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Scientists discover a cause of lupus, possible way to reverse it

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Re: Scientists discover a cause of lupus, possible way to reverse it

#181

90% of House MD plots ruined

Lupus is kind of lousy for the punchy scientific format because it has as a nickname "The Great Imitator." (Note that the porphyrias are known as the "little imitator.") Because of this somewhat Protean nature, lupus can masquerade as quite a lot of things, leading it to be a casual element one would have to bring up and then eliminate in episode after episode. Thus, for screenwriting reasons, it needs a kind of general dismissal which would stick in the mind of viewers ...

Re: Scientists discover a cause of lupus, possible way to reverse it

#182
post #178

Earlier quoted context omitted.

Wiki disagrees about B12 in nori: > A 2014 study reported that dried purple laver ("nori") contains vitamin B12 in sufficient quantities to meet the RDA requirement (Vitamin B12 content: 77.6 μg /100 g dry weight).[19] By contrast, however, a 2017 review concluded that vitamin B12 may be destroyed during metabolism or is converted into inactive B12 analogs during drying and storage.[20] The Academy of Nutrition and D…

Thanks, I was only going off the nutrition label, it shows 60% RDA per sheet. However, the reference link for the academy is broken; I wonder if they’ve changed their stance? Other references indicate raw nori has B12 but the drying process may turn it to an inactive form.

They probably got the numbers for the nutrition label from the earlier study and nobody got around to checking yet.

Re: Scientists discover a cause of lupus, possible way to reverse it

#184
post #151
post #129

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Superintelligence

Probably not a great solution.... When dealing with code we say refactor and simplify. Superintelligence my (rightfully) consider us too complicated and a 'big ball of mud' and replace us with version 2.0.

Alignment? I suppose the type of alignment needed for superintelligence is to plead with it for mercy, on some level.

Re: Scientists discover a cause of lupus, possible way to reverse it

#185
post #122

Earlier quoted context omitted.

> But somewhere along the lines we're going to have think about the R&D of the big picture in non-hand-wavey ways. How?

Likely nanotechnology. Sensors that can reside in your body and give up to the moment details, and chemical factories that we can programmatically make adjustments to the body's existing pathways (reprogramming the immune system, etc.). In other words, better integration and faster feedback loops.

seems like dying is easier

Re: Scientists discover a cause of lupus, possible way to reverse it

#186

I was diagnosed with lupus a few years ago. My mom also had it and passed away after 10 years due to complications. My initial symptoms were severe joint pains, which made daily activities difficult. This happened during the COVID lockdown, which helped me maintain my job. I did a lot of research and tried various treatments. Functional medicines and expensive vitamins didn’t help. I read about long-term fasting and…

If you look at "Goodbye Lupus" by Brooke Goldner it doesn't seem to only be your personal experience.

Re: Scientists discover a cause of lupus, possible way to reverse it

#187
post #166
post #120

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It says "Sorry, the file is absent :("

I am sure it will be there eventually. This is a preprint of the abstract to the paper and I know there are some very smart people on HN but if you can grasp this you are in an entirely much higher orbit https://acrabstracts.org/abstract/cxcl13-t-cell-differentiat... What's interesting is that AHR is also involved in Covid infections so this will highly likely be further researched.

That's my domain so yeah I'm in that orbit.

Re: Scientists discover a cause of lupus, possible way to reverse it

#188

Earlier quoted context omitted.

I have crohn's disease which is also autoimmune and directly related to ingesting certain things. I think a lot of autoimmunity has to do with intestinal bacteria and their relationship to our innate immune system. And to a lesser extent it seems that almost every aspect of life is effected by what we eat, how we feel, how we act, how we grow and die. Maybe in 100 years we'll have fecal tests and bacteria pills to ca…

Quite a few of my friend's that were diagnosed with chron's disease found out that the main culprit seemed to be flour and other foodstuff that had been treated with glyphosate (Roundup). After switching to sourdough bread made from organic flours, and similar choices for masa harina (nixtamilated corn) their issues went away. This was after years of not eating anything with fiber, gluten, or nightshades. Their theor…

I was struggling with digestive issues from about 2019 after a severe work burnout (I think triggered by sleeping with a belly full of casein powder and also don't eat gas station sushi) but finally got to the bottom of them only this year. The solution was holistic, but basically my body's inflammation was so high from stress that my gut couldn't handle a piece of bread or a cup of milk, much less beans or nightshades.

Specifically I have sleeps apnea, my cortisol was 1.5 times the max upper range, my thyroid wasn't getting signals from my brain, I had adrenal fatigue, my B12 levels were low (the liver stores 3 years worth of B12, that's why vegetarians often crash the third year), my D3 was low, my BMI was way too high so aromatase was turning my T to estrogen, basically my levels were all off. My nurse gave me some prescriptions and a supplement cocktail and I found relief within just a few days. My joint pain went away, my patchy hair filled in after a couple of months, no more brain fog, etc. If IBS is a spectrum, then my experience has been that it is curable even if it's been going on for 5 years or more, although Crohn's disease probably has immune system markers that require specific treatments.

Now my digestive issues are in remission and I can eat everything I did before (edit: including gluten), although spicy food maybe overstimulates my peristalsis. So that's just the onset of oldtimers disease I guess.

For some level of immediate relief, try eating mainly big looseleaf salads for a few days, drink kefir, and drink a scoop of organic turmeric powder to calm the inflammation, all daily. I also found 2-4 psyllium husk capsules and a large glass of water daily to be highly beneficial, but watch for flares since there are different types of IBS. And stop all multitasking (edit: choose the path of least anxiety), add slack to your schedule, make 20 minutes per day to meditate, and stop believing that you are stuck and this will last forever. I believe that night terrors and bodily symptoms are our subconscious trying to get our attention so that we do the healing work to address the pain of our isolation and suffering.

Re: Scientists discover a cause of lupus, possible way to reverse it

#189

I was diagnosed with lupus a few years ago. My mom also had it and passed away after 10 years due to complications. My initial symptoms were severe joint pains, which made daily activities difficult. This happened during the COVID lockdown, which helped me maintain my job. I did a lot of research and tried various treatments. Functional medicines and expensive vitamins didn’t help. I read about long-term fasting and…

what is your ethnicity/background? what is the traditional diet of your peoples?

Re: Scientists discover a cause of lupus, possible way to reverse it

#190

Earlier quoted context omitted.

Quite a few of my friend's that were diagnosed with chron's disease found out that the main culprit seemed to be flour and other foodstuff that had been treated with glyphosate (Roundup). After switching to sourdough bread made from organic flours, and similar choices for masa harina (nixtamilated corn) their issues went away. This was after years of not eating anything with fiber, gluten, or nightshades. Their theor…

Hmmm...I recently had my gut biome die off but could not identify any suspects. I bake a lot. The most noteable thing about the whole experience was how amazing my bowel functions are after having to restore the gut biome. They are functioning far better than the many years before I experienced the die off. I used pills from Amazon that had good reviews (Physicians Choice) with a strict raw vegetable diet, and they d…

Just writing to add my similar experience. L. reuteri strain has been particularly helpful to me.
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