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Scientists discover a cause of lupus, possible way to reverse it

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Re: Scientists discover a cause of lupus, possible way to reverse it

#141

Post by idunnoman1222 »

MR_Bulldops wrote: post #47
kylehotchkiss wrote: post #11

Earlier quoted context omitted.

I have a good feeling we're going to make a fairly big impact on cancer in our lifetimes with mRNA and other new discoveries in our lifetime. Autoimmune issues I'm feeling much less confident about. It seems like so many of the therapies are "turn down the immune system". I wish there was wider study into autoimmune derived mental health complications too. Maybe I'm totally wrong on this (and I'm very OK to be proven…

I am here to restore your confidence about autoimmune issues. Recently (and still in many cases) "turn down the immune system" was the treatment for most cancers. Of course, the purpose of anti-cancer drugs isn't to turn down the immune system. It just happens that the side effect of drugs that target cancer cells also target other rapidly-dividing cells like hair, endothelial, and immune cells. In fact, chemotherapy…

Killing quickly dividing cells as a way of modulating immune system is ‘turn down the immune system’

Just as antivirals are actually ‘stop cell division’

Neither of which inspire any confidence

Re: Scientists discover a cause of lupus, possible way to reverse it

#142

Post by nanomonkey »

wholinator2 wrote: post #133
aroopchandra wrote: post #126

I was diagnosed with lupus a few years ago. My mom also had it and passed away after 10 years due to complications. My initial symptoms were severe joint pains, which made daily activities difficult. This happened during the COVID lockdown, which helped me maintain my job. I did a lot of research and tried various treatments. Functional medicines and expensive vitamins didn’t help. I read about long-term fasting and…

I have crohn's disease which is also autoimmune and directly related to ingesting certain things. I think a lot of autoimmunity has to do with intestinal bacteria and their relationship to our innate immune system. And to a lesser extent it seems that almost every aspect of life is effected by what we eat, how we feel, how we act, how we grow and die. Maybe in 100 years we'll have fecal tests and bacteria pills to ca…

Quite a few of my friend's that were diagnosed with chron's disease found out that the main culprit seemed to be flour and other foodstuff that had been treated with glyphosate (Roundup). After switching to sourdough bread made from organic flours, and similar choices for masa harina (nixtamilated corn) their issues went away. This was after years of not eating anything with fiber, gluten, or nightshades.

Their theory was that the herbicides would kill off their gut's natural biome and cause an inability process carbohydrates, fiber and maintain a intestinal mucus layer.

YMMV...but just passing along what has worked for a few of my friends.

Re: Scientists discover a cause of lupus, possible way to reverse it

#143

Post by nanomonkey »

_Adam wrote: post #122
fasa99 wrote: post #121

Earlier quoted context omitted.

Exactly. When our car doesn't run well, a car with perhaps 20,000 parts, we take it to the mechanic who says "yup, issue was your spark plug, fixed". And even then, of course, the car issue may have been multifactorial. Maybe the spark plug failed because the fuel/air mix was off, for example, the spark plug was the symptom. But then we leap from the car with 20,000 parts to a body with a trillion cells each cell wit…

> But somewhere along the lines we're going to have think about the R&D of the big picture in non-hand-wavey ways. How?

Likely nanotechnology. Sensors that can reside in your body and give up to the moment details, and chemical factories that we can programmatically make adjustments to the body's existing pathways (reprogramming the immune system, etc.).

In other words, better integration and faster feedback loops.

Re: Scientists discover a cause of lupus, possible way to reverse it

#144

Post by idunnoman1222 »

colordrops wrote: post #89
notheyarent wrote: post #86

they aren’t cell diseases. It is plant toxins either leaking into the blood stream through intestinal permeability or a problem with peoples livers being fatty and not able to do their job anymore resulting in the bodies inability to remove plant toxins. The toxins cause an immune reaction wherever they build up , rheumatoid arthritis if it’s the joints of the legs and arms etc. Plant toxins include pesticides, fungi…

This idea that plants are toxic and meat is healthy is absurd in the extreme. Historical evidence shows humans at mostly a plant based diet for most of our evolution. And the various large and strong herbivores are completely contradictory to your thesis. It's similar to flat-earth in how easy it is to debunk.

the reason that this bro science works for people is that change can effectuate change EG what you’re doing isn’t working change what you are doing and that can have affect with anything, mind, immune system, you name it, I had RA and it went into remission when I just changed my diet and started eating totally different foods. Now we can say that those foods were the cure all and that everyone eat them, but maybe just change your life a bit You’re doing right now ain’t working

Re: Scientists discover a cause of lupus, possible way to reverse it

#145

Post by MR_Bulldops »

idunnoman1222 wrote: post #141
MR_Bulldops wrote: post #47

Earlier quoted context omitted.

I am here to restore your confidence about autoimmune issues. Recently (and still in many cases) "turn down the immune system" was the treatment for most cancers. Of course, the purpose of anti-cancer drugs isn't to turn down the immune system. It just happens that the side effect of drugs that target cancer cells also target other rapidly-dividing cells like hair, endothelial, and immune cells. In fact, chemotherapy…

Killing quickly dividing cells as a way of modulating immune system is ‘turn down the immune system’ Just as antivirals are actually ‘stop cell division’ Neither of which inspire any confidence

It should inspire confidence that we have moved beyond that for many types of cancer. And if it can be done with cancer treatment, we are closer to doing it with autoimmune and anti-virus treatments.

Re: Scientists discover a cause of lupus, possible way to reverse it

#146

Post by rpaddock »

weberer wrote: post #124
ta988 wrote: post #118

Earlier quoted context omitted.

Do you have research that shows that? What I've read is that there was no real evidence of that.

He's likely referring to solanine poisoning. https://en.wikipedia.org/wiki/Solanine

Yes. Also "inflammation and pain in the joints" can be mistaken for Rheumatoid Arthritis (RA).

We discovered the hard-way that my late wife had issues with this. Multiple doctors diagnosed her with both RA and Lupus. When we got the Nightshades out of her diet and switched to more natural based cleaning products, such as Hemp based soap, shampoo and vinegar for cleaning, her symptoms of RA and Lupus went away. An good allergist finds things like this.

Re: Scientists discover a cause of lupus, possible way to reverse it

#147

Post by maayank »

aroopchandra wrote: post #126

I was diagnosed with lupus a few years ago. My mom also had it and passed away after 10 years due to complications. My initial symptoms were severe joint pains, which made daily activities difficult. This happened during the COVID lockdown, which helped me maintain my job. I did a lot of research and tried various treatments. Functional medicines and expensive vitamins didn’t help. I read about long-term fasting and…

What do you eat for protein in the current diet?

What was your experience with fish?

Re: Scientists discover a cause of lupus, possible way to reverse it

#148

Post by spondylosaurus »

hliyan wrote: post #93
spondylosaurus wrote: post #58

Earlier quoted context omitted.

Hey: do you have any stomach problems? Because that was me (up to and including the arthritis part) and then my "IBS" turned out to be Crohn's disease and once I started treating that 90% of my other shit vanished. Things were so bad back then that I was seriously considering a hip replacement to make the pain stop, but today I just hopped off the exercise bike and feel totally fine.

Oh dear, I hope not. I do tend to have the occasional need to visit the mens room several times a day (but only at a level where it's just the mildest of inconveniences). I'd be really worried if it was IBS. The prospect of that getting "upgraded" to Crohn's is downright terrifying. Maybe I'll ask my GP next time.

It could very well not be that, but I always feel compelled to mention it just in case I can spare someone else the same "three years of confusion to figure out what was wrong" fate that I suffeed :P

And even more broadly speaking, if your immune stuff does progress, the good news is that treating the biggest baddest one (in my case, the Crohn's) usually treats the myriad smaller ones with it. So if you ever end up arthritic enough to get treated for that, the treatment should knock down your psoriasis and other stuff too!

Re: Scientists discover a cause of lupus, possible way to reverse it

#149

Post by aroopchandra »

maayank wrote: post #147
aroopchandra wrote: post #126

I was diagnosed with lupus a few years ago. My mom also had it and passed away after 10 years due to complications. My initial symptoms were severe joint pains, which made daily activities difficult. This happened during the COVID lockdown, which helped me maintain my job. I did a lot of research and tried various treatments. Functional medicines and expensive vitamins didn’t help. I read about long-term fasting and…

What do you eat for protein in the current diet? What was your experience with fish?

I eat a lot of legumes such as lentils, chickpeas, black beans, and peas. I also include tofu made from soy, and nuts like almonds, peanuts, as well as seeds like chia, flaxseeds, and hemp. I use plant-based protein powders too specifically (https://lovecomplement.com/products/complement-organic-vegan...) when I drink green smoothies (3 to 4 meals a week).

Green leafy vegetables also has a lot protein (Kale, Broccoli and Brussels).

I use supplements for B12 which is missing from vegetable foods.

I used to eat fish but when I stopped all animal products I gave up fish as well. I guess if I have fish once in a while it won't hurt me but I have a tendency to overdo it. The main thing for me was to reduce the inflammation when I had the imbalance. This meant stopping everything I thought might cause inflammation until it went away.

My diet was also free of all salts, sugars and oils for few months though I do use them now.

Re: Scientists discover a cause of lupus, possible way to reverse it

#150

Post by pixl97 »

nanomonkey wrote: post #143
_Adam wrote: post #122

Earlier quoted context omitted.

> But somewhere along the lines we're going to have think about the R&D of the big picture in non-hand-wavey ways. How?

Likely nanotechnology. Sensors that can reside in your body and give up to the moment details, and chemical factories that we can programmatically make adjustments to the body's existing pathways (reprogramming the immune system, etc.). In other words, better integration and faster feedback loops.

Just wait till some small percentage people have random immune responses to the nanotechnology just creating another feedback loop in the system.
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