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Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

medicalxpress.com

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Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#81
post #28

Earlier quoted context omitted.

Paul Saladino says a lot of things. Which of his claims are you specifically referencing here?

About fat accumulation and decades of chronic inflammation in the brain being huge factors for Alzheimer's.

I couldn't find any example of him claiming anything related to fat accumulation in the brain. Could you link to an example or copy/paste a quote that you're referring to?

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#82
post #40

Earlier quoted context omitted.

What kind of fat is it? Like is it possible to avoid by avoiding too much fat?

The idea that eating fat leads to higher body fat is the most dangerously-wrong health misconception in history.

>> The idea that eating fat leads to higher body fat is the most dangerously-wrong health misconception in history.

Modern equivalent of medieval leeches and enemas for "fever" (almost anything was called a 'fever' back then) and eating goat testicles for potency. Eating them raw obviously :)

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#83
post #60

Earlier quoted context omitted.

>Joe Rogan promoted You mean he did an episode where he had a conversation with the doctor? Or was the doctor a sponsor of the show where he advertised products? I don't think simply having a conversation about an idea counts as promotion. Advertising is another matter though..

The problem with Joe Rogan is that he's not smart and his audience is not smart. He's a pseudo-intellectual. He gifts crackpots an enormous audience of gullible people. He lends credibility to them with softball interviews devoid of critical analysis. He's spoon-feeding suckers what they want to hear. He couches it all in a thin veneer of balanced reporting and barstool philosophizing, under the guise of fairness, bu…

If he’s not smart why’s he so successful. Why did he have a job hosting fear factor. A job hosting UFC. A job being a stand up comic. He’s also short - which I thought meant the cards are stacked against you? He also has a black belt. They don’t give those out. He currently has the biggest, arguably most successful podcast of all time.

But he’s not smart right? Years and years of winning but he’s not smart.

You are capable of thinking and you are smart but that doesn’t mean you are right. Don’t conflate the two

How can one conclude he isn’t smart? Are you politically charged against him. Has he wronged you or your loved ones? Would you say he was not ‘smart’ if you had write a report for a 3 Letter agency?

You can get to the top once if you’re lucky. But if you keep ending up there…

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#84
post #40

Earlier quoted context omitted.

What kind of fat is it? Like is it possible to avoid by avoiding too much fat?

[flagged]

> The matched subjects who ate meat (including poultry and fish) were more than twice as likely to become demented as their vegetarian counterparts (relative risk 2.18, p = 0.065) and the discrepancy was further widened (relative risk 2.99, p = 0.048) when past meat consumption was taken into account

https://pubmed.ncbi.nlm.nih.gov/8327020/

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#85

Earlier quoted context omitted.

That seems like a needlessly bitter response, why the antipathy?

There is a weird crowd of people on the internet that have convinced themselves that seed oils are the cause of many ailments. It doesn’t have a ton of scientific backing but Joe Rogan promoted some guru doctor a while back that spread the idea to a lot more people.

The saga of John Yudkin and Pure White and Deadly should give you pause.

> https://en.wikipedia.org/wiki/John_Yudkin

> https://en.wikipedia.org/wiki/Pure,_White_and_Deadly

Or you know the article on highly processed foods that made the home page the other day: https://news.ycombinator.com/item?id=39746915 ... Could the seed oils thing be a bit much? Sure. Could canola and its use be part of the problem as a highly processed food. Maybe. Is any one doing the research? None of us know...

Why people have some aversion to seed oils, a highly processed food: "Canola oil is made at a processing facility by slightly heating and then crushing the seed.[34] Almost all commercial canola oil is then extracted using hexane solvent, which is recovered at the end of processing. Finally, the canola oil is refined using water precipitation and organic acid to remove gums and free fatty acids, filtering to remove color, and deodorizing using steam distillation. Sometimes the oil is also bleached for a lighter color." https://en.wikipedia.org/wiki/Rapeseed_oil

I'm not sure that sounds like food...

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#86
post #60

Earlier quoted context omitted.

There is a weird crowd of people on the internet that have convinced themselves that seed oils are the cause of many ailments. It doesn’t have a ton of scientific backing but Joe Rogan promoted some guru doctor a while back that spread the idea to a lot more people.

>Joe Rogan promoted You mean he did an episode where he had a conversation with the doctor? Or was the doctor a sponsor of the show where he advertised products? I don't think simply having a conversation about an idea counts as promotion. Advertising is another matter though..

> I don't think

yes.

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#87
post #60

Earlier quoted context omitted.

>Joe Rogan promoted You mean he did an episode where he had a conversation with the doctor? Or was the doctor a sponsor of the show where he advertised products? I don't think simply having a conversation about an idea counts as promotion. Advertising is another matter though..

The problem with Joe Rogan is that he's not smart and his audience is not smart. He's a pseudo-intellectual. He gifts crackpots an enormous audience of gullible people. He lends credibility to them with softball interviews devoid of critical analysis. He's spoon-feeding suckers what they want to hear. He couches it all in a thin veneer of balanced reporting and barstool philosophizing, under the guise of fairness, bu…

wanting censorship of "unapproved" conversations is objectively worse

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#88

Earlier quoted context omitted.

The problem with Joe Rogan is that he's not smart and his audience is not smart. He's a pseudo-intellectual. He gifts crackpots an enormous audience of gullible people. He lends credibility to them with softball interviews devoid of critical analysis. He's spoon-feeding suckers what they want to hear. He couches it all in a thin veneer of balanced reporting and barstool philosophizing, under the guise of fairness, bu…

If he’s not smart why’s he so successful. Why did he have a job hosting fear factor. A job hosting UFC. A job being a stand up comic. He’s also short - which I thought meant the cards are stacked against you? He also has a black belt. They don’t give those out. He currently has the biggest, arguably most successful podcast of all time. But he’s not smart right? Years and years of winning but he’s not smart. You are c…

> Why did he have a job hosting fear factor. A job hosting UFC

That has no relationship with someone being able to have meaningful discussions on complex topics. Probably even the opposite..

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#89
post #84

Earlier quoted context omitted.

[flagged]

> The matched subjects who ate meat (including poultry and fish) were more than twice as likely to become demented as their vegetarian counterparts (relative risk 2.18, p = 0.065) and the discrepancy was further widened (relative risk 2.99, p = 0.048) when past meat consumption was taken into account https://pubmed.ncbi.nlm.nih.gov/8327020/

That's a small observational study from 1993, with p>.05 outside of the subgroup analysis. Whatever search strategy led you to it is severely flawed.

Re: Root cause of Alzheimer's may be fat buildup in brain cells, research suggests

#90
post #40

Earlier quoted context omitted.

What kind of fat is it? Like is it possible to avoid by avoiding too much fat?

The idea that eating fat leads to higher body fat is the most dangerously-wrong health misconception in history.

Honest question: how? I've never seen anyone who's obese and having a diet that made me go "huh that's odd how can they be obese?"

While the inverse occasionally has been true, generally people who I consider in good shape appear to eat less, and less greasy food.

So while there might be exceptions it seems to be a damn good rule of thumb to me.

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