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How long til we're all on Ozempic?

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Re: How long til we're all on Ozempic?

#651

Post by rootusrootus »

0xcde4c3db wrote: post #602

I think we desperately need to answer the question of why GLP-1 agonists are so effective, and particularly whether it's counteracting something in the environment that has been acting to reduce GLP-1 (or other glucagon-related pathway) activity without us realizing it. The obesity data practically screams that something happened in North America ca. 1980 that messed up our metabolisms, and it may have spread to Euro…

Europe has been climbing at a steady rate since at least 1975.

https://www.europeandatajournalism.eu/cp_data_news/europe-fa...

Re: How long til we're all on Ozempic?

#652

Post by rootusrootus »

avelis wrote: post #643
0xcde4c3db wrote: post #602

I think we desperately need to answer the question of why GLP-1 agonists are so effective, and particularly whether it's counteracting something in the environment that has been acting to reduce GLP-1 (or other glucagon-related pathway) activity without us realizing it. The obesity data practically screams that something happened in North America ca. 1980 that messed up our metabolisms, and it may have spread to Euro…

One aspect is that the US food system as a crap ton of UPF.

How does that cause the rest of the world to also have decades-long steadily increasing obesity rates?

Re: How long til we're all on Ozempic?

#653

Post by TacticalCoder »

lol768 wrote: post #319

> How long til we're all on Ozempic? It's genuinely quite depressing that so many people in the United States have a weight problem that the overwhelming majority of the population would benefit from this and headlines including "we are all" are not inaccurate. I don't think other countries are necessarily perfect here, but 74% of Americans don't have a healthy weight when you look at their BMI. That's a staggering s…

> It's genuinely quite depressing that so many people in the United States have a weight problem

I agree.

I'm 51 y/o and still totally fit. Always have been. I am completely in control of what my body intakes. I can fast for 12 hours from waking up until dinner: I do it regularly (as in at least five times a month, probably a bit more).

I did do sport like crazy when I was young but don't even bother that much. Some walking, taking the stairs instead of the elevator, some bicycling, some tennis. But at a gentle pace. "More haste, less speed" (thousands of years old saying).

It's crazy to poison oneself to the point where another poison (that Ozempic drug) is needed to counter the first poison.

I'm not saying it cannot help but sadly there's no way to say it nicely: if you need that, your body controls your mind.

It should be the contrary.

> Something is seriously wrong societally ...

The biggest issue to me is we live in societies (not just in the US) where we victimize everyone. Nothing is never nobody's fault. We find excuses for just about everything.

We should go back thousands of years and read the classics: "healthy mind in a healthy body". Greek philosophers had already figured that in the Antiquity.

Mind over body.

Re: How long til we're all on Ozempic?

#654

Post by presentation »

llamaimperative wrote: post #256
gcr wrote: post #229

Earlier quoted context omitted.

If you have an open mind, I'd like to assign you some homework if you like. Take a look around r/zepbound and count the following: 1. Posts from folks who diet+exercise, or who have tried diet/exercise and nothing's worked so they then turned to Zepbound ("excited to hit the gym," "my diet is finally starting to work with Zepbound" and similar) 2. Posts from folks who haven't tried diet/exercise and turned to Zepboun…

GP isn't talking about self-control, they're talking about the fact we've created a system that requires obscene amounts of self-control if you wish to maintain physical health. People in the 50s weren't slimmer because they had ironclad determination to stay such.

Living in Japan has made it clear to me that cultural attitudes towards food make all the difference. It’s not like there’s a dearth of delicious things here, but obesity rates are more or less a rounding error.

Re: How long til we're all on Ozempic?

#655

Post by aucisson_masque »

So basically eat shit and then take drugs to lose the weight you accumulated because of your bad diet ??

Am I the only one to realize how this is so wrong?

You would think When a pipe leaks, you fix it. You're not going to put a basin under it, empty it every day, pay for a new basin every few week and continue to have your damn pipe leak.

Oh man... If only you could teach people how to eat better instead.

Re: How long til we're all on Ozempic?

#656

Post by rootusrootus »

sensanaty wrote: post #595

[flagged]

I don't like processed foods and sugar in anything more than minimal quantities makes me ill. But I still get too many calories, at least as evidenced by my waistline.

Are you sure the insanity isn't the assumption that it's just insufficient willpower or poor habits?

Re: How long til we're all on Ozempic?

#657

Post by rootusrootus »

reducesuffering wrote: post #611

One very understated aspect that I haven't seen brought up: If part of the obesity epidemic is trying to consume food to make up for nutrient deficiencies, these drugs will only worsen these nutritional deficiencies. You'll lose weight short-term, but long-term sabotaged your body trying to attain these. We've seen declining vitamins and minerals in natural food (industrial produce growth). Maybe some people make it…

> If part of the obesity epidemic is trying to consume food to make up for nutrient deficiencies

Is there evidence to support this hypothesis?

Re: How long til we're all on Ozempic?

#658

Post by pkulak »

dfxm12 wrote: post #170

Instead of a system that makes these drug available for purchase, I'd rather live in a system that promotes healthy food and active behavior. Unfortunately, I have to drive everywhere, work too many hours to have free time for recreation and have no idea which government subsidy is going to help big ag likely at the expense of my health. All things being equal, I'd prefer to spend less money on prescriptions and have…

I run three miles a day, never drive anywhere (bike or bus), eat reasonably healthy, and I'm still 20 pounds overweight. And what really scares me is that running is the only exercise I enjoy and if my weight fluctuates up just 5 pounds or so, I start getting hip/knee/foot etc pain. If I gain 10 pounds through some lapse in morality, I won't be able to run anymore and I'm cooked. If that happens, I'm banging down my doctor's door for a pill.

Re: How long til we're all on Ozempic?

#659

Post by beeboobaa3 »

unclad5968 wrote: post #585
mrshadowgoose wrote: post #544

Earlier quoted context omitted.

> Why do we find it acceptable to help people who struggle with alcohol abuse, or nicotine addiction, or opioid addiction, but not to help people who struggle with food abuse? "Getting fit and staying fit" is a form of social capital, because it's extremely hard and only within reach of a small portion of the population. "Being fit" is strongly aligned with "being attractive" which confers all sorts of cross-cutting…

In what ways is fitness not within reach for a large portion of the population?

just look around outside

Re: How long til we're all on Ozempic?

#660

Post by makeitdouble »

lottin wrote: post #577
mlsu wrote: post #381

Earlier quoted context omitted.

My view about obesity has shifted dramatically since Ozempic came out. Before this, I didn't think about it too much (I am not obese myself). I notice now that there is a LOT of judgement, bias(?), around obesity, that people, obese or not, carry with them [1]. I certainly carried that bias, and the reason I noticed it was because Ozempic is literally an external substance that you take that simply makes obesity go a…

It's not just willpower but also lifestyle. It's rare for people who are physically active, and have a balanced diet, to suffer from obesity. I can eat A LOT without putting on a ton of weight, and it's because the types of foods I eat and because I do strength training, which means have a fair amount of muscle mass which acts as metabolic furnace. I'm a little overweight, at the moment, but it'd take a lot of effort…

> It's rare for people who are physically active, and have a balanced diet, to suffer from obesity.

Looking at it from the other angle: can obese people be active and have a balanced diet ?

The answer is yes. In particular you can be obese and maintain your BMI at the same level while being fairly active and not overeating, that happens a lot with people gaining weight and reacting to it, but without going down.

From the pool of people physically active and with a balanced diet, what's the split of obesity is a question I don't have the answer to, but the lifestyle part doesn't look like a good differenciator to me if we're solely focusing on current obesity.

PS:if you eat a LOT more without gaining much weight, imagine eating a LOT less and see very little change.

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