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Ask HN: Have you tried weight loss drugs?

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Re: Ask HN: Have you tried weight loss drugs?

#11
post #6
post #5

What about eating healthier and doing more sport? I heard it works pretty well.

Sports is actually extremely inefficient when you look at the science. However, when you look at anecdotes, it seems to be consistently impactful. I think it's more an issue with how we're calculating calories out.

I think weight loss is more than just calories in/out. Maybe our body reacts to adapt to situations and tried to change the body shape to make it easier for itself. So I think healthy habits are more important and can depend on genetic history too.

Re: Ask HN: Have you tried weight loss drugs?

#12
post #7

Anecdotally, Garcinia seems to be the most useful so far, mostly by lowering appetite. Fat burners mostly rely on 1) increasing metabolism via caffeine 2) making that effect last longer. It seems to make things worse for me by increasing hunger, and sometimes makes me feel tired like when I have a fever and I end up lying around all day. Fevers burn lots of calories too, so I suspect it's artificially creating the sa…

So the weight loss drugs in the show were similar to Garcinia?

Because people seem to be losing appetite and getting addicted xD

Re: Ask HN: Have you tried weight loss drugs?

#14
post #6

Earlier quoted context omitted.

Sports is actually extremely inefficient when you look at the science. However, when you look at anecdotes, it seems to be consistently impactful. I think it's more an issue with how we're calculating calories out.

I think weight loss is more than just calories in/out. Maybe our body reacts to adapt to situations and tried to change the body shape to make it easier for itself. So I think healthy habits are more important and can depend on genetic history too.

I think emotions are a huge part of weight gain and loss and yet most Western medicine seems to almost completely ignore the impact of emotions on the body. Try eating a lot of food when sad—it's hard to take even a bite. Yet it's hard to even realize just how much one is eating when anxious.

I also imagine the emotions impact digestion and storage of fats and a lot more, basically adapting our bodies to our perceived environments, so it kinda baffles me that we don't study the emotional impact more.

Re: Ask HN: Have you tried weight loss drugs?

#15
post #5

What about eating healthier and doing more sport? I heard it works pretty well.

This post is an “Ask HN” about trying weight loss drugs. I don’t think a comment suggesting that people who want to lose weight have low self-discipline and are lazy is very helpful.

Re: Ask HN: Have you tried weight loss drugs?

#16
post #2

> but they didn’t take any clear stand on the matter. So, you refer to South Park for medical advice ?

No, but usually they are trying to prove a point like ‘lazy solutions have great beginnings but don’t end well’. This time it was different and I might be living under a rock but never heard of weight loss drugs.

It was by far one of their most unrelatable escapades. The commentary on the US healthcare system was good, but everything else just felt like Hollywood problems. I think Matt and Trey no longer inhabit the same space as everyone else, and it's showing.

(Other comments: the character interactions felt wrong, Kyle was too willing to help Cartman, and Butters was too willing to help without being cajoled into it first, the shootout scene felt clunky and even gratuitous. It felt very low effort towards the end.)

Re: Ask HN: Have you tried weight loss drugs?

#17
post #6
post #5

What about eating healthier and doing more sport? I heard it works pretty well.

Sports is actually extremely inefficient when you look at the science. However, when you look at anecdotes, it seems to be consistently impactful. I think it's more an issue with how we're calculating calories out.

I am fairly certain I know the answer to this. They normally do these kind of studies on untrained humans, because the point is to prescribe (or not) exercise to people who need to lose weight, which are typically not athletes. The anecdotal success comes from people who play sports (tautologically). The problem is you cannot compare across these two groups because the metabolism and sheer volume of exercise is not comparable. Even a semi serious athlete will put in 5-6 hours of intense training a week. And their bodies are much more efficient, so they can burn way more calories in the same time. This is NOT the same as “Brisk walk and lift some weights 3-4 times a week” they prescribe the study group in a study of untrained athletes. Not even close.

Re: Ask HN: Have you tried weight loss drugs?

#18
1.Ephedrine Caffeine Aspirin (old ECA stack)

2.MuscleTech Vapor X5

3.“Truck stop speed”

Just my experiences, not recommendations or advice, do your own homework.

https://youtu.be/_3-Vlql2ivM James Smith - burning 5000 calories then eating 5000 calories. He also has a video on clenbuterol “fitness industry secret weapon”. Generally helpful exercise/weight loss advice videos.

1: used for boosting exercise and losing weight. Good for boosting energy and the combo reduces caffeine crash. A few sports players have died from using it + bad hearts. It’s still accessible. Seemed like I could eat a massive amount of clean food with a good ratio of protein/fat/carbs, gain strength, and the weight gains were clean while losing waist inches. Tracking body measurements were necessary.

2: exercise and losing weight. Very good stimulant effect and to hit new personal records. Can give headaches so I cut the dose to 1/4 or 1/2. Great for overcoming the not wanting to work out days which leads to more exercise days per week and a more healthy lifestyle.

3: hard to tell what is really in it. Possibly something illegal but if you work 12 hours and need to then drive 12 hours to get home without falling asleep, this was what I would reach for. Found at the checkout counter at popular truck stops.

Re: Ask HN: Have you tried weight loss drugs?

#20
If you can withstand the first few days, a lo carb / zero carb diet will do wonders for your appetite. I don’t know what the long term impacts are of such a diet but I do know from personal experience that it’s drastically improved my ability to withstand cravings.
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