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Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

medicalxpress.com

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Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#71

Post by sgc »

mkoubaa wrote: post #15
thom wrote: post #7

Delighted to discover this kind of breakthrough is based on a gnarly regular expression: https://github.com/Svensson-Lab/pro-hormone-predictor/blob/m...

Beautiful yet terrifying. I'm glad that regex isn't something I'll ever have to touch.

Regex is one of my favorite things to work with. It's surgery. I love having a very specific problem and a very sharp knife. What I hate is chasing down language or library bugs, or undocumented limitations. Of course I would hate it if I had never used it extensively. Its terseness is harder if you only have to pick it up occasionally.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#72

Post by droopyEyelids »

leereeves wrote: post #23
llamaimperative wrote: post #12

Earlier quoted context omitted.

And Novo (like many others) is already working on next-generation GLPs that’ll have new patent protection before Ozempic’s ends.

Even so, competition from other GLP-1 drugs and generic semaglutide should make prices and profits lower.

If the companies combined can meet demand

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#73

Post by SketchySeaBeast »

JKCalhoun wrote: post #48
xrisk wrote: post #40

Earlier quoted context omitted.

I’m not sure what this brings to the conversation. Are you able to attest to the correctness of what Sonnet claims?

I think we can be chill about it. For someone on the sidelines, mildly interested in the topic, an AI summary of the regex might be useful — and the person getting downvotes is saving some of us the time.

Yes, it might be misinformation, but it's convenient misinformation, is that the idea? And yes, it's true that a source like wikipedia could be too, but that has to withstand scrutiny to remain on the site, no such checks or balances in AI.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#74

Post by FrustratedMonky »

frankbreetz wrote: post #33
FrustratedMonky wrote: post #13

Earlier quoted context omitted.

Most people think "natural" means they can just go into backyard, dig up some root, and get this for free. But its " Gila Monster’s venom". So natural, but you aren't going to just go out and eat it like resveratrol from wine. At this point, 'natural', just means made from atoms, yes atoms are naturally occurring.

I may be missing some of your sarcasm, but "Gila Monster's venom" meets the strictest definition of natural.

Maybe, sarcasm was aimed at 'natural' being 'harmless' and/or common, because it is 'natural'.

When really, just being 'natural', doesn't mean anything really. There are poisons that are 'natural'.

Like resveratrol. Yes, it is natural and its in wine. But you need to drink many gallons a day to get enough to do anything. But people see 'Natural' and wine, and think it is a license to drink a lot.

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#75

Post by dleeftink »

sgc wrote: post #71
mkoubaa wrote: post #15

Earlier quoted context omitted.

Beautiful yet terrifying. I'm glad that regex isn't something I'll ever have to touch.

Regex is one of my favorite things to work with. It's surgery. I love having a very specific problem and a very sharp knife. What I hate is chasing down language or library bugs, or undocumented limitations. Of course I would hate it if I had never used it extensively. Its terseness is harder if you only have to pick it up occasionally.

You'll love this one then!

[0]: https://cardoni.net/parsing-proper-nouns-with-regex/

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#76

Post by dleeftink »

janfoeh wrote: post #41
dleeftink wrote: post #21

Earlier quoted context omitted.

It's not that bad. AutoRegex[0] and regex gen [1] make it more accessible than ever. [0]: https://www.autoregex.xyz/ [1]: https://regex-generator.olafneumann.org

Heh, I just fed autoregex a regex from one of my projects, and it simply times out. It comforts me to know that billion dollar LLMs have to chew on those just as much as I do.

A proper litmus test, what's causing the hang in your case?

Regex to me, is pattern finding and abstraction taken to the extreme. I like the challenge

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#78

Post by pjerem »

Willingham wrote: post #68
sweezyjeezy wrote: post #37

Earlier quoted context omitted.

They did specify "molecule". Certainly not every pharmaceutical occurs naturally, and other materials such as Teflon don't either.

This makes since, but I do like the idea presented before you, that humans are natural, and our evolution is natural, therefor the things that we make are natural too. But then where do you draw the line? If an alien drops a new element on earth, would this then be not ‘natural’? Or is it impossible for anything to not be natural?

Except the definition of natural is a human made concept which means "anything non-human made/consequence" ;)

Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

#79

Post by lores »

wincy wrote: post #64
lores wrote: post #50

Earlier quoted context omitted.

The drug does not directly affect muscle mass (unless you are already very lean), but heavy people are doing resistance training against their own body weight all the time, so they are strong in the absolute, even if not relatively. Weigh less and your muscles have it easier, so weaken, unless you keep them strong with exercise.

I’m not sure that’s exactly what’s happening with GLP-1 drugs. I lost 40 pounds very quickly on them and hurt my hip then my shoulder then my wrist. Felt like I was constantly getting muscle strains and random injuries. I started drinking a protein shake once a day and the random mysterious injuries stopped.

I'm on them too, and after being seriously grumpy for a while it dawned on me that not being hungry doesn't mean my body doesn't need satisfying food. I think it's easy to fall into 'don't need to eat, won't eat' and then get some form of malnutrition. I force myself to make good food and just eat less of it, so far it worked *fingers crossed*
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