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High coffee consumption, brain volume and risk of dementia and stroke

tandfonline.com

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Re: High coffee consumption, brain volume and risk of dementia and stroke

#2
The article is not claiming causal link, but this is still interesting.

>After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day

Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#6
post #2

The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

Considering the very early effects of dementia start to impact people sometimes decades before it becomes bad enough that they are diagnosed, it's certainly possible that extreme coffee consumption is some kind of self-medication mechanism.

Anecdotally, I've seen this a lot with adults with undiagnosed ADHD (including myself until 26). Caffeine can be a (very shitty) alternative to proper stimulant medication that people don't realise they actually need because of a medical issue. So the end up drinking 4-5 coffees a day instead.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#7
post #3

Caffeine does raise blood pressure. You also drink more of you don't sleep enough. Who knows.

And, it significantly disrupts sleep if you drink it 6 hours before bedtime [1]. Poor sleep is linked to dementia [2] risk.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805807/#:~:tex....

[2] https://www.harvardpilgrim.org/hapiguide/understanding-the-c....

Re: High coffee consumption, brain volume and risk of dementia and stroke

#8

> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.

My mom, both of my sisters and I drink it by the pot. Each of us, every day.

6 cups? That doesn't sound like enough coffee to me.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#9

> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.

That’s like a little more than 2 venti Starbucks.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#10
post #2

The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

Considering the very early effects of dementia start to impact people sometimes decades before it becomes bad enough that they are diagnosed, it's certainly possible that extreme coffee consumption is some kind of self-medication mechanism. Anecdotally, I've seen this a lot with adults with undiagnosed ADHD (including myself until 26). Caffeine can be a (very shitty) alternative to proper stimulant medication that pe…

I've been accused of self medicating with coffee before by a guy who was diagnosed with ADHD in his 40s.

It was funny at first, but then he started pointing things out. Want to ride bikes? We can get coffee on our travels.

I jest, kind of.

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