51–60 of 148 posts
This looks like a windows only app, here's another source, that runs on the browser. https://www.gkbrk.com/wiki/caffeine-halflife/ . Not affiliated, I just use it Also, Smokers metabolise caffeine faster. https://pubmed.ncbi.nlm.nih.gov/657717/
Here's the thing: never mind getting to bed, that will happen when you are tired enough. How about sleeping through the night? A different function with different math. My model is caffeine is well-known for having a half-life, from three to six hours depending. That means a geometric fall in effective caffeine in your system after you go to sleep (you don't continue ingesting caffeine in your sleep do you? Sleep-bre…
You may enjoy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541543/ which explains more than I can
I've been replacing most of my morning coffee with yerba mate. Yerba Mate isn't a roller coaster ride of highs and lows but a smooth, elevated sense of caffeine alertness.
I would have like that, but trialing it for several weeks it seems too much effort and caution is required (I.e. easier to ruin a brew). I take Does it get much better with experience?
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I would have like that, but trialing it for several weeks it seems too much effort and caution is required (I.e. easier to ruin a brew). I take Does it get much better with experience?
There’s also Guayusa which is pretty much same routine as tea
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Actually went through fullgenomes.com - they apparently don't offer exome sequencing any more but for under $1200 getting your genome sequenced is interesting. If you ask anyone who works in genetics, though, they'll advise you never to do it. It can be bad news, but there's virtually no good news there.
It's useful to have as a resource that you can dip into; for instance to check a specific thing like "how fast do I metabolise caffeine (bad example as youc can get that from a SNV checking service like 23&Me. However, never ever EVER dump your whole genome into a program that will output every match for some potential condition. Now that's not for the reason you might immediately think ("Oh no look at all the bad st…
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Probably though 23andMe and the CYP450 enzyme CYP1A2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212886/
Actually went through fullgenomes.com - they apparently don't offer exome sequencing any more but for under $1200 getting your genome sequenced is interesting. If you ask anyone who works in genetics, though, they'll advise you never to do it. It can be bad news, but there's virtually no good news there.
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And there are at least 3 different metabolic rates for caffeine, rapid, standard, and slow. As a holder of the slow gene, none of these calculators work for me since for me caffeine has a ~9 hour half life. Caffeine after about 11 am is a bad plan.
Pretty sure there's some age related effects too. Over the last ~20 years I've gone from being happily able to drink coffee after dinner, through not being able to drink it after 5pm or so, and now to having the espresso machine automatically shut off at 2:30pm - otherwise my sleep quality plummets. I'm 57 now, I started noticing poor sleep related to late night coffee in my mid 30s. I do got fairly hard earlier in t…
Coffee must have a very different half life in me. Even 400mg in the morning won’t completely leave my system over 24 hours. So it seems to gradually build up and by the fourth day of 400 mg I can’t sleep at all.
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And there are at least 3 different metabolic rates for caffeine, rapid, standard, and slow. As a holder of the slow gene, none of these calculators work for me since for me caffeine has a ~9 hour half life. Caffeine after about 11 am is a bad plan.
This is interesting. One thing I am fairly sure about, the amount of caffeine makes a difference to my sleep quality. If I have a single cup of coffee in the morning, no more, then my sleep quality seems not to be impacted. If I have several cups of coffee, only in the morning, I feel great for the morning, very stimulated, but my sleep is impacted. I wake up with a buzzing several times a night and have never been a…
Most likely it's the leftover caffeine still in your system that's beyond your personal threshold for quality sleep.
I have the same issue. If I drink two double espressos very early in the morning and then no more after that for the rest of the day, I have no problem falling asleep at night but I keep waking up several times during the night with a buzz, while my gf can drink 3 coffees per day and an espresso after dinner and still sleep.
The only way to get rid of this is reduce my caffeine intake to absolute zero, which is hard when you get the smell and taste of fresh single origin beans. I guess some people are just that much more sensitive to it than others, genetics be dammed. I wish there was a cheap way to measure the caffeine content in the coffees I make so I can precisely determine my personal threshold.