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BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

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Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#161

Post by ryao »

bsder wrote: post #90
namuol wrote: post #39

Earlier quoted context omitted.

I don't think this analogy resonates particularly well with the drug manufacturing process. I would think in general the bulk of the expense of a drug comes from its R&D, not manufacture. The cost of manufacture probably varies wildly (with the most expensive being bespoke treatments), but as the talk shows, there have been many examples where a (relatively) simple-to-manufacture drug is kept from those who need it d…

> Will most drugs be easy to make at home? Probably not, but enough probably can be that I wouldn't dismiss the idea because of some rhetorical overreach. Ever watch a non-chef bake a cake? If you have, that experience should give you great concern about people playing with drug recipes. In addition, most drugs do not have a "nice" synthesis that doesn't leave a whole bunch of glop in the afterproducts. Distilling al…

People do not synthesize drugs on their own without any prior knowledge. They take university organic chemistry classes and then start synthesizing drugs. The cooking analogy would be studying at a culinary school prior to preparing pufferfish without a license.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#162

Post by IgorPartola »

esqui wrote: post #134
theossuary wrote: post #127

Earlier quoted context omitted.

It's crazy how DIY HRT and puberty blockers are now necessary to prevent trans kids from being mutilated by going through the wound puberty, then having to pay tens of thousands of dollars for reconstructive surgeries to fix maybe a fifth the damage.

Going through puberty isn't damage or mutilation, it's the process of development through which a child matures to an adult.

If you, as you are, were forced to go through puberty of the opposite sex as a child, would you have been ok with that? You could get into the trolley paradox of action vs inaction doing harm but really this is the same thing: do you force a person to go through the wrong puberty. The correct puberty isn’t damaging, the wrong one is.

As a cis man, I sure am happy nobody forced me to go through a female puberty.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#163

Post by esqui »

IgorPartola wrote: post #162
esqui wrote: post #134

Earlier quoted context omitted.

Going through puberty isn't damage or mutilation, it's the process of development through which a child matures to an adult.

If you, as you are, were forced to go through puberty of the opposite sex as a child, would you have been ok with that? You could get into the trolley paradox of action vs inaction doing harm but really this is the same thing: do you force a person to go through the wrong puberty. The correct puberty isn’t damaging, the wrong one is. As a cis man, I sure am happy nobody forced me to go through a female puberty.

You are asking a question of science fiction.

It is impossible for anyone to undergo the puberty of the opposite sex because, obviously, they are not of that sex.

As you are male, there is no method by which you could have gone through female puberty. So your hypothetical of this being forced upon you is nonsense.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#164

Post by yinser »

ryao wrote: post #119
yinser wrote: post #99

Earlier quoted context omitted.

You are directionally correct but the top of the line chisels are in fact hand made in Japan and I suspect the same for knives. Lee Valley and some other higher end manufacturers make some damn fine chisels but chisels are hand tools and I would guess 9/10 woodworkers who use chisels will choose hand made Japanese chisels over any factory manufactured tools.

Isn’t the main thing that makes a chisel better or worse the material quality, such that regardless of whether it is hand made or factory made, the chisel made of superior material is better?

Selection of metal, lamination, presence of a ura (裏), handle material, the ability to make a new handle and attach it to the original metal. A metal chosen for an extreme sharpness may be terribly difficult to sharpen, a metal easy to sharpen may not hold an edge for long.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#165

Post by yinser »

yinser wrote: post #164
ryao wrote: post #119

Earlier quoted context omitted.

Isn’t the main thing that makes a chisel better or worse the material quality, such that regardless of whether it is hand made or factory made, the chisel made of superior material is better?

Selection of metal, lamination, presence of a ura (裏), handle material, the ability to make a new handle and attach it to the original metal. A metal chosen for an extreme sharpness may be terribly difficult to sharpen, a metal easy to sharpen may not hold an edge for long.

Most factory chisels are not laminations like hand made Japanese ones are. They are just a single alloy.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#166

Post by ryao »

portaouflop wrote: post #54
NeutralCrane wrote: post #33

Earlier quoted context omitted.

Given that the application here is molecular chemistry aimed at targeting human biology, one of the few problems equally complex as computer chips, I would say their analogy is far more appropriate than a hammer .

Creating a medicine such as the ones mentioned in the talk is FAR more simple than creating microchips - as a starter you don’t need a billion dollar worth clean room and equipment as they clearly demonstrate. So yea human biology is as complex if not more complex I agree - creating medicine after a proven recipe is not.

You do not need “a billion dollar worth clean room and equipment” to make chips. You just need a garage and a bunch of old equipment. Even high school students can make microchips:

https://spectrum.ieee.org/the-high-school-student-whos-build...

As your “creating medicine after a proven recipe” remark, that is not how things work. The way it usually works is that you study organic chemistry in college and then you work out a recipe yourself based on the chemical formula. You do not follow a recipe from someone else because recipes are often trade secrets. At least, that is what I took away from studying organic chemistry in college. Well, that and a remark by the professor that those making illicit drugs take that course before getting started.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#167

Post by IgorPartola »

esqui wrote: post #163
IgorPartola wrote: post #162

Earlier quoted context omitted.

If you, as you are, were forced to go through puberty of the opposite sex as a child, would you have been ok with that? You could get into the trolley paradox of action vs inaction doing harm but really this is the same thing: do you force a person to go through the wrong puberty. The correct puberty isn’t damaging, the wrong one is. As a cis man, I sure am happy nobody forced me to go through a female puberty.

You are asking a question of science fiction. It is impossible for anyone to undergo the puberty of the opposite sex because, obviously, they are not of that sex. As you are male, there is no method by which you could have gone through female puberty. So your hypothetical of this being forced upon you is nonsense.

In that case I fully encourage you to try HRT for the opposite sex. You fully believe it will have no effect on you so please prove that point.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#168

Post by esqui »

IgorPartola wrote: post #167
esqui wrote: post #163

Earlier quoted context omitted.

You are asking a question of science fiction. It is impossible for anyone to undergo the puberty of the opposite sex because, obviously, they are not of that sex. As you are male, there is no method by which you could have gone through female puberty. So your hypothetical of this being forced upon you is nonsense.

In that case I fully encourage you to try HRT for the opposite sex. You fully believe it will have no effect on you so please prove that point.

It would have an effect, but that effect is not the puberty of the opposite sex. This would be an impossible outcome.

You are male. If you took estrogen - either now, or as a child - you would not begin to menstruate, you would not experience changes to the vaginal surface, you would not start to ovulate, and so on. Female puberty is a developmental process that only applies to those who are female.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#169

Post by sudosysgen »

93po wrote: post #70
cjbgkagh wrote: post #66

Earlier quoted context omitted.

Modafinil 100mg morning and Amitriptyline 75mg at night helps with dysautonomia, though modafinil can exacerbate gut issues. Using weaker ligands helps with working with the natural cycles of the body instead of against it. Low Dose Naltrexone. A fairly high dose of TUDCA and DIM. DIM (3,3'-Diindolylmethane) is a relatively non-toxic selective AhR modulator. Ipamorelin + ModGRF. VIP peptide. A fairly low dose Semaglu…

What is the mechanism of Naltrexone in reducing fatigue? It seems like fatigue and sleepiness is a common side effect. I had really high hopes for modafinil in treating my long-life fatigue issues as well as helping with my severe ADHD since I can't tolerate or access traditional stimulant medication for it rignt now. It was amazing for a week or so but quickly stopped having an effect unless I took 400mg a day, and…

Naltrexone is a very weird drug, as it's both an agonist and antagonist of it's target receptor (but mostly an antagonist). As a result paradoxical effects are to be expected.

Re: BioTerrorism Will Save Your Life with the 4 Thieves Vinegar Collective [video]

#170

Post by scarecrowbob »

ryao wrote: post #166
portaouflop wrote: post #54

Earlier quoted context omitted.

Creating a medicine such as the ones mentioned in the talk is FAR more simple than creating microchips - as a starter you don’t need a billion dollar worth clean room and equipment as they clearly demonstrate. So yea human biology is as complex if not more complex I agree - creating medicine after a proven recipe is not.

You do not need “a billion dollar worth clean room and equipment” to make chips. You just need a garage and a bunch of old equipment. Even high school students can make microchips: https://spectrum.ieee.org/the-high-school-student-whos-build... As your “creating medicine after a proven recipe” remark, that is not how things work. The way it usually works is that you study organic chemistry in college and then you wor…

This is an interesting comment, because before you mentioned it I did not even consider DIY chip fab was a possibility.

In the context of access to cheap mass production, it would of course be silly to use the DIY product of that professionally.

In the context of "having zero access" to the technology, then the hand-produced products can be better than nothing, especially if the "no access" alternative is heinous or deadly in its own right.

It's kind of a micro-scale version of the larger discussion, perhaps?

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