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Schizophrenia is the price we pay for minds poised near the edge of a cliff

psychiatrymargins.com

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Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#131

Post by gavinray »

cjbgkagh wrote: post #24
PaulHoule wrote: post #14

Earlier quoted context omitted.

Is there some puzzling chronic condition that isn’t on this list? https://me-pedia.org/wiki/RCCX_Genetic_Module_Theory

Of course there are. I'm guessing you're insinuating two things, it's highly improbable that individuals can have this many simultaneous issues, and it's impossible for medical researchers to miss such an anomaly. The Ehlers Danlos subset is shorter but still covers a huge amount of issues ( https://ohtwist.com/about-eds/comorbidities ). Well there is a reason why doctors kept telling me I am a hypochondriac, but I d…

Do you have a list of which SNP's are related to this/are pathological?

I have an Ancestry partial genome that I've imputed to expand. Would be curious whether those SNP's are present in the data.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#132

Post by mandmandam »

talentedcoin wrote: post #82
mandmandam wrote: post #66

Earlier quoted context omitted.

> It seems that pot is about the worst thing that a schizoaffective/schizophrenic person can use. This isn't entirely true, and it's a dangerous misconception. High THC, low CBD cannabis wouldn't be recommended, but that's exactly what making cannabis illegal selects for. High CBD, low/zero THC cannabis, on the other hand, will probably be one of the paths to treatment if we ever get over our Reefer Madness and pharm…

“Dangerous misconception”? Get out of here with that. Cannabis is dangerous for schizoaffective people. Why are people that smoke pot so tiresome about this? Just accept that it’s not good for everyone!

> “Dangerous misconception”? Get out of here with that.

I will not.

The demonization of cannabis has led directly to it becoming high THC and low CBD, as I said. It also has lead to it often being tainted with all manner of adulterants, from ketamine to glass beads to plaster dust to worse.

> Cannabis is dangerous for schizoaffective people.

CBD is a leading target of research for it's anti-psychotic properties; and if you don't know this it's a complete mystery to me why you feel entitled to weigh in.

And it's not even the only compound in cannabis that is being investigated; there are others with anti-psychotic and synergistic potential.

> Why are people that smoke pot so tiresome about this?

What if what I'm saying might be true, and you're dead wrong to accuse anyone who disagrees of being a 'tiresome stoner'?

... Because, in fact, it may well be [0].

> Just accept that it’s not good for everyone!

If it's not for you, that's fine; but the wilful ignorance around cannabis over decades has caused far, far more harm than cannabis ever has.

Can you accept that it will may well have a role in treating "psychosis, in general and schizophrenia, in particular" [0]?

0 - https://pubmed.ncbi.nlm.nih.gov/22716160/

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#133

Post by mandmandam »

ChrisMarshallNY wrote: post #70
mandmandam wrote: post #66

Earlier quoted context omitted.

> It seems that pot is about the worst thing that a schizoaffective/schizophrenic person can use. This isn't entirely true, and it's a dangerous misconception. High THC, low CBD cannabis wouldn't be recommended, but that's exactly what making cannabis illegal selects for. High CBD, low/zero THC cannabis, on the other hand, will probably be one of the paths to treatment if we ever get over our Reefer Madness and pharm…

Eh, maybe. I can certainly say that I have "skin in the game." Someone very dear to me suffers from it, and it's difficult to hear theories from folks that don't have as much of a stake. That's one reason that I have compassion for parents of autistic children, that are vehemently anti-vax. I completely disagree with their stance, but I know what they are dealing with, and the very real fears and stresses that they a…

> it's difficult to hear theories from folks that don't have as much of a stake.

It's not a theory that CBD has anti-psychotic properties. It certainly does, we just don't fully understand why.

My theory is that it will someday be part of treatment plans; and as someone with skin in the game I would hope that you care enough to learn a bit more about it. The comparison to anti-vaxxers with autism in the family is not appropriate here.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#134

Post by Xmd5a »

have-a-break wrote: post #108
tony69 wrote: post #19

Earlier quoted context omitted.

In Europe this (some rec drugs bring out latent schizophrenia) is taught in med school as a “known fact” (source: psychiatrist friend) so it’s well beyond “starting to seem”

The fact that in different parts of the world the voices can be helpful instead of intrusive makes me feel like the drugs are not the problem but how external forces view the drugs or if we really wanna talk like crazy people how the drugs influence the people around you even if they do not directly know you are using the drugs.

https://news.ycombinator.com/item?id=41980986

What happens when people with acute psychosis meet the voices in their heads?

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#135

Post by adaptbrian »

woodpanel wrote: post #123
krstffr wrote: post #119

Earlier quoted context omitted.

My friend had a very similar episode with a psychosis, but turned out to be bipolar, not schizophrenic. Sounds very similar though! He was smoking a lot of weed leading up to and during the psychosis. Ended up in psychiatric ward for a month, which was followed by a couple of years of depression/introspection/therapy, but is now doing great with lithium.

It’s why I profoundly dislike the line of thinking that easier access to drugs means social progress. It’s rather a shedding off of an inconvenience for those that have no (direct) problems of functioning (eg risk of developing addiction, psychosis, etc) at the heavy costs payed by those that are more vulnerable.

I'm all for getting illicit drug users out of jail, that's social progress. There needs to be more education and attempt at shoring up mental health in the public sector and not just kicking everyone into a room and calling it a day, like the problem is solved.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#136

Post by tim333 »

suzzer99 wrote: post #9

I've lost one of my best friends to what I think is schizophrenia. We don't know because she's cut off all contact with friends and family and refuses to see a doctor. It's definitely psychosis. She thinks she's in some kind of Truman show that she calls "the game". Since none of her friends or family are willing to admit to it, then we must be in on it. We don't know her full family medical history because her dad w…

I have more friends mucked up by LSD like drugs than any other type - at any rate three of them and I don't have much in the way of junkie of alcoholic friends. I say LSD like as they all took other stuff. From my n=3 data I'd say if you do it more than once a week for more than two years you have a good chance of ending up like your friend.

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#137

Post by motorest »

overu589 wrote: post #127
have-a-break wrote: post #108

Earlier quoted context omitted.

The fact that in different parts of the world the voices can be helpful instead of intrusive makes me feel like the drugs are not the problem but how external forces view the drugs or if we really wanna talk like crazy people how the drugs influence the people around you even if they do not directly know you are using the drugs.

You’re right and wrong. The voices are quite real, we’re not alone in our own minds, and the it is the greatest taboo of society to discuss. It’s really sad, all of these sharp modernists determined upon the cult of science explanations for everything. Those who refuse to believe our thoughts are not all our own. That much mysticism is rooted in something that merely cannot be explained by the logical empirical mind.…

> It’s really sad, all of these sharp modernists determined upon the cult of science explanations for everything.

That which you try to attack and downplay as "cult of science explanations" is actually something extremely simple: you need to show something, anything at all, that actually supports your beliefs.

How can you tell something exists or works as you think it does if you are unable to show it?

Do you expect everyone should just believe anything anyone says? What is there to tell lunatics and snake oil salesmen apart from those who are actually onto something?

> Those who refuse to believe our thoughts are not all our own.

Ok, you formed an hypothesis. Now tell me, how do you go about showing others that things do work the way you think they do? How can they check them for themselves? What do you expect from others?

> That much mysticism is rooted in something that merely cannot be explained by the logical empirical mind.

If you cannot explain your beliefs, how do you expect others to just take your unverified and unsubstantiated claims as something worth considering over any random claim from any random loony?

Re: Schizophrenia is the price we pay for minds poised near the edge of a cliff

#139

Post by ChrisMarshallNY »

mandmandam wrote: post #133
ChrisMarshallNY wrote: post #70

Earlier quoted context omitted.

Eh, maybe. I can certainly say that I have "skin in the game." Someone very dear to me suffers from it, and it's difficult to hear theories from folks that don't have as much of a stake. That's one reason that I have compassion for parents of autistic children, that are vehemently anti-vax. I completely disagree with their stance, but I know what they are dealing with, and the very real fears and stresses that they a…

> it's difficult to hear theories from folks that don't have as much of a stake. It's not a theory that CBD has anti-psychotic properties. It certainly does , we just don't fully understand why . My theory is that it will someday be part of treatment plans; and as someone with skin in the game I would hope that you care enough to learn a bit more about it. The comparison to anti-vaxxers with autism in the family is n…

> is not appropriate here

Actually, if the agenda of pushing CBD therapy applies, then it is. I know a number of folks that have autistic children, of various levels, from "nerd," to "wheelchair-bound." Their parents are usually absolute saints, regardless of their political views, or misinformation diets, and live in constant pain; making daily sacrifices that I don't think many folks here, can even comprehend.

We were discussing a serious mental illness, and, as someone that is a caregiver for someone like that, I think that my experience is relevant; just as someone who believes that their child's condition was caused by something that is really a red herring.

The real villains, here, are the people that have secondary agendas (like legalizing drugs, or pushing political agendas), and look at people like us, with very real pain, as nothing but pawns, to be used to push their agenda (Think of the children!).

CBD, like Blockchain, probably has some valid application, but, because it was so unexplored, scientifically, it is currently about 75% snake-oil. We'll find out what it's good for, over time. The same can be said for other drugs, like MDMA, microdose LSD, or psilocybin.

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