901–910 of 1001 posts
I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…
In the future, this would be indistinguishable from an ad.
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re: 1, there are plenty of people who take some medication at some interval for most of their life. People with ADHD, people with type 1 diabetes, most women, ... why do we find that totally unproblematic, but as soon as it's medication to help with obesity (which is a serious medical condition in its own right) it's suddenly such a big problem? EDIT: And to be clear, there may be specifics with these particular drug…
> People with ADHD, people with type 1 diabetes, most women, ... why do we find that totally unproblematic ADHD medicine is highly problematic. The medications are controlled to ridiculous levels, and there are strong social stigmas against both the condition and the disorder.
It will be interesting to see how health insurance companies deal with Ozempic. A few days ago a top article on HN posed the question: Millions of Americans could benefit from drugs like Ozempic; will they bankrupt the healthcare system? Of course there are many health benefits to losing weight. Given there are clear, healthy, non-drug assisted ways to lose weight, should drug-assisted weight loss be considered an 'e…
The UK gets their semaglutide meds from Novo Nordisk for ~£75 to ~£175 depending on the dosage for a month supply. It starts at ~$1k in the US. Tons of other countries with similar or better negotiated pricing.
Instead of implementing a system that would allow our government to have leverage to prevent this sort of thing from happening to begin with, we sit around, wait for enough everyday people to get screwed over by it to start raising a ruckus, and then some federal agencies fine you a infinitesimal amount compared to the profits you made, your CEO goes and testifies in front of Congress for a few minutes, and even on the most positive outcome side, they then reduce the prices, and basically never to the levels they negotiated with other countries.
Meanwhile they keep the overwhelming amount of money they made selling it to Americans at outrageous prices. And hell - that's capitalism, baby! I can't say I have any expectation of a company behaving any differently when this is a valid way to operate.
So we gotta make it not a valid way to operate.
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Have you every using a calorie/macro tracking app like My Fitness Pal or Cronometer? I was never successful losing weight until I scanned, weighed, and measured every single thing I put into my body and stuck to the target calories and macros entered into the app. Just being aware of exactly how much I was eating was often enough to find the motivation to control volume.
>> I scanned, weighed, and measured every single thing I put into my body Not being snarky, but is this truly "better" than a single weekly injection - 10 seconds and done for the week? I do think our wider society sees medications for overeating as "cheating". Perhaps we might benefit from rethinking that.
Yes, obviously. I'm stunned that it needs to be said, but since it apparently does:
1. You propose taking a medication regularly which is probably completely unnecessary, and paying for it regularly. (This was worse with "metabolism boosters" etc. since the patient would be paying for the medication to have the privilege of eating more, and thus paying more for the extra food.)
2. Knowing what you eat, and being able to denominate it in calories, is knowledge. I thought we were hackers here? My experience has been that ordinary people have some truly absurd ideas about how fattening certain things are or aren't, or about how much they're actually eating, or about what healthy daily intake ranges, portion sizes etc. look like. (They also have absurd ideas about how much it costs to "eat healthy", as well as about the connection between "healthy" food and caloric intake.)
One trend I noticed, whenever this topic is discussed in public forums, it attracts a lot of negativity from "just exercise and eat less" crowd (generalizing here). I wonder why it caused so much negative reaction? On the surface it shouldn't matter much, since it does not appear to harm ones who found a way to maintain healthy body without drugs. Yet it reliably causes a quite noticable number of folks to be quite a…
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Educating people will hardly work. Bans on junk foods at government level might.
If educating people didn't work, we'd all be drinking cocaine soda and burning leaded fuel. I mean, there's a reason things have generally greatly improved over time for most of humanity. We know more things and act upon that knowledge. This applies to basically every single thing humans do. Maybe one day we won't be drinking sugar water and adulterating ~every piece of food on the shelf with high-fructose corn syrup…
When the person you are arguing with is saying that government induced bans would probably help more, and your are arguing they're wrong and your two examples were resolved by government induced bans, you're going about arguing in a very strange way.
https://ourworldindata.org/grapher/share-of-adults-defined-a...
Are these drugs good? I'm not sure, but I think a lot of these drugs seem to be reducing how much people eat -- helping people break from the life time of bad habits they've learned since childhood from their parents/friend/media/fast food industry. I don't know if eating habits in childhood can embed themselves as permanent alterations to the person's biology, like myopia in eye sight. But if it does, then these drugs might be the "glasses" equivalent for metabolism/eating. Citation needed. But if so, then let's see if we can learn from our mistake with how glasses are perscribed, and instead of leaving children in the same environment that results in the development of the same diagnosis which will then require them to also take ozempic/use glasses/etc, and instead raise them so that they never develop the problem in the first place.
Note: even the myopia link is still being researched I believe, but more papers seem to be showing this potential relationship.
Variables:
- unhappiness increasing (citation needed)
- low income people buy cheap, processed food
- middle class people eat out at restaurants more since they can afford it
- upper class people likely the healthiest?
- unhealthy processed foods have become regular standard snacks (eg chips, cola) taking the place of healthy snacks like fruits/veg
- portion size increases in the home and at restaurants
- the fast food industries incentive to get people to eat more
- people developing bad eating habits at young ages, which are significantly harder to break later in life and could potentially result in permanent changes to metabolism (similar to how myopia has been linked to children spending a lot of time inside/books/screens)
- low availability of healthy fresh food -- when was the last time you got fruit as a snack in the middle of the day? Or for dessert?
- reduced mobility; sitting jobs, order to your door, work from home
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From my understanding GLP-1 agonists can actually modulate the reward pathway reducing people's appetite for toxic diets. We're not socially caught up yet to this information. I suspect there are folks who believe that regardless of similar outcome (reduction of toxic diet), that changing diet without medication is superior to those who change their behavior through pharmacological intervention. It's like the pre-199…
You can literally do the same thing by eating a healthy diet for 2-4 weeks.
Obesity rates are on the rise in all modern countries, and although the rate of growth is different, in no country does it show any signs of slowing down. https://ourworldindata.org/grapher/share-of-adults-defined-a... Are these drugs good? I'm not sure, but I think a lot of these drugs seem to be reducing how much people eat -- helping people break from the life time of bad habits they've learned since childhood fro…
To anyone thinking that exercise will fix anything: I've owned a Concept 2 rowing machine since 2005. In that time I've done an average of 100 workouts per year, for a total of over 35 days of rowing. Some workouts were relatively easy 120bpm heart rate; some were at a relatively brutal 160bpm. Concept 2 estimates I've burned just over 600,000 calories, or about 1,000 Big Macs. Could I have eaten 1,000 Big Macs in 19…
> I've owned a Concept 2 rowing machine since 2005. Well here’s your problem. You should’ve bought barbell 20 years ago. Or at least a couple of kettlebells.