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How long til we're all on Ozempic?

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Re: How long til we're all on Ozempic?

#391
post #381

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

My view about obesity has shifted dramatically since Ozempic came out. Before this, I didn't think about it too much (I am not obese myself). I notice now that there is a LOT of judgement, bias(?), around obesity, that people, obese or not, carry with them [1]. I certainly carried that bias, and the reason I noticed it was because Ozempic is literally an external substance that you take that simply makes obesity go a…

Obesity is a side effect of the industrial food production system in advanced economies that is slowly spreading all over the globe.

How about alcohol and smoking ? Is that the same as obesity then

Re: How long til we're all on Ozempic?

#392

Earlier quoted context omitted.

GP isn't talking about self-control, they're talking about the fact we've created a system that requires obscene amounts of self-control if you wish to maintain physical health. People in the 50s weren't slimmer because they had ironclad determination to stay such.

In my experience fitness is less about self control or will power and more about creating routines that lead to fitness. For example, I have a routine of going to a group fitness class at my gym in the morning. I don't need to summon willpower, I just have a morning routine that involves doing x thing at y time. No thought required. Given the abundance of options for fitness classes and meal plan services, you really…

> Given the abundance of options for fitness classes and meal plan services...

This is part of what's fucked up about modern American lifestyles.

We shouldn't be promoting layering healthy behaviors (fresh foods and exercise) on top of our default lives -- we should be doing a better job of engineering our environment to make those things the default for all people.

F.ex. what if we highly taxed automobile entry into urban cores and shopping districts?

Re: How long til we're all on Ozempic?

#393
post #355

I'd think it more likely that it'll be one of the next generation drugs, but I do agree with the premise that it will be really common. A few weeks ago I started a low dose of tirzepatide (aka Mounjaro, aka Zepbound) and the side effects are interesting. The biggest negative, which just takes adjustment, is drastically lower stomach capacity. Used to be that two eggs and two pieces of toast was breakfast. Now I bette…

>I might switch to a twice-a-week split dose at some point to ease the peaks and valleys. If you're willing to shoot up more often it moderates the effects better.

I definitely am. That first shot took a solid 30 seconds and three false starts before I could jab it in, but it turns out to be a great big nothingburger once you do it. Can barely even feel it, nothing like the intramuscular shots like flu/etc. I could do this shot as often as necessary without batting an eye.

Re: How long til we're all on Ozempic?

#394
post #319

> How long til we're all on Ozempic? It's genuinely quite depressing that so many people in the United States have a weight problem that the overwhelming majority of the population would benefit from this and headlines including "we are all" are not inaccurate. I don't think other countries are necessarily perfect here, but 74% of Americans don't have a healthy weight when you look at their BMI. That's a staggering s…

We're all depressed and overworked and have been for decades. Food is an escape

Re: How long til we're all on Ozempic?

#396
post #170

Instead of a system that makes these drug available for purchase, I'd rather live in a system that promotes healthy food and active behavior. Unfortunately, I have to drive everywhere, work too many hours to have free time for recreation and have no idea which government subsidy is going to help big ag likely at the expense of my health. All things being equal, I'd prefer to spend less money on prescriptions and have…

The government isn't going to help you.

This evening, go for a one minute walk.

Tomorrow evening do the same.

Next evening do the same.

Repeat.

The journey of a thousand miles begins with the first step.

Re: How long til we're all on Ozempic?

#397
post #276

Earlier quoted context omitted.

The more important point the comment you're replying to makes is not "what if people could diet and exercise" - i.e. accept the modern American lifestyle as given, plus force yourself to go to the gym and eat chicken and broccoli - but rather that the modern American lifestyle in fundamentally structured to lead to people being overweight. Instead of being forced to drive everywhere for the most basic possible human…

IMHO price of calories is the only thing that needs to change. All the talk about wholesome locally grown foods vs. processed industrial stuff is just moralizing and posturing, when the metric that matters is the price. Just look at Coke, which is arguably not even a good example because of pre-war price fixing, but still it costs half as much as in 1950 when adjusted for inflation.

Tax each calorie $1 and give everyone $2000/day.

(You’ll quickly end up with another underground white powder economy though…)

Re: How long til we're all on Ozempic?

#398

My biggest fear is either there will be long term negative consequences to Ozempic et al, and a huge swath of the population will be dealing with issues 30 years form now - OR - there will be some long term positive consequence to using Ozempic et al, and I'm not getting any of the benefits because I'm not overweight.

OR - there will be some long term positive consequence to using Ozempic et al, and I'm not getting any of the benefits because I'm not overweight

Who the fuck cares? If you're not overweight and are reasonably then you're already winning in physiological terms. If you can maintain a good quality of life into old age and then die, what more do you want? Going through life worrying about whether you're missing out on some marginal health benefit from the drug-of-the-moment is neurotic.

Re: How long til we're all on Ozempic?

#399

I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…

Is the official recommendation that you continue to take it for the rest of your life? Or, is there a schedule to "wean" people off of it?

Studies have show most people rapidly regain the weight once they stop taking GLP-1 drugs.

The dysfunctional biochemical processes that contributed to overeating are still present if you discontinue the drug. Your body has a natural set-point for the weight it wants to be at, and the hunger and food noise comes right back as your body tries to get you back to your old weight.

It's possible that after after a long enough time at a healthy weight your body's natural weight set-point will regulate itself back down. But this process take years.

Re: How long til we're all on Ozempic?

#400

Earlier quoted context omitted.

Tirzepatide and Semaglutide are both known to reduce addiction / substance ingestion. I noticed I was just less interested in Alcohol when I started on Wegovy, and didn't realize it's a common effect until much later. I retained most of my disinterest after going off, too, FWIW.

Sounds like a miracle drug that helps with all afflictions that come with our modern life/sedentary living.

I'd say it's the opposite - if you don't exercise you end up skinny fat which is metabolically unhealthy as well. It helps with super accessible dopamine hits I guess - which is awesome - but need to combine it with exercise for maximum benefit.

I wouldn't be surprised if they come up with a drug for that that's more sideffect free than testosterone/ derivatives. Lean and ripped cocktail

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