201–210 of 394 posts
I wonder how this molecule will compare with gold nanoparticles [1]. Headline: Gold outperforms common weight loss drugs – and leaves muscles alone [1] https://newatlas.com/disease/obesity/gold-nanoparticles-obes...
Losing a ton of weight, especially very quickly, is extremely catabolic. Any substance that prevents this would by definition be an anabolic substance.
Since it is naturally occurring, it isn't patentable. Which means it is less likely that companies will develop a commercial product from it. Why pay to get FDA approval, if you don't get a government granted monopoly on it afterwards? This is one problem with using patents as the mechanism to incentivise development of medicine.
I've always been very, very skeptical of this claim. If there's an actual natural, identified substance with huge benefits to people, it's going to go gangbusters and you're going to make a lot, LOT of money selling it, even if you're doing it via roadside lemonade stand. It feels like this claim is usually used to promote cures and treatments with extremely low quality RCTs backing their use as a sort of panacea. I…
Since it is naturally occurring, it isn't patentable. Which means it is less likely that companies will develop a commercial product from it. Why pay to get FDA approval, if you don't get a government granted monopoly on it afterwards? This is one problem with using patents as the mechanism to incentivise development of medicine.
I've always been very, very skeptical of this claim. If there's an actual natural, identified substance with huge benefits to people, it's going to go gangbusters and you're going to make a lot, LOT of money selling it, even if you're doing it via roadside lemonade stand. It feels like this claim is usually used to promote cures and treatments with extremely low quality RCTs backing their use as a sort of panacea. I…
Delighted to discover this kind of breakthrough is based on a gnarly regular expression: https://github.com/Svensson-Lab/pro-hormone-predictor/blob/m...
> The study would not have been possible without the use of artificial intelligence to weed through dozens of proteins in a class called prohormones. I see we’re being fast and loose with the term “artificial intelligence”?
Is the muscle loss a side effect of the drug or of the weight loss?
It's nearly always a side effect of weight loss, and it's a good thing. It's confusing how people act like it's bad. If you're obese, your legs are enormously strong with crazy amounts of muscle. Have you ever seen someone obese do leg presses at the gym? They can handle tons of weight. When you lose weight, you don't need all that extra muscle . If you're carrying around 180 lbs instead of 300 lbs on your frame, all…
It's natural but that doesn't make it good. In particular, muscle loss can cause heart problems because the heart is a muscle. The body's catabolic processes don't distinguish between different kinds of muscle.
Earlier quoted context omitted.
That is absurd. Muscle mass is a huge predictor of mortality and anyone who isn't actively strength training and maintaining higher levels of muscle would see a health benefit by doing so. The idea that an overweight person has "too much muscle" is nonsense. The side affect of muscle loss from these glp-1 agonist drugs is a serious downside that everyone should be aware of and try to mitigate if they choose to take t…
There is a huge conflation of cause and effect with respect to muscle mass and longevity. Low muscle mass is associated a broad swath of illnesses, low activity, and generally poor health. Muscle mass's power as a predictor is not the same as it's utility as an intervention.
Since it is naturally occurring, it isn't patentable. Which means it is less likely that companies will develop a commercial product from it. Why pay to get FDA approval, if you don't get a government granted monopoly on it afterwards? This is one problem with using patents as the mechanism to incentivise development of medicine.
Delighted to discover this kind of breakthrough is based on a gnarly regular expression: https://github.com/Svensson-Lab/pro-hormone-predictor/blob/m...
Please, if you write regexes like these, comment them... A great way to do it is to split them up by concatenating them across a bunch of lines, and put a brief explanation at the end of each non-obvious part (to the right, on the same line). Plus that also lets you indent within nested parentheses, making it that much more understandable. I'm baffled when I come across a file like this where the code itself is heavi…
Earlier quoted context omitted.
It's nearly always a side effect of weight loss, and it's a good thing. It's confusing how people act like it's bad. If you're obese, your legs are enormously strong with crazy amounts of muscle. Have you ever seen someone obese do leg presses at the gym? They can handle tons of weight. When you lose weight, you don't need all that extra muscle . If you're carrying around 180 lbs instead of 300 lbs on your frame, all…
> Losing muscle as you lose weight is natural and good. It's natural but that doesn't make it good. In particular, muscle loss can cause heart problems because the heart is a muscle. The body's catabolic processes don't distinguish between different kinds of muscle.
Maybe this one relates more with the Americans because Ozempic became a trend there: Why are most people jumping on this drug? At least for me, besides all the cliches and stereotypes about the USA people, there's huge access to nutrition, gyms, surgical procedures, capital for buying healthy food, and medicine in general.
Americans are overweight. Our entire food chain is full of preservatives, carcinogens, and things that should not be consumed by living beings . I've spent small amounts of time in Europe, and each time literally just eating whatever junk food I wanted, I came home losing 10 or 20 pounds. The food outside of the US is just fundamentally better. Let's say you're a teenager and you want to buy yourself some soda, in Am…
Sandwich, US >:|
Sandwich, Japan :O
I don't know what to believe anymore. I think sugar isn't good for you, whether it's "real" processed sugar, or HFCS which is a fructose ratio that is the same as honey, or agave syrup which has even more fructose.
And, other countries have obesity problems too - e.g. Mexico and the UK. Are they tainted by... whatever... is the actual problem (or problems) with the US's food supply?