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Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

nature.com

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Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#211

Post by b800h »

zemvpferreira wrote: post #198
b800h wrote: post #23

Earlier quoted context omitted.

Yep - raising my hand here. I've completely given up caffeine (including decaf, which isn't totally) because after I got a Fitbit, I realised that my morning coffee spiked my heart-rate to 120, and kept it thereabouts, slowly dropping to normal overnight, after which I'd start again. A genome sequence shows I'm a slow metaboliser (I expect more will show up with more research). I feel terrific now.

Slow metaboliser here. Also possibly more prone to caffeine addiction than most, according to said genome sequencing interpretation. I need to cap at 2 espressos per day before noon at most, or I start suffering side effects like poor sleep quality. People really need to reframe their coffee consumption from food to drug and understand their own usage and effects of said drug.

Please try quitting entirely. My cold turkey took a week and a half and involved intense muscle pain (going from drinking a coffee and a tea each day). I believe the caffeine was building up in my system, although I could be wrong.

I strongly recommend Barleycup as an alternative morning cuppa.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#212

Post by snthpy »

dakial1 wrote: post #210
xanderlewis wrote: post #97

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

Well, I don’t actually like the taste of coffee and really drink it because of the caffeine effect. I started drinking coffee at 26 because I got so tired after lunch that I almost passed out on my keyboard at work. This disappeared with the coffee intake. After years (I’m 42) I still don’t like the taste and don’t drink it at night or on weekends/holidays.

OT: I used to get that too until I switched to keto. I used to have tuna mayo sandwiches for lunch. Then I cut out the sandwich (I.e. bread) and just had tuna mayo and no longer got that after lunch low and stayed fuller for longer. It was quite amazing to me that I was fuller from eating less. You don't need to go full keto but try cutting out high GI carbs at lunch and see if it makes a difference.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#213

Post by scotty79 »

xanderlewis wrote: post #97
kkielhofner wrote: post #53

Earlier quoted context omitted.

> highly profitable substance Yes and no. I've been a fan of caffeine pills for years. They are very cheap, readily available (portable), and most importantly to me offer completely consistent dosing. With caffeine pills I'm able to ensure I stay below the FDA recommended maximum daily intake of 400 mg (worst case). Another fun bonus - when a physician asks you what your caffeine intake is and you respond in milligra…

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

If you like the taste, just drink decaf. There's really no reason to ingest caffeine if you just like coffee.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#214

Post by guerrilla »

vouaobrasil wrote: post #190
guerrilla wrote: post #109

Earlier quoted context omitted.

When I understood this is when I formally became an anarchist. Before grasping that, I didn't realize that I really didn't have a choice, no matter what. You serve or you die. Those are the options.

That is absolutely true. And the reason is that if you did have a choice, the system would crumble quite easily since those that find the system intolerable would then have somewhere to go and start something new or just live.

The system didn't crumble in fronteir times, that is to say 99% of history. The global monoply of states is just over a century old. This is new.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#215

Post by pjerem »

scotty79 wrote: post #213
xanderlewis wrote: post #97

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

If you like the taste, just drink decaf. There's really no reason to ingest caffeine if you just like coffee.

Also chicory is pretty good. I thought I hated it because the few times I tasted it it was just cheap industrial chicory.

In fact, once you find a nice quality brand, it’s actually a delicious coffee replacement.

Not really the same taste (but a nice one too) but it sounds like the likeliness of the color and of the bitterness does the job of tricking my brain into considering it’s the same thing, at least "emotionally".

Now I just like them both and I can swap them when I want.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#216

Post by zemvpferreira »

b800h wrote: post #211
zemvpferreira wrote: post #198

Earlier quoted context omitted.

Slow metaboliser here. Also possibly more prone to caffeine addiction than most, according to said genome sequencing interpretation. I need to cap at 2 espressos per day before noon at most, or I start suffering side effects like poor sleep quality. People really need to reframe their coffee consumption from food to drug and understand their own usage and effects of said drug.

Please try quitting entirely. My cold turkey took a week and a half and involved intense muscle pain (going from drinking a coffee and a tea each day). I believe the caffeine was building up in my system, although I could be wrong. I strongly recommend Barleycup as an alternative morning cuppa.

I appreciate the recommendation and will try a period of abstinence this summer, at least. I have quit before, but I find it very challenging to stay away.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#217

Post by kennethh »

guhidalg wrote: post #104
xanderlewis wrote: post #97

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

> Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Not the OP, but to respond to your question I think that Starbucks is actually hitting its customers with a triple-whammy of caffeine, sugar, and fat that most brains can't resist addiction to. Are you sure they actually enjoy Starbucks coffee and not its addictive components?

Was a bit surprised to see that Cold Drinks Now Represent 75 Percent of Starbucks’ Sales. I am guessing most of these cold drinks contains an huge amount of sugar and other sweeteners.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#218

Post by iosguyryan »

redoubt wrote: post #9

Medical engineer here; I would suggest anyone whoms interest was caught by the title to read the Discussion, not Abstract. The authors have made good use of the section to broaden their conclusions, answering some of the questions I've observed in this thread. For anyone starting to second-guess their relationship to sleep and caffeine; do note that this is a small-sample study and that more research is needed before…

To pile on: it’s in Scientific Reports. Not high impact, not highest quality. It’s a 9 day in lab study on mystery taste lab brew coffee (whose brewing was deemed so insignificant to a coffee study that its brew recipe was excluded from the methods section). These sort of setups are useful from a “help me isolate some test cases” point of view, but is obviously as much a perturbation in participants natural lives that it might even outweigh the impact of drinking coffee. Further, it draws conclusions from an acute 5 day caffeine exposure, whereas in real life these participants relationships and adaptations to caffeine are built over a long period of time. The power of the study is small and not scoped for conclusions, but rather pointing to an area of interest for further funding.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#219

Post by xolox »

skhunted wrote: post #102
luqtas wrote: post #101

Earlier quoted context omitted.

i think you are bitting the dust of getting used to the taste of a drug, just like people who drink wine, beer etc. these are literally toxic & you get a natural avoidance response the 1° time you try, with very rare cases of acceptance without repulse

I never understood the acquired taste thing. If I don’t like the taste the first time I try something then there won’t be a second time. Why acquire a taste for something you didn’t originally like?

I got into fermented foods to improve my health, and quite a few of these are acquired tastes for me (and surely also for lots of other people). Milk kefir, water kefir, kombucha, tempeh, koji, natto, these things challenge the taste palate of someone who grew up in the Western world without exposure to fermented foods (e.g. a strong sourness to foods and drinks). I grew to appreciate and in some cases love them because I know what they do for my health. Nowadays I regularly crave fermented foods, but when I started taking them I had to force myself to get accustomed to them.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#220

Post by KronisLV »

bitwize wrote: post #208
xanderlewis wrote: post #97

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

This is Hackernews. Do things because you enjoy them? How can you enjoy life if you don't measure, optimize, and min-max every little thing, and write a little Rust program to track all the data you can post to Show HN? All food is fuel, nothing more, don't treat it as some experience to be savored.

A bit of an exaggerated contrarian comment, sure.

But at the same time sometimes it is a little bit like that - some might like the consistency of caffeine pills, they sure were helpful for me. Others just won't like the taste of coffee that much, I know that I usually go for something with lactose free milk and sugar, otherwise it's a bit unpalatable and too bitter. I don't necessarily have a good taste in coffee anyways, the instant stuff is good enough for me.

Similarly, I'd like to replace maybe 10-20% of my food intake or something with powdered fibre and protein (or something else) to hopefully feel a little less hungry without resorting to high calorie options, because right now I'm getting fat and the hunger I feel is straight up stronger than my willpower at times. Vegetables alone or other healthy snacks do absolutely nothing for that, sucks to have to deal with that. Years ago I had no problem with "starving" myself when needed and maintaining whatever weight felt good, now I no longer have that ability as much.

On the other hand, calling people who enjoy the taste or the experience of getting a fancy drink "caffeine addicts" is unkind and we'd do perfectly fine without belittling others. If they like their fancy drinks, that's cool!

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