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Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

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Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#111

Post by droopyEyelids »

wincy wrote: post #64
lores wrote: post #50

Earlier quoted context omitted.

The drug does not directly affect muscle mass (unless you are already very lean), but heavy people are doing resistance training against their own body weight all the time, so they are strong in the absolute, even if not relatively. Weigh less and your muscles have it easier, so weaken, unless you keep them strong with exercise.

I’m not sure that’s exactly what’s happening with GLP-1 drugs. I lost 40 pounds very quickly on them and hurt my hip then my shoulder then my wrist. Felt like I was constantly getting muscle strains and random injuries. I started drinking a protein shake once a day and the random mysterious injuries stopped.

What you described doesn’t seem to be in conflict with what he described

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#112

Post by MrMcCall »

borgdefenser wrote: post #42
aitchnyu wrote: post #24

Is the muscle loss a side effect of the drug or of the weight loss?

Lean mass is just non-fat mass. That includes much more than just muscle. I can't find any evidence that GLP-1 are catabolic to muscle mass. There is no evidence I can find that GLP-1s do anything above what calorie restriction does. There is a linear relationship between calorie restriction and fat loss down to under 10% body fat. There is so much wrong information on calorie restriction from studies done on people…

YOU ARE ABSOLUTELY CORRECT. READ ^THIS^, FRIENDS.

In the end, it really is just metabolic math. As a former wrestler who did some insane weight-losing in my youth, the muscle mass loss is due to extreme calorie restriction. Besides, just sitting around starving is not a good way to become healthier in the long run, and that's where the muscle loss will be worst. To be a true journey towards better health, dieting should be accompied by at least a lot of walking and some light weight training, in the minimum.

And don't forget your supplements, kids (addressing general readership), because our foods are less nutrient dense in 2025, so find out if some supplements help energy levels on the downslope. Me and my teenagers have taken a sip / mini-gulp of a product called 'Orgain' daily for a month or so, and I have found my energy better, while having less cravings. An entire little 11oz single-size drink is way too much for me (too many vitamins, makes me sleepy), having 'just a little bit' is not at all scientific, but we seem to be thriving on that little bit of supplementation.

And, as always, avoid those processed sugars, kids! Whole sugar cane is very, very good for us, but only in moderate doses. Processed sugar is the crack cocaine of sugar cane, as opposed to just chewing a leaf of the coca plant.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#113

Post by tclancy »

dleeftink wrote: post #76
janfoeh wrote: post #41

Earlier quoted context omitted.

Heh, I just fed autoregex a regex from one of my projects, and it simply times out. It comforts me to know that billion dollar LLMs have to chew on those just as much as I do.

A proper litmus test, what's causing the hang in your case? Regex to me, is pattern finding and abstraction taken to the extreme. I like the challenge

I think what's causing the hang is using the site. I gave it [a-f0-9]{8}(?:-[a-f0-9]{4}){3}-[a-f0-9]{12} and it sat thinking about things for a few minutes. So I tried the reverse and asked it "Match a UUID" and it sat and thought about things.

Now I am enlightened.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#114

Post by nkrisc »

n4r9 wrote: post #47
loloquwowndueo wrote: post #32

Earlier quoted context omitted.

Some elements don’t occur naturally and need to be formed artificially / by force by smashing together atoms that would never smash together in nature (in some cases because those atoms in turn also don’t exist in nature).

I suspect chasd00 is making a pedantic point that the atoms are smashing together in nature. Because nature is just everything that happens. Although pedantic, it does challenge what we really mean when we say "natural". Just like what we mean when we say "chemicals". Everything is chemicals.

> Everything is chemicals.

No, not everything. Atoms, subatomic particles, light, electromagnetism, etc. are not chemicals. There are many things we experience in everyday life that are not chemicals.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#115

Post by derektank »

braza wrote: post #94

Maybe this one relates more with the Americans because Ozempic became a trend there: Why are most people jumping on this drug? At least for me, besides all the cliches and stereotypes about the USA people, there's huge access to nutrition, gyms, surgical procedures, capital for buying healthy food, and medicine in general.

Exercise is great for your health, but it generally has a negligible effect on weight loss because exercise doesn't actually consume that many calories. The biggest benefit of exercise on weight loss is the temporary exercise-induced anorexia that occurs in very high intensity workouts.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#116

Post by crazygringo »

aitchnyu wrote: post #24

Is the muscle loss a side effect of the drug or of the weight loss?

It's nearly always a side effect of weight loss, and it's a good thing. It's confusing how people act like it's bad.

If you're obese, your legs are enormously strong with crazy amounts of muscle. Have you ever seen someone obese do leg presses at the gym? They can handle tons of weight.

When you lose weight, you don't need all that extra muscle. If you're carrying around 180 lbs instead of 300 lbs on your frame, all that extra muscle goes away because there's no point in keeping it. This is a good thing.

Even if you go from 200 lbs to 180 lbs, there's a level of muscle you don't need anymore.

Losing muscle as you lose weight is natural and good. Now, obviously you don't want to lose so much that you become weak for your size, but that won't happen if you continue to be physically active. Your body is exceptionally good at maintaining the exact right level of muscle to meet the regular stresses it undergoes. (Provided you are eating enough protein, but that's easy.)

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#117

Post by toast0 »

n4r9 wrote: post #47
loloquwowndueo wrote: post #32

Earlier quoted context omitted.

Some elements don’t occur naturally and need to be formed artificially / by force by smashing together atoms that would never smash together in nature (in some cases because those atoms in turn also don’t exist in nature).

I suspect chasd00 is making a pedantic point that the atoms are smashing together in nature. Because nature is just everything that happens. Although pedantic, it does challenge what we really mean when we say "natural". Just like what we mean when we say "chemicals". Everything is chemicals.

> Everything is chemicals.

Free electrons and neutrons aren't chemicals. Free protons are Hydrogen ions though.

With the exception of protons, isolated subatomic particle in general aren't chemicals.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#118

Post by aranchelk »

sumtechguy wrote: post #99
mkoubaa wrote: post #15

Earlier quoted context omitted.

Beautiful yet terrifying. I'm glad that regex isn't something I'll ever have to touch.

I think it comes down to the syntax being used to make regex. It is borderline an assembly language level of making them. Better language tools would make it easier for people to grok. Basically instead of using chars like ?^()$ and the like lets use words people understand.

It’s not just the syntax. Regex isn’t directly composable (unless you just mash together strings). They cannot define nested structures, I.e. no recursion. They can’t maintain context.

We don’t need better language tools. Better parsers can, and already have, been implemented in libraries.

I’d have a look at parser combinators.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#119

Post by RandomWorker »

On Google I find that this is already used to treat diabetes: https://www.mayoclinic.org/drugs-supplements/semaglutide-sub...

here are the side effects;

Side Effects Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common Belching Bloated, full feeling Constipation Diarrhea Excess air or gas in the stomach or intestines Gaseous stomach pain Heartburn Indigestion Nausea Passing gas Stomach discomfort, fullness, or pain Vomiting Less common Recurrent fever Yellow eyes or skin Rare Burning feeling in the chest or stomach Stomach upset Tenderness in the stomach area Incidence not known Anxiety Blurred vision Chest tightness Chills Cold sweats Confusion Cool, pale skin Cough Darkened urine Difficulty swallowing Discouragement Dizziness Fast heartbeat Feeling sad or empty Headache Hives, itching Increased heart rate Increased hunger Irritability Lack of appetite Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs Loss of consciousness Loss of interest or pleasure Nightmares Pains in stomach, side, or abdomen, possibly radiating to the back Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue Redness of the skin Seizures Shakiness Skin rash Slurred speech Tiredness Trouble breathing Trouble concentrating Trouble sleeping Unusual tiredness or weakness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common Hair loss Rare Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site Change in taste Loss of taste Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#120

Post by binarymax »

jpc0 wrote: post #87
sgc wrote: post #71

Earlier quoted context omitted.

Regex is one of my favorite things to work with. It's surgery. I love having a very specific problem and a very sharp knife. What I hate is chasing down language or library bugs, or undocumented limitations. Of course I would hate it if I had never used it extensively. Its terseness is harder if you only have to pick it up occasionally.

Remember to get a license for your code https://regexlicensing.org/

> Licenses: “No regex licenses have been issued at this time.”

Perfect

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