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High coffee consumption, brain volume and risk of dementia and stroke

tandfonline.com

51–60 of 142 posts

Re: High coffee consumption, brain volume and risk of dementia and stroke

#51

Earlier quoted context omitted.

>My mom, both of my sisters and I drink it by the pot. Each of us, every day. Can I ask how's your sleep?

Sleep was fine. I used to drink it by the pot but I cut back mainly because I'd have to piss too much.

Yes, this is my main motivator when I cut back.

If I have to drive a long drive, as an example, I’ll skip coffee that day. I’d rather save stops.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#52
post #33

I can't access the article. Can somebody tell me what is "a cup" mentioned in the article? How much water and how much caffeine is in one "cup" in this article? All the comments here mentions different number of "cups", but I'm very worried that all are different "cups"

I've looked for this, the BioBank screen is this: https://biobank.ndph.ox.ac.uk/showcase/refer.cgi?id=100319 There is literally no guidance AFAICT. My best estimate is 8 US fl oz as per ChatGPT British still use cups to refer to that sometimes. And caffeine... it varies even from cup to cup, the estimate of 91mg per 8 oz cup is what I use.

Per the article, "Habitual coffee intake was self-reported as cups per day, as part of the touchscreen questionnaire at base line with the question ‘How many cups of coffee do you drink a day?’ "

Sounds like it's based on the colloquial definition, which means... who knows! Self-reported values are very non-specific, since my definition of a 'cup' could mean a 24oz with an added triple shot... or it could mean a weakly brewed cup of instant coffee.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#53
post #47
post #22

Earlier quoted context omitted.

And surely the amount of water is inconsequential, why can't we just use grams of actual coffee? Then we don't have to worry about how many espressos are in a 10oz mug. (Nevermind what that person's considering a standard dose for the espresso!)

Different brew methods extract differing amounts from the coffee, so the amount of water is indeed consequential. Same grams of coffee in to a pour-over vs espresso would result in different amounts of extracted coffee material consumed.

True. I'm inclined to think it would be closer than 'do whatever you want in order to end up with an Xoz drink' though!

Re: High coffee consumption, brain volume and risk of dementia and stroke

#54
post #53
post #47

Earlier quoted context omitted.

Different brew methods extract differing amounts from the coffee, so the amount of water is indeed consequential. Same grams of coffee in to a pour-over vs espresso would result in different amounts of extracted coffee material consumed.

True. I'm inclined to think it would be closer than 'do whatever you want in order to end up with an Xoz drink' though!

Prep method matters so much though. For comparison, a standard double shot of espresso is typically 18g of coffee. This would yield approximately 110mg of caffeine.

By comparison, the same 18g brewed using a pour over method should yield an 8oz cup of coffee with … likely around 170mg of caffeine.

Check out this James Hoffmann video specifically on this topic: https://youtube.com/watch?v=etnMr8oUSDo

Re: High coffee consumption, brain volume and risk of dementia and stroke

#55
post #2

The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

That is interesting. I wonder if it's simply the cadmium and lead found in coffee concentrate in heavy users.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#56
I switched over to fully decaf coffee earlier this year.

One of the coffee roasters nearby me highlighted their decaf single origin and thought to try it on a whim one day. It was so good, I stopped drinking decaf coffee that day and bought three bags of the stuff.

It's been two months since I did this. The biggest benefit I've noticed was feeling how insanely tired I am. Fortunately, I've been working on that problem, but damn, coffee really covers up sleep deprivation well.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#57

Earlier quoted context omitted.

> more than 2 venti Americans will do anything to not use the metric system :)

Venti is the Starbucks name for their largest size cup, which holds 20 ounces. Most people don't really care about the exact, specific volume of fluid, they just go by whatever the cup size happens to be called. At least it is more descriptive than the grande or short cups, or the small / medium / large at other places (even if you have to know that venti is 20 in Italian to make the connection).

I doubt I'm the only obnoxious country dude who rolls into Starbucks and orders a "large". You can ignore their pretentious names, they're very accommodating.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#58
post #2

The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.

Considering the very early effects of dementia start to impact people sometimes decades before it becomes bad enough that they are diagnosed, it's certainly possible that extreme coffee consumption is some kind of self-medication mechanism. Anecdotally, I've seen this a lot with adults with undiagnosed ADHD (including myself until 26). Caffeine can be a (very shitty) alternative to proper stimulant medication that pe…

[deleted]

Re: High coffee consumption, brain volume and risk of dementia and stroke

#60
post #56

I switched over to fully decaf coffee earlier this year. One of the coffee roasters nearby me highlighted their decaf single origin and thought to try it on a whim one day. It was so good, I stopped drinking decaf coffee that day and bought three bags of the stuff. It's been two months since I did this. The biggest benefit I've noticed was feeling how insanely tired I am. Fortunately, I've been working on that proble…

> I switched over to fully decaf coffee earlier this year.

You may want to rethink.

>The association between coffee consumption and dementia was..

> with evidence for higher odds for non-coffee and decaffeinated coffee drinkers and those drinking >6 cups/day, compared to light coffee drinkers.

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