it just another novel experience to try on a whim, which increases the risk of negative outcomes.

I disagree. Every time I've seen someone get a "bad trip", they're people who read a lot and worked themselves into a state of anxiety over the fact that something could go wrong. If they had just approached it like "ooh lets get high and have fun" rather than "I have to do X, Y, Z or else it's going to be horrible!", they would have probably been OK. Hallucinogens have way too much gatekeeping and mysticalization ar…

I know two people who had prolonged psychotic episodes, as in, for weeks they were in their own world. These were both people who had many fun/enjoyable experiences beforehand.

I myself have had bad / hell like experiences a small percentage of the time, despite literal hundreds of good experiences prior.

Becoming a father many years ago significantly altered my trip experience.

Dosage also plays a strong role..

These things are generally less toxic than alcohol and it is criminal to punish someone for having them or using them.. But they are also extremely powerful, and despite potential amazing experiences, do carry risks.

And they are definitely not for everyone.

Re: Bill Atkinson's psychedelic user interface

#113

Post by nick__m »

hnthrowaway0315 wrote: post #76

I'm skeptic about psychedelic. Is there enough unbiased research about these stuffs? I myself is interested in it too but so far it is in general illegal in Canada, and I don't consider myself knowledgeable enough to try it out.

there are plenty of psychedelics legal in Canada, I know of a few chemical suppliers that specialize in this. It's been at least a decade since I last ordered from them, but they are still in bussines.

However you said that your not knowledgeable and I guess that you doesn't have access to a milligrams scale, so your better to stay away and learn the theory first. A lot of psilocybin analog (alpha-MethylTryptamine was one of my favorite and it's still available) from Thikal are still legal in Canada so that book is a good place to start learning.

Re: Bill Atkinson's psychedelic user interface

#114

Post by aeon_ai »

gregschlom wrote: post #107
pdabbadabba wrote: post #92

Earlier quoted context omitted.

Could you explain what you mean by that? Who are the proponents of “big reality”? How do they fight against its disruption?

It's a joke. People often have conspiracy theories about Big Pharma trying to prevent access to novel drugs that could disrupt their cash cows. The parent was jokingly talking about "Big Reality" as an imaginary group of people who hate to see "reality" disrupted by psychedelic experiences.

When someone has a profound psychedelic experience that shows them the arbitrary nature of many social constructs, or reveals possibilities for consciousness that mainstream science doesn't acknowledge... that's genuinely disruptive to systems built on those constructs.

The resistance is real, systematic, and rational (from the perspective of maintaining current power arrangements). Not a joke.

Re: Bill Atkinson's psychedelic user interface

#115

Post by dkarl »

demiters wrote: post #3

Not a big fan of the ongoing productisation of transcendental, possibly brain-scrambling experiences. Keeping them somewhat less accessible tends to filter out people who don't do their homework to understand the substance and who consider it just another novel experience to try on a whim, which increases the risk of negative outcomes.

> Keeping them somewhat less accessible tends to filter out people who don't do their homework

I strongly disagree. Your circles might be different, but in my experience, wanting to do your homework makes it less accessible, because it tends to put you at odds with the people who are otherwise eager to grant you access. They want people with a certain mindset and an up-front faith in the process. They want people who aren't careful about ingesting psychoactive substances, are eager to put their mental health in the hands of some guy they barely know, and are going to blame their own baggage or spiritual shortcomings if it doesn't go well.

These drugs, and many others, are already pretty accessible if you are willing to take that heedless approach.

In contrast, the approach described in the article is expressly tailored for people who want to be careful and do their homework. It's for people who have access to the drug and implicitly already have access to cruder ways of using it, but who want to put in extra effort for a more controlled experience.

Re: Bill Atkinson's psychedelic user interface

#116

Post by nick__m »

nonelog wrote: post #65
ashalhashim wrote: post #50

Earlier quoted context omitted.

I assume this comment is trolling. But to be clear to readers, the link states psilocybin 50% increase in lifespan of human skin etc. not human lifespan.

"[...] extended the cellular lifespan of human skin and lung cells by more than 50%" If we assume that the effect is the same for all types of cells, it follows that the life is extended by 50% (when keeping "all other factors" constant, as usual).

It has to also down-regulate cells divisions, else it could be quite problematic.

Re: Bill Atkinson's psychedelic user interface

#117

Post by aradox66 »

mock-possum wrote: post #97
wbl wrote: post #95

Earlier quoted context omitted.

Four entered the garden: Ben Azzi, Ben Zoma, Acher and Akiva. One looked and died. One looked and was harmed. One cut down all the trees. And one entered in peace and departed in peace.

Lemme guess, Ben Zoma was the peaceful one?

Nope! Rabbi Akiva, who, as the story goes, was an illiterate shepherd until he started studying in his 40s, and went on to become one of the most renowned scholars of his era. This is why some Jewish tradition teaches that for mystical study, one should wait until the age of 40

Re: Bill Atkinson's psychedelic user interface

#118

Post by dang »

justinrubek wrote: post #87
jekwoooooe wrote: post #71

Without rigorous science and licensed professionals it would be insanity to take these drugs. They can potentially PERMANENTLY traumatize your brain possibly even _literally_ ruining your entire life. I guess that risk is worth it for some people

[flagged]

Can you please express your substantive points without getting personal? I'm sure you didn't intend to cross into personal attack but this comment is a step in that direction.

https://news.ycombinator.com/newsguidelines.html

Re: Bill Atkinson's psychedelic user interface

#119

Post by nick__m »

allears wrote: post #108
hnthrowaway0315 wrote: post #78

Earlier quoted context omitted.

That's something I'm really worried about, especially when SV is pushing it. And it is difficult to prove that research is unbiased. One of the commenters of your post says "If we legalize it we can better research it". Allow me to be rude -- this is BS. If we follow this logic we should legalize pretty much everything! I think it is polite to be rude to such dangerous thoughts. Downvote me as you see fit.

But following your logic everything would be illegal! There's a whole lot we don't know about how aspirin works, for instance. Governments should not be in the business of banning things unless there's a clear and present danger. Citizens should have the autonomy to do risky things if they want to.

Aspirin mechanisms is known since the late 1970s, it's a COX inhibitor.

Acetaminophen is the one that still mysterious, there are credible theories but they don't explain everything the substance does. The latest one I know of is that one : https://www.pnas.org/doi/10.1073/pnas.2413811122

Re: Bill Atkinson's psychedelic user interface

#120

Post by [deleted] »

lostmsu wrote: post #63
dtj1123 wrote: post #49

Earlier quoted context omitted.

Does that line of reasoning extend to things like fast food and motorcycles in your eyes? Not trying to undermine your point, just genuinely curious.

I don't see why not. Maybe no need to ban altogether, but a heavy tax on both might be useful. For motorbikes maybe just exclude accidents from coverage.

[deleted]
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