Boss: You look... particularly excited to be working today Me: I'm just trying this new technique to boost productivity
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Viagra improves brain blood flow and could help to prevent dementia
51–60 of 289 posts
Re: Viagra improves brain blood flow and could help to prevent dementia
#52I’ve read about people using tadalafil as a nootropic in the past. Is there even a difference? It’s so easy to get a prescription these days might be worth a shot.
Tadalafil (Cialis) can be useful for dealing with depressive symptoms. It's commonly used in nootropic circles.
With both viagra and tadalafil, they can negatively effect sleep. So it's hit or miss for a lot of people depending on depressive or anxiety symptoms.
Re: Viagra improves brain blood flow and could help to prevent dementia
#53Earlier quoted context omitted.
You take it for this purpose or why?
It is prescribed for benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating—not just for ED
Just hijacking to add a public health warning about BPH. Like many men as they get older, I was getting up several times a night to pee. Thought I would just put up with it until it got worse.
I went on a yacht for the weekend, drank quite a few beers and crashed to sleep.
I awoke to find out I couldn't pee at all. I can't describe how painful things were by the time I staggered into the emergency department that evening. Definitely the worst experience of my life. A few weeks later a guy was winched off a boat by helicopter with the same condition - one of his mates had been tasked with catheterising him using the rubber fuel hose from the boat's engine, but was unsuccessful.
If you are having trouble urinating, seek medical attention - don't ignore it.
Re: Viagra improves brain blood flow and could help to prevent dementia
#54I’ve read about people using tadalafil as a nootropic in the past. Is there even a difference? It’s so easy to get a prescription these days might be worth a shot.
It's thought to improve neuronal density in the hippocampus and also (higher p) to increase bone density. A lot of bodybuilders and athletes use it for increased blood flow benefits, partly because it seems to have fewer side effects then sidenafil (which can cause mild retinal damage leading to a blue tint in the vision; probably why Pfizer used a blue tint in all their advertising). I have no personal experience with it but the theory seems sound.
Re: Viagra improves brain blood flow and could help to prevent dementia
#55Expect a new tsunami of Viagra spam in 3...2...1...
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Re: Viagra improves brain blood flow and could help to prevent dementia
#56[deleted]
Re: Viagra improves brain blood flow and could help to prevent dementia
#57If this is true they altered zinc metabolism might play a role in dementia since zinc is the cofactor for PDE5, or that people who do not make enough cGMP are prone to dementia (which also means they might be low in GTP and GTP regulates glucose-insulin secretion so...)
So I think they can do better then "here is a pill give me more money".
Re: Viagra improves brain blood flow and could help to prevent dementia
#58First NIH said it does:
https://www.nih.gov/news-events/nih-research-matters/viagra-...
Then it doesn't:
https://www.nih.gov/news-events/news-releases/nih-dream-stud...
Then it does:
https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro...
Who knows what to believe.
Re: Viagra improves brain blood flow and could help to prevent dementia
#59> The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. Each participant received sildenafil, a placebo, and cilostazol (a similar drug) over three-week periods in a randomised order. I feel like dudes will know if they got Viagra or not? It doesn't seem like cilostazol…
Viagra doesn't "make" you hard, you still need sexual stimulus. I've taken it and then the sexual opportunity fell through, so I went back to coding or whatever, and I didn't notice anything different.
Dang, that is a sad tale.
Re: Viagra improves brain blood flow and could help to prevent dementia
#60Viagra increases the effect of nitric oxide, which is bad stuff when it gets into cytochrome complex iv in the mitochondria (IIRC). I would personally suspect based on that, that its effects on brain health would be negative in spite of blood flow.
Nitric oxide bad for you? Pretty sure it is good for you ,otherwise super foods like beets and leafy greens would be bad for you.
Too little NO is bad for you, too much NO is bad for you.