Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

How long til we're all on Ozempic?

asteriskmag.com

Post reply on HN
Print view View original

741–750 of 1001 posts

Re: How long til we're all on Ozempic?

#741

Post by fortran77 »

arijo wrote: post #696
fortran77 wrote: post #675

Earlier quoted context omitted.

This is true, but fat people have a hell of a time cutting out all carbs. For many of them, they'll eat the "low carb" option, and then have an occasional binge and it negates any benifits of low carb, and doesn't put them in ketosis, etc. I strictly maintain my weight. If I catch it going over over 155# (I'm a 5'10" 61 year3 old male) I'll do a strict cut. And I know that either strictly counting calores OR going to…

I’m 1.78m, 50 years old, my initial weight 2 month ago before I started the keto diet was 154kg and two months later I’m almost 130kg. Eating the same amount of calories as before.

Yes. But a real keto diet, where you are in ketosis, is impossible for most fat people to follow. They will inevitably cheat (“tee hee hee! It doesn’t count if it’s birthday cake! I’m so naughty”) and be in ketosis.

Re: How long til we're all on Ozempic?

#742

Post by nessguy »

robohydrate wrote: post #299

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

I'm with you on this, tirzepatide has been life changing for me. I've struggled with my weight my whole life and I can actually imagine a future where I lose enough that I'm no longer ashamed of my weight.

I've been on tirzepatide for just over a year now. Before that, I managed to lose 6% of my body weight over the previous year. With tirzepatide, I've lost an additional 17% of my body weight, for a total of 23% over two years.

Tirzepatide isn't a magic drug that just makes you lose weight, it simply makes it much easier to avoid overeating.

It makes the difference between being so hungry that I can't fall asleep and having the ability to just go to sleep.

Re: How long til we're all on Ozempic?

#743

Post by __turbobrew__ »

andrewla wrote: post #239

I think Ozempic is a treatment of a symptom but not the underlying condition, but unlike many of the posters here, I do not think the underlying condition is "obesity". The below is mostly speculation. Research especially into people with healthy body weight seems to indicate that there is something going on that is causing widespread obesity. That is, there's some sort of environmental "GLP-1 Turbocharger". Maybe it…

My bet is pollutants in the water. The further up the waterstream (and higher elevation) the thinner on average people get.

Re: How long til we're all on Ozempic?

#744

Post by doublerabbit »

0xcde4c3db wrote: post #732
asciimov wrote: post #723

Earlier quoted context omitted.

Coke and Pepsi started using HFCS in 1980. I’d be curious about side effects of the Depression and WW2 that took an extra generation to show up.

> I’d be curious about side effects of the Depression and WW2 that took an extra generation to show up. While there might be a time span involved that could be described that way, as far as I've read there weren't any statistics that were "generational" in the usual sense of the term. Obesity rates started rising among all age groups at roughly the same time.

Hormones in meat. And I expect the women's pregnancy pill plays a part in this as well to why we have over emotional disorders. This has all originated from the 70's both.

The demand for cattle are so high that they force feed them growth hormones. You eat the meat, you end up with injected mutations and then over generations you then end up with people with growth hormones and obesity because of.

How can hormone bated meat not affect the human body?

As well, women have been taking a pill, since the 70's, it does its thing, they pee. That mixes with the water and overtime pollutes the generations.

Re: How long til we're all on Ozempic?

#745

Post by dahart »

larodi wrote: post #680
OptionOfT wrote: post #420

As someone who struggled with their weight his whole life, this medication is a god send. My wife and I cook every evening. We never eat food made in a factory. We buy raw products and spend a good amount of time every day cooking them. Every morning I wake up and go on a 5 mile hike. And still weight kept on coming on. Worse yet, I am on ADHD medication, which are amphetamines and actually make you lose weight. Yet.…

Perhaps the first person on HN who actively and without shame pays attention to the fact that Adderall is a very nice amphet cocktail. Surprising though you don't loose wait with it, sad also given the circumstances. But I envy you a little cause such ADHD boost is only illegal in EU. Sometimes I wonder if it was a some neat trick by US gov to diagnose and put 1/5 of the population on amphetamines (2024 data +60mil p…

> 1/5 of the population suddenly increases output

I’ve heard studies show Adderall doesn’t help people without ADHD… googling now seems to confirm. Apparently lots of people, especially college kids, take it thinking it will help, but it actually can slow them down.

Re: How long til we're all on Ozempic?

#746

Post by unlikelytomato »

mrshadowgoose wrote: post #544
OptionOfT wrote: post #420

As someone who struggled with their weight his whole life, this medication is a god send. My wife and I cook every evening. We never eat food made in a factory. We buy raw products and spend a good amount of time every day cooking them. Every morning I wake up and go on a 5 mile hike. And still weight kept on coming on. Worse yet, I am on ADHD medication, which are amphetamines and actually make you lose weight. Yet.…

> Why do we find it acceptable to help people who struggle with alcohol abuse, or nicotine addiction, or opioid addiction, but not to help people who struggle with food abuse? "Getting fit and staying fit" is a form of social capital, because it's extremely hard and only within reach of a small portion of the population. "Being fit" is strongly aligned with "being attractive" which confers all sorts of cross-cutting…

I would say my concerns are far more in the range of downstream effects from the medication. Specifically, I am concerned with muscle retention. Concerns aside, it's a little hard of an argument to swallow having visited many other countries where these things are simply not an issue. How can it be argued that the cause is anything other than behavior when so many others are doing just fine? There is more to this story than painting people as evil.

Re: How long til we're all on Ozempic?

#748

Post by smugma »

Many in the thread have asked “why get off the drug?”

Regeneron is pursuing its own version of a magic weight loss drug and is arguing that the current batch of GLP1 drugs reduce muscle mass, which is one of the most important things to maintain as one passes middle age (comorbidity etc.)

https://www.ft.com/content/094cbf1f-c5a8-4bb3-a43c-988bd8e2d...

The co-founder of Regeneron has warned that blockbuster weight-loss drugs could cause “more harm than good” unless the rapid muscle loss associated with the treatments is solved...

Clinical studies suggest that patients treated with the new class of weight- loss drugs, known as GLP-1s, lose muscle at far faster rates than people losing weight from diet or exercise, exposing them to health problems, said George Yancopoulos, who also serves as Regeneron’s chief scientific officer.

Re: How long til we're all on Ozempic?

#749

Post by dleink »

chrismarlow9 wrote: post #253
apsec112 wrote: post #22

Earlier quoted context omitted.

Saying that the cure for obesity is to eat less is like saying that the cure for heroin addiction is to stop using heroin. It's both clearly true, and also useless.

The cure is to teach from an early age about impulse control, moderation, and how to spot signs of addiction in yourself early. This goes for: Social media Drugs and alcohol Food Or literally any other addiction. I don't think this is a useless thing to discuss.

The presently addicted and obese thank you for your service to the future.

Re: How long til we're all on Ozempic?

#750

Post by archsurface »

jart wrote: post #665
archsurface wrote: post #601

Earlier quoted context omitted.

You mention types of food but not quantities. A boat load of healthy food is still going to have an effect. Also, I for one don't consider walking to be exercise. It's fake exercise for people who don't like exercise to claim they exercise. My reason is that I cycle for eight months of the year then walk during the rainy months. By the end of the rainy months I get back on the bike and my fitness level is catastrophi…

What about someone who's carrying 100+ pounds of excess body weight? Would you consider walking to be fake exercise for them? I'd say that's a more heroic workout than joy riding.

I've seen such people jogging - intervals - short jog, short walk, short jog, ... They didn't look comfortable, but when I'm cycling uphill toward the end of a hard ride with nothing left in the burning legs I start grimacing too. What do you want? No free lunch.
Post reply on HN