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The vagus nerve orchestrates the mind-body connection

quantamagazine.org

151–160 of 180 posts

Re: The vagus nerve orchestrates the mind-body connection

#151

Earlier quoted context omitted.

I know someone where the main artery into one kidney branches in two. Seems like a possible evolutionary step to bifurcation into more smaller kidneys. ;-)

Anecdata: A family member had one of those third smaller kidneys.

I have that. One normal kidney on one side and two touching but distinct maybe 75% sized kidneys on the other.

Re: The vagus nerve orchestrates the mind-body connection

#152

Earlier quoted context omitted.

Some people wonder why the use of ‘AI’ in pathology is not more effective, and this is part of the reason.

Hmm that is the opposite what I would have expected. Because there is so much variation an AI that has trained on an insane breadth of data should easily be able to outcompete a human on specialized tasks.

Unless that training on exceptions isn't quite enough to convey the principles needed to reason about the domain.

I am sure for some problems it will amaze and for some it will not.

Re: The vagus nerve orchestrates the mind-body connection

#153
post #90

Earlier quoted context omitted.

Gradients, spectrums, distributions; oh my

Gradients, spectrums and distributions describe the quantifiable diversity in humans. People have different heights, weights, eye colors, and other numerically measurable qualities. We’re exposed to this and it’s not surprising. What this thread is talking about is things like extra fingers, missing or extra nerves and muscles, and varying structural differences. I recently started learning a lot about the muscular a…

The genetic code is basically configuring a generic vertebrate body; the same sort of variation we see between vertebrate species we can also see as developmental variation in a species.

Re: The vagus nerve orchestrates the mind-body connection

#154
post #33

I have extracted this (and other) nerves from cadavers, and this circuitous cranial nerve (XII?) is as beautiful and complex as the multibranch plexus -es (e.g. brachial ). So delicate. Human anatomy, at first glance, often seems wrongly-engineered. After you've worked inside dozens of people, you begin to realize that everybody is unique — and nobody is "textbook" anatomy. Who knows what all this goop even does?! If…

This reminds me of a conversation I was having recently about genetically engineering humans. I think people are greatly underestimating the complexity of the human body and it’s nature mechanisms of adaptation. Everyone is a little different - but that’s okay because all the little feedback loops and receptor sites account for changes. Like a drug addict needing more and more to get their fix. There isn’t just one v…

Also one substance can be used in multiple feedback loops in different tissues. Tweaking one loop without touching others will take some finesse.

Re: The vagus nerve orchestrates the mind-body connection

#155
post #71

Earlier quoted context omitted.

"The average man doesn't exist." -United States Air Force

The median man does.

Only when there are an odd number of men. Roughly half the time the median man does not exist either.

Re: The vagus nerve orchestrates the mind-body connection

#156

Earlier quoted context omitted.

My story is very similar. Have had tons of pain and muscle related problems for decades - played a ton of sports like you when i was a kid, and did a lot of physical risk-taking too (skateboarding, bmx-style biking taking them off jump-ramps...) and also had lots of injuries. On top of chronic pain, I had (and still have but is greatly reduced) muscle clenching on the left side of my body - for some reason my body on…

How did you go about finding problematic nerves? I have had issues with nerve pain in my left leg for about 7 years now, did the full gamut of MRI s, bone scans, CT scans, ultrasound and saw about 5 different specialists including a neurologist and nobody has been able to help me. Exercise definitely helps but it doesn’t actually seem to turn the nerves off, just desensitize them. Sitting is very painful as I get pai…

A good peripheral nerve specialist will direct the diagnostic nerve blocks, and he prefers you use his pain management guy who he trusts is doing the nerve blocks properly - so you're getting an actual proper diagnostic response from patient.

Dr. Tollestrup in Las Vegas would be my recommendation - I've done 7 surgeries with him so far. To note, every doctor I've encountered isn't perfect - in this case with Tollestrup, he himself hadn't heard of Eagle's syndrome before, arguably because he's a peripheral nerve expert - and the vagus nerves aren't considered peripheral afaik.

An "LVI Global" trained dentist may be able to help you find a proper bite, to create an orthotic that will allow your low jaw to relax/stop guarding. They try to upsell you to full mouth reconstruction, where they actually make money, although the daytime+nighttime orthotics they make for you aren't cheap either. Part of their protocol is also doing a head/neck CBCT scan - which is what incidentally found the Eagle's syndrome for me.

Re: The vagus nerve orchestrates the mind-body connection

#157
post #77

Physiological responses, the kind relayed from major body organs to the brain via the vagus nerve, are not necessarily your “mind” in the sense that they contribute towards your conscious actions or self-directed goals. But yeah, they send signals which can be interpreted one way vs. another depending on if you’re being mindful. Arousal is especially interesting because you can compress a nerve in the right way and e…

Unfortunately, that link between vagotomy and reduced risk of PD hasn't been supported by subsequent studies. In fact, it wasn't really even supported by the initial study[1]: although the point estimates of the hazard ratios were below 1.0, the confidence intervals did not exclude 1.0 -- or stated differently, at p[1] https://onlinelibrary.wiley.com/doi/10.1002/ana.24448

Re: The vagus nerve orchestrates the mind-body connection

#158

I have extracted this (and other) nerves from cadavers, and this circuitous cranial nerve (XII?) is as beautiful and complex as the multibranch plexus -es (e.g. brachial ). So delicate. Human anatomy, at first glance, often seems wrongly-engineered. After you've worked inside dozens of people, you begin to realize that everybody is unique — and nobody is "textbook" anatomy. Who knows what all this goop even does?! If…

It’s interesting you mention “Nobody is textbook anatomy” I know you’re exaggerating for poetic effect but this might actually be true in some parts of the human anatomy. For example the description of the anatomy of vessels and anastomoses around the knee…I have had a professor tell me that the standard anatomical descriptions for this might all essentially be fiction. Basically the variation in some of these vessel…

there are many interesting anatomic variants one interesting thing is the muscles that move our "grasp" - to cause our fingers to close or open. One muscle, with a "lead" per each finger. anatomic variant is sometimes these include the pinky, sometimes they dont. The pinky has its own set of muscles in either case. If you try moving your fingers you can see there's a bit more traction with the pinky isolation versus other fingers and thats why

Re: The vagus nerve orchestrates the mind-body connection

#159
post #157
post #77

Physiological responses, the kind relayed from major body organs to the brain via the vagus nerve, are not necessarily your “mind” in the sense that they contribute towards your conscious actions or self-directed goals. But yeah, they send signals which can be interpreted one way vs. another depending on if you’re being mindful. Arousal is especially interesting because you can compress a nerve in the right way and e…

Unfortunately, that link between vagotomy and reduced risk of PD hasn't been supported by subsequent studies. In fact, it wasn't really even supported by the initial study[1]: although the point estimates of the hazard ratios were below 1.0, the confidence intervals did not exclude 1.0 -- or stated differently, at p [1] https://onlinelibrary.wiley.com/doi/10.1002/ana.24448

Cool, interesting! Though I wouldn’t be surprised if there are such links, even if this one is not supported by further research. We know that gingivitis can lead to heart disease, so I wouldn’t be surprised to find that gut microbial imbalance could have other implications.

Re: The vagus nerve orchestrates the mind-body connection

#160

I have extracted this (and other) nerves from cadavers, and this circuitous cranial nerve (XII?) is as beautiful and complex as the multibranch plexus -es (e.g. brachial ). So delicate. Human anatomy, at first glance, often seems wrongly-engineered. After you've worked inside dozens of people, you begin to realize that everybody is unique — and nobody is "textbook" anatomy. Who knows what all this goop even does?! If…

So, textbook anatomical pictures are ideal just as ideal gases and point masses are. In the real world, concrete anatomy, concrete gases are different.
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