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High coffee consumption, brain volume and risk of dementia and stroke

tandfonline.com

61–70 of 142 posts

Re: High coffee consumption, brain volume and risk of dementia and stroke

#63
post #2

The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

I'm wagering that these people are just chronically under-slept, using higher amounts of coffee to compensate. The link between chronic poor sleep and dementia is well established.

Caffeine consumption does lead to poor sleep.

Makes sense then that lots of coffee would lead to many nights of low quality sleep thereby increasing the risk of all sorts of bad health outcomes

Re: High coffee consumption, brain volume and risk of dementia and stroke

#64
More and more of these "studies" are popping up, using the UK health database to make hypothesis to what we eat or drink, without really diving into the "why".

I know it's a nice first step for more thorough research proposals, but I think they tend to freak people out.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#66
post #5

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Re: High coffee consumption, brain volume and risk of dementia and stroke

#67

Earlier quoted context omitted.

I'm wagering that these people are just chronically under-slept, using higher amounts of coffee to compensate. The link between chronic poor sleep and dementia is well established.

Caffeine consumption does lead to poor sleep. Makes sense then that lots of coffee would lead to many nights of low quality sleep thereby increasing the risk of all sorts of bad health outcomes

I suspect it's the other way around, or a cyclical effect. Plenty of people simply do not allow themselves a full night of sleep, or feel that they cannot afford a full night of sleep (e.g. working 2 jobs & raising kids), leading to dependence on caffeine for functioning.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#68

Earlier quoted context omitted.

Caffeine consumption does lead to poor sleep. Makes sense then that lots of coffee would lead to many nights of low quality sleep thereby increasing the risk of all sorts of bad health outcomes

I suspect it's the other way around, or a cyclical effect. Plenty of people simply do not allow themselves a full night of sleep, or feel that they cannot afford a full night of sleep (e.g. working 2 jobs & raising kids), leading to dependence on caffeine for functioning.

Yeah it’s probably some kind of feedback loop. Over time the loop leads to more and more caffeine consumption and worse and worse sleep.

I can tell you from personal experience it’s not a good thing to have happen to you. Once I reduced my coffee intake to 0 cups a day my sleep became so happy and blissful.

Alas I’m back to drinking 1-2 cups a day. I hope I never go back to that feedback loop so I make sure to only drink coffee in the morning or early afternoon. Never later on in the day.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#69
Still experimenting with about ~20mg of coffee every other day. Great as part of my pre-workout (as indicated by Huberman's podcast) especially with fats. If I don't add the fats, I definitely feel the edginess and jitteriness...

I don't really need it though, wondering if I'm better off just avoiding it? Heard of many other longevity and neural benefits... something I was expecting in this pretty empty study. Self-experimenting continues...

Re: High coffee consumption, brain volume and risk of dementia and stroke

#70
post #2

The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

Considering the very early effects of dementia start to impact people sometimes decades before it becomes bad enough that they are diagnosed, it's certainly possible that extreme coffee consumption is some kind of self-medication mechanism. Anecdotally, I've seen this a lot with adults with undiagnosed ADHD (including myself until 26). Caffeine can be a (very shitty) alternative to proper stimulant medication that pe…

I drink two cups a day, but I must have them. Self medication. I can't imagine five cups, I wouldn't have time to fit them in. Perhaps I'm a lite-weight.
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