Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

It is time for more holistic practices in mental health

journals.plos.org

Post reply on HN
Print view View original

121–130 of 144 posts

Re: It is time for more holistic practices in mental health

#121

Post by srid »

lynx23 wrote: post #44
can16358p wrote: post #25

I strongly believe we don't have "mental health problems", yet we have a global style of living in "modern society" that is inherently incompatible with the way we evolved: e.g. office-based daily tasks instead of walking and hunting, foods fabricated to stimulate us instead of what we could find in nature, high buildings and cities with sound/light/air pollution instead of a calm, clean nature, always trying to "opt…

[flagged]

It may well take humanity a few more decades before they, en masse, come to terms with the fact that, in the end, it is the human condition itself (not the environment) that needs to change. The environment is fine ... more than fine in fact, would anyone really want to go back to "the old times" if they were to be honest?

Re: It is time for more holistic practices in mental health

#122

Post by NotGMan »

smokel wrote: post #115
NotGMan wrote: post #78

Earlier quoted context omitted.

>> but I sincerely doubt that reducing sugar intake will cure depression And yet you can find people whose depression went away after going low carb, search twitter and youtube.

Yes, but those anecdotes don't prove much, do they? I prefer to take my scientific input from peer reviewed papers, not Twitter or YouTube. One random counterexample for your claim: https://pubmed.ncbi.nlm.nih.gov/36584702/

>> Yes, but those anecdotes don't prove much, do they?

Are you sure? Because it's exactly REAL WORLD N=1 examples that clearly demonstrate that for some people these diets are akin to magic.

How can you dismiss REAL WORLD EXAMPLES?

Yes, they don't work for everyone: but so now people shouldn't try them just because some people don't get better on them?

What kind of logic is that?

Real world examples are all that matter! If it works: great, your problem is gone! If it doesn't: back to the drawing board!

Re: It is time for more holistic practices in mental health

#123

Post by aflorez »

Spod_Gaju wrote: post #112

I am the OP. First, I am glad this post has gotten so much attention and traction. But what if I told you I cured my mental illness at 58 years old, a serious case of Bipolar Disorder Schizoaffective Type that had me on Disability and in and out of psychiatric hospitals since I was in my early 30's? What if I told you it was more than holistic but it was holistic thinking that helped me cure my disorder. Will you all…

Please expand :)

Re: It is time for more holistic practices in mental health

#124

Post by Spod_Gaju »

aflorez wrote: post #123
Spod_Gaju wrote: post #112

I am the OP. First, I am glad this post has gotten so much attention and traction. But what if I told you I cured my mental illness at 58 years old, a serious case of Bipolar Disorder Schizoaffective Type that had me on Disability and in and out of psychiatric hospitals since I was in my early 30's? What if I told you it was more than holistic but it was holistic thinking that helped me cure my disorder. Will you all…

Please expand :)

My disorder was caused by too much ATP in the mitochondria and too little in the cytosol. I have a Partial PNP Deficiency[1].

The higher ATP and GTP in my mitochondria causes higher sensitivity to all the G Protein Coupled Receptors[2], this includes the serotonin and dopamine receptors. So any increases in serotonin was exaggerated leading to psychosis and delusions much like someone would have on psilocybin.

This was cured by a low calorie, high seafood diet, a lot of walking, and limiting exposure to oxidative stressors like air pollution.

Most people however have the opposite problem; too little ATP in the mitochondria and too much in the cytosol. This leads to low energy receptor function. So when that person is exposed to dopamine there is very little reaction so they keep seeking dopamine. Hence we have depression and addiction.

In short, changes in the Purinergic pathway cause mood disorders. And this is not even a radical statement, it is just not well known[3].

So you can see why things like SSRIs will work, but stop working after a while. Since nothing is being done to correct the low mitochondrial ATP.

Comments so far?

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338719/ [2] https://www.guidetopharmacology.org/GRAC/ReceptorFamiliesFor... [3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262688/

Re: It is time for more holistic practices in mental health

#125

Post by [deleted] »

NotGMan wrote: post #122
smokel wrote: post #115

Earlier quoted context omitted.

Yes, but those anecdotes don't prove much, do they? I prefer to take my scientific input from peer reviewed papers, not Twitter or YouTube. One random counterexample for your claim: https://pubmed.ncbi.nlm.nih.gov/36584702/

>> Yes, but those anecdotes don't prove much, do they? Are you sure? Because it's exactly REAL WORLD N=1 examples that clearly demonstrate that for some people these diets are akin to magic. How can you dismiss REAL WORLD EXAMPLES? Yes, they don't work for everyone: but so now people shouldn't try them just because some people don't get better on them? What kind of logic is that? Real world examples are all that matt…

[deleted]

Re: It is time for more holistic practices in mental health

#126

Post by [deleted] »

NotGMan wrote: post #122
smokel wrote: post #115

Earlier quoted context omitted.

Yes, but those anecdotes don't prove much, do they? I prefer to take my scientific input from peer reviewed papers, not Twitter or YouTube. One random counterexample for your claim: https://pubmed.ncbi.nlm.nih.gov/36584702/

>> Yes, but those anecdotes don't prove much, do they? Are you sure? Because it's exactly REAL WORLD N=1 examples that clearly demonstrate that for some people these diets are akin to magic. How can you dismiss REAL WORLD EXAMPLES? Yes, they don't work for everyone: but so now people shouldn't try them just because some people don't get better on them? What kind of logic is that? Real world examples are all that matt…

[deleted]

Re: It is time for more holistic practices in mental health

#127

Post by caskstrength »

ungamedplayer wrote: post #15
xlii wrote: post #12

I agree, but on the other hand I don’t think anyone can do anything. I have a stake in treating ADHD but it’s difficult to even describe what ADHD is to a layperson. Describing the needs is almost impossible as different people have different needs and they often don’t align. What I’m sure of, though, is that “today” is very hostile to mental health. Some people have been focusing on microplastics, impact of drugs, u…

I sometimes am tempted to do the math to determine what kind of life we would have if we did everything we were supposed to do.

A very boring kind.

Re: It is time for more holistic practices in mental health

#128

Post by namaria »

r2_pilot wrote: post #48
ImHereToVote wrote: post #27

Earlier quoted context omitted.

Contemporary systems are an organism to themselves. Guided by natural "artificial" selection. Corporations are like aliens trying to terraform the social landscape so they can survive. I can't image what it will be like when they become even more autonomous.

In fact, the original concept of a corporation was that they were created for a specific purpose and then dissolved once completed. In a way, the fact that modern corporations don't do that is analogous to how cancer is mutated cells that don't stop growing, even to the detriment of the host.

> In fact, the original concept of a corporation was that they were created for a specific purpose and then dissolved once completed

You're wrong there. One of the original corporations grew to become the sovereign power over a whole sub continent and eventually got nationalized into a colonial administration. Another original corporation had a para military mandate and conducted large scale open ended naval warfare in three different continents.

Re: It is time for more holistic practices in mental health

#129

Post by plonk »

Spod_Gaju wrote: post #112

I am the OP. First, I am glad this post has gotten so much attention and traction. But what if I told you I cured my mental illness at 58 years old, a serious case of Bipolar Disorder Schizoaffective Type that had me on Disability and in and out of psychiatric hospitals since I was in my early 30's? What if I told you it was more than holistic but it was holistic thinking that helped me cure my disorder. Will you all…

Doesn't bipolar often get better by itself after 50? That happened to family members and they certainly weren't trying to improve their lifestyle.

Re: It is time for more holistic practices in mental health

#130

Post by smokel »

NotGMan wrote: post #122
smokel wrote: post #115

Earlier quoted context omitted.

Yes, but those anecdotes don't prove much, do they? I prefer to take my scientific input from peer reviewed papers, not Twitter or YouTube. One random counterexample for your claim: https://pubmed.ncbi.nlm.nih.gov/36584702/

>> Yes, but those anecdotes don't prove much, do they? Are you sure? Because it's exactly REAL WORLD N=1 examples that clearly demonstrate that for some people these diets are akin to magic. How can you dismiss REAL WORLD EXAMPLES? Yes, they don't work for everyone: but so now people shouldn't try them just because some people don't get better on them? What kind of logic is that? Real world examples are all that matt…

I find that I have to repeat myself. You seem to be using a kind of reasoning that I don't think is very productive. Are you aware of this?

I could spend some time explaining where I think you go off the rails, but I'm afraid you prefer trolling over learning. Please let me know if I'm mistaken, and I'd be happy to continue the conversation.

Post reply on HN